PDB: 45817 resultsInfo pagesStatus searchChemie searchBIRD

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7CBY	Structure of FOXG1 DNA binding domain bound to DBE2 DNA site Descriptor: DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), ... Authors: Dai, S.Y, Li, J, Chen, Y.H. Deposit date: 2020-06-15 Release