4QWA

TERNARY CRYSTAL STRUCTURES OF A Y-FAMILY DNA POLYMERASE DPO4 FROM SULFOLOBUS SOLFATARICUS in COMPLEX WITH DNA AND (-)3TC-DP

Summary for 4QWA

Related4QW8 4QW9 4QWB 4QWC 4QWD 4QWE
DescriptorDNA polymerase IV, DNA (5'-D(P*GP*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*C)-3'), DNA (5'-D(P*CP*AP*GP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3'), ... (6 entities in total)
Functional Keywordsy-family dna polymerase, transferase-dna complex, transferase/dna
Biological sourceSulfolobus solfataricus
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Cellular locationCytoplasm (Probable) Q97W02
Total number of polymer chains3
Total molecular weight49475.89
Authors
Gaur, V.,Suo, Z. (deposition date: 2014-07-16, release date: 2014-08-27, Last modification date: 2014-09-17)
Primary citation
Gaur, V.,Vyas, R.,Fowler, J.D.,Efthimiopoulos, G.,Feng, J.Y.,Suo, Z.
Structural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymerase.
Nucleic Acids Res., 42:9984-9995, 2014
PubMed: 25104018 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gku709
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2372506.3%4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload