PDB: 1148 resultsInfo pagesStatus searchChemie searchBIRD

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4DQ9	Crystal structure of the minor pseudopilin EPSH from the type II secretion system of Vibrio cholerae Descriptor: CHLORIDE ION, General secretion pathway protein H, SODIUM ION Authors: Raghunathan, K, Vago, F.S, Grindem, D, Ball, T, Wedemeyer, W.J, Arvidson, D.N. Deposit date: 2012-02-15 Release date: 2013-03-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.59 Å) Cite: The 1.59 angstrom resolution structure of the minor pseudopilin EpsH of Vibrio cholerae reveals a long flexible loop. Biochim.Biophys.Acta, 1844, 2013
5WDA	Structure of the PulG pseudopilus Descriptor: CALCIUM ION, General secretion pathway protein G Authors: Lopez-Castilla, A, Thomassin, J.L, Bardiaux, B, Zheng, W, Nivaskumar, M, Yu, X, Nilges, M, Egelman, E.H, Izadi-Pruneyre, N, Francetic, O. Deposit date: 2017-07-04 Release date: 2017-10-25 Last modified: 2020-01-01 Method: ELECTRON MICROSCOPY (5 Å) Cite: Structure of the calcium-dependent type 2 secretion pseudopilus. Nat Microbiol, 2, 2017
2QV8	Structure of the minor pseudopilin EpsH from the Type 2 Secretion System of Vibrio cholerae Descriptor: General secretion pathway protein H Authors: Yanez, M.E, Korotkov, K.V, Abendroth, J, Hol, W.G.J. Deposit date: 2007-08-07 Release date: 2008-02-26 Last modified: 2017-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of the minor pseudopilin EpsH from the Type 2 secretion system of Vibrio cholerae. J.Mol.Biol., 377, 2008
8IVW	Crystal structure of NRP2 in complex with aNRP2-10 Fab fragment Descriptor: Heavy chian of antibody 10V8 Fab fragment, Light chain of antibody 10V8 Fab fragment, Neuropilin-2 Authors: Geng, Y, Zhai, L. Deposit date: 2023-03-29 Release date: 2023-07-12 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.205 Å) Cite: Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer. Sci Transl Med, 15, 2023
6RP8	Crystal Structure of Ipilimumab Fab complexed with CTLA-4 at 2.6A resolution Descriptor: Antibody Ipilimumab heavy chain, Antibody Ipilimumab light chain, Cytotoxic T-lymphocyte protein 4 Authors: Zhang, F, Zhou, A. Deposit date: 2019-05-14 Release date: 2020-07-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structure of Ipilimumab Fab complexed with CTLA-4 at 2.6A resolution To Be Published
5HZ7	High-resolution crystal structure of the minor DNA-binding pilin ComP from Neisseria meningitidis in fusion with MBP Descriptor: 1,2-ETHANEDIOL, ComP, SODIUM ION, ... Authors: Berry, J.-L. Deposit date: 2016-02-02 Release date: 2016-05-18 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.43 Å) Cite: A Comparative Structure/Function Analysis of Two Type IV Pilin DNA Receptors Defines a Novel Mode of DNA Binding. Structure, 24, 2016
5DQ0	Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... Authors: Tsai, Y.I, Rana, R.R, Zachary, I, Djordjevic, S. Deposit date: 2015-09-14 Release date: 2016-09-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site To Be Published
6JC2	Crystal structure of the Fab fragment of ipilimumab Descriptor: SULFATE ION, ipilimumab fab heavy chain, ipilimumab fab light chain Authors: Heo, Y.S. Deposit date: 2019-01-27 Release date: 2019-09-11 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Crystal Structure of the Fab Fragment of an Anti-CTLA-4 Antibody, Ipilimumab, Used for Cancer Immunotherapy Bull.Korean Chem.Soc., 40, 2019
4QDQ	Physical basis for Nrp2 ligand binding Descriptor: GLYCEROL, Neuropilin-2, SULFATE ION Authors: Parker, M.W, Vander Kooi, C.W. Deposit date: 2014-05-14 Release date: 2015-04-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form. Structure, 23, 2015
4RN5	B1 domain of human Neuropilin-1 with acetate ion in a ligand-binding site Descriptor: ACETATE ION, GLYCEROL, Neuropilin-1, ... Authors: Allerston, C.K, Yelland, T.S, Jarvis, A, Jenkins, K, Winfield, N, Cheng, L, Jia, H, Zachary, I, Selwood, D.L, Djordjevic, S. Deposit date: 2014-10-23 Release date: 2015-10-28 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Conserved water molecules in a ligand-binding site of neuropilin-1 To be Published
4QDS	Physical basis for Nrp2 ligand binding Descriptor: ACETATE ION, GLYCEROL, Neuropilin-2 Authors: Parker, M.W, Vander Kooi, C.W. Deposit date: 2014-05-14 Release date: 2015-04-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form. Structure, 23, 2015
