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8UZY
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BU of 8uzy by Molmil
The structure of the native cardiac thin filament troponin core in Ca2+-bound partially activated state from the upper strand
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Galkin, V.E, Risi, C.M.
Deposit date:2023-11-16
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy.
J.Mol.Biol., 436, 2024
8UZX
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BU of 8uzx by Molmil
The structure of the native cardiac thin filament troponin core in Ca2+-bound fully activated state from the upper strand
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Galkin, V.E, Risi, C.M.
Deposit date:2023-11-16
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy.
J.Mol.Biol., 436, 2024
8V04
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BU of 8v04 by Molmil
High resolution TMPRSS2 structure following acylation by nafamostat
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, ...
Authors:Fraser, B.J, Dong, A, Kutera, M, Seitova, A, Li, Y, Hutchinson, A, Edwards, A, Benard, F, Levon, H, Arrowsmith, C.
Deposit date:2023-11-16
Release date:2024-01-31
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:High resolution TMPRSS2 structure following acylation by nafamostat
To Be Published
8UZ1
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BU of 8uz1 by Molmil
Straight actin filament from Arp2/3 branch junction sample (ADP-BeFx)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Chavali, S.S, Chou, S.Z, Sindelar, C.V.
Deposit date:2023-11-14
Release date:2024-01-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
8UZ6
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BU of 8uz6 by Molmil
The structure of the native cardiac thin filament troponin core in Ca2+-free tilted state from the lower strand
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Galkin, V.E, Risi, C.M.
Deposit date:2023-11-14
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy.
J.Mol.Biol., 436, 2024
8UZ5
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BU of 8uz5 by Molmil
The structure of the native cardiac thin filament troponin core in Ca2+-free rotated state from the lower strand
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Galkin, V.E, Risi, C.M.
Deposit date:2023-11-14
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy.
J.Mol.Biol., 436, 2024
8UZ0
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BU of 8uz0 by Molmil
Straight actin filament from Arp2/3 branch junction sample (ADP)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Chavali, S.S, Chou, S.Z, Sindelar, C.V.
Deposit date:2023-11-14
Release date:2024-01-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
8R4U
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BU of 8r4u by Molmil
Structure of salt-inducible kinase 3 with inhibitors
Descriptor: 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-fluoranylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one, SULFATE ION, Serine/threonine-protein kinase SIK3, ...
Authors:Kack, H, Oster, L.
Deposit date:2023-11-14
Release date:2024-03-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.416 Å)
Cite:The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
J.Biol.Chem., 300, 2024
8R4Q
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BU of 8r4q by Molmil
Salt inducible kinase 3 in complex with inhibitor
Descriptor: 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile, SULFATE ION, Serine/threonine-protein kinase SIK3, ...
Authors:Kack, H, Oster, L.
Deposit date:2023-11-14
Release date:2024-03-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.838 Å)
Cite:The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
J.Biol.Chem., 300, 2024
8R4V
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BU of 8r4v by Molmil
Structure of Salt-inducible kinase 3 in complex with inhibitor
Descriptor: 1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]urea, Serine/threonine-protein kinase SIK3
Authors:Kack, H, Oster, L.
Deposit date:2023-11-14
Release date:2024-03-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
J.Biol.Chem., 300, 2024
8R4O
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BU of 8r4o by Molmil
Salt inducible kinase 3 in complex with inhibitor
Descriptor: 2-[bis(fluoranyl)methoxy]-4-[6-(2-cyanopropan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]-~{N}-[(1~{R},2~{S})-2-fluoranylcyclopropyl]-6-methoxy-benzamide, SULFATE ION, Serine/threonine-protein kinase SIK3, ...
Authors:Kack, H, Oster, L.
Deposit date:2023-11-14
Release date:2024-03-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.725 Å)
Cite:The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
J.Biol.Chem., 300, 2024
8UYI
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BU of 8uyi by Molmil
Structure of ADP-bound and phosphorylated Pediculus humanus (Ph) PINK1 dimer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase Pink1, ...
Authors:Gan, Z.Y, Kirk, N.S, Leis, A, Komander, D.
Deposit date:2023-11-13