5MPZ	Crystal structure of CREBBP bromodomain complexed with CBP007 Descriptor: CREB-binding protein, methyl 2-oxidanylidene-3~{H}-1,3-benzoxazole-6-carboxylate Authors: Zhu, J, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-12-19 Release date: 2017-05-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorg. Med. Chem. Lett., 27, 2017
5MGG	Crystal Structure of BAZ2B bromodomain in complex with 4-chloropyridine derivative 3 Descriptor: 4-chloranyl-~{N}-methyl-pyridine-2-carboxamide, Bromodomain adjacent to zinc finger domain protein 2B Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MGJ	Crystal Structure of BAZ2A bromodomain in complex with 1-methylpyridine derivative 1 Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, ethyl 4-chloranyl-1-methyl-6-oxidanylidene-pyridine-3-carboxylate Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MGL	Crystal Structure of BAZ2A bromodomain in complex with 4-chloropyridine derivative 3 Descriptor: 4-chloranyl-~{N}-methyl-pyridine-2-carboxamide, Bromodomain adjacent to zinc finger domain protein 2A Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.651 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MQG	Crystal structure of CREBBP bromodomain complexed with CBP015 Descriptor: 1-(4-azanyl-3-methoxy-phenyl)ethanone, CREB-binding protein Authors: Zhu, J, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-12-20 Release date: 2017-04-19 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorg. Med. Chem. Lett., 27, 2017
4GZ8	Mouse Semaphorin 3A, domains Sema-PSI-IG Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... Authors: Janssen, B.J.C, Malinauskas, T, Siebold, C, Jones, E.Y. Deposit date: 2012-09-06 Release date: 2012-10-17 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex. Nat.Struct.Mol.Biol., 19, 2012
5MGF	Crystal Structure of BAZ2B bromodomain in complex with 4-propionyl-pyrrole derivative 2 Descriptor: Bromodomain adjacent to zinc finger domain protein 2B, methyl 4-propanoyl-1~{H}-pyrrole-2-carboxylate Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MGE	Crystal structure of BAZ2B bromodomain in complex with 1-methylpyridine derivative 1 Descriptor: Bromodomain adjacent to zinc finger domain protein 2B, ethyl 4-chloranyl-1-methyl-6-oxidanylidene-pyridine-3-carboxylate Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MGM	Crystal Structure of BAZ2A bromodomain in complex with acetophenone derivative 4 Descriptor: 1-(3-pyrimidin-2-yloxyphenyl)ethanone, Bromodomain adjacent to zinc finger domain protein 2A Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5MQE	Crystal structure of CREBBP bromodomain complexed with CBP006 Descriptor: 4-bromanyl-~{N}-methyl-1~{H}-pyrrole-2-carboxamide, CREB-binding protein Authors: Zhu, J, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-12-20 Release date: 2017-04-19 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorg. Med. Chem. Lett., 27, 2017
5MQK	Crystal structure of CREBBP bromodomain complexed with CBP019 Descriptor: 1-(1-methylindol-3-yl)ethanone, CREB-binding protein Authors: Zhu, J, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-12-20 Release date: 2017-04-19 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain. Bioorg. Med. Chem. Lett., 27, 2017
5MGK	Crystal Structure of BAZ2A bromodomain in complex with 4-propionyl-pyrrole derivative 2 Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, methyl 4-propanoyl-1~{H}-pyrrole-2-carboxylate Authors: Lolli, G, Spiliotopoulos, D, Caflisch, A. Deposit date: 2016-11-21 Release date: 2017-04-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.301 Å) Cite: Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
3UFI	Crystal structure of a putative cell adhesion protein (BACOVA_04980) from Bacteroides ovatus ATCC 8483 at 2.18 A resolution Descriptor: CHLORIDE ION, SULFATE ION, hypothetical protein BACOVA_04980 Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2011-11-01 Release date: 2011-12-14 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.18 Å) Cite: A Distinct Type of Pilus from the Human Microbiome. Cell, 165, 2016
3LIU	Crystal structure of Putative cell adhesion protein (YP_001304840.1) from Parabacteroides distasonis ATCC 8503 at 2.05 A resolution Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2010-01-25 Release date: 2010-02-09 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.05 Å) Cite: A Distinct Type of Pilus from the Human Microbiome. Cell, 165, 2016

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