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Interaction of PINK1 with nucleotides and kinetin.
Sci Adv, 10, 2024
8UYD
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BU of 8uyd by Molmil
The structure of the native cardiac thin filament troponin core in Ca2+-free state from the lower strand
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Galkin, V.E, Risi, C.M.
Deposit date:2023-11-13
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy.
J.Mol.Biol., 436, 2024
8UYF
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BU of 8uyf by Molmil
Structure of nucleotide-free Pediculus humanus (Ph) PINK1 dimer
Descriptor: Serine/threonine-protein kinase Pink1, mitochondrial
Authors:Gan, Z.Y, Kirk, N.S, Leis, A, Komander, D.
Deposit date:2023-11-13
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Interaction of PINK1 with nucleotides and kinetin.
Sci Adv, 10, 2024
8UYH
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BU of 8uyh by Molmil
Structure of AMP-PNP-bound Pediculus humanus (Ph) PINK1 dimer
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Pink1, ...
Authors:Gan, Z.Y, Kirk, N.S, Leis, A, Komander, D.
Deposit date:2023-11-13
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Interaction of PINK1 with nucleotides and kinetin.
Sci Adv, 10, 2024
8UXW
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BU of 8uxw by Molmil
Arp2/3 branch junction complex, ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Chavali, S.S, Chou, S.Z, Sindelar, C.V.
Deposit date:2023-11-11
Release date:2024-01-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
8UXX
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BU of 8uxx by Molmil
Arp2/3 branch junction complex, BeFx state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Chavali, S.S, Chou, S.Z, Sindelar, C.V.
Deposit date:2023-11-11
Release date:2024-01-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
8X2P
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BU of 8x2p by Molmil
The Crystal Structure of LCK from Biortus.
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, TETRAETHYLENE GLYCOL, ...
Authors:Wang, F, Cheng, W, Lv, Z, Meng, Q, Lu, Y.
Deposit date:2023-11-10
Release date:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Crystal Structure of LCK from Biortus.
To Be Published
8X2K
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BU of 8x2k by Molmil
a lipid receptor complex structure
Descriptor: (Z)-N-(2-hydroxyethyl)octadec-9-enamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Geng, C, Yang, D, Jun, X.
Deposit date:2023-11-09
Release date:2024-04-03
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:a lipid receptor complex structure
To Be Published
8X23
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BU of 8x23 by Molmil
The Crystal Structure of MAPK13 from Biortus.
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Mitogen-activated protein kinase 13
Authors:Wang, F, Cheng, W, Yuan, Z, Lin, D, Pan, W.
Deposit date:2023-11-09
Release date:2023-12-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Crystal Structure of MAPK13 from Biortus.
To Be Published
8UX1
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BU of 8ux1 by Molmil
Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle
Descriptor: 153-bp Widom 601 DNA forward strand, 153-bp Widom 601 DNA reverse strand, GTP-binding nuclear protein Ran, ...
Authors:Huang, S.K, Rubinstein, J.L, Kay, L.E.
Deposit date:2023-11-08
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle
To Be Published
8UWW
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BU of 8uww by Molmil
The structure of the native cardiac thin filament troponin core in Ca2+-free state from the upper strand
Descriptor: Actin, alpha cardiac muscle 1, Tropomyosin alpha-1 chain, ...
Authors:Galkin, V.E, Risi, C.M.
Deposit date:2023-11-08
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy.
J.Mol.Biol., 436, 2024
8UWX
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BU of 8uwx by Molmil
The structure of the native cardiac thin filament troponin core in Ca2+-free tilted state from the upper strand
Descriptor: Actin, alpha cardiac muscle 1, Tropomyosin alpha-1 chain, ...
Authors:Galkin, V.E, Risi, C.M.
Deposit date:2023-11-08
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy.
J.Mol.Biol., 436, 2024
8UWY
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BU of 8uwy by Molmil
The structure of the native cardiac thin filament troponin core in Ca2+-free rotated state from the upper strand
Descriptor: Actin, alpha cardiac muscle 1, Tropomyosin alpha-1 chain, ...
Authors:Galkin, V.E, Risi, C.M.
Deposit date:2023-11-08
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy.
J.Mol.Biol., 436, 2024
8X19
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BU of 8x19 by Molmil
Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
Deposit date:2023-11-06
Release date:2024-03-06
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into histone exchange by human SRCAP complex.
Cell Discov, 10, 2024

221716

数据于2024-06-26公开中

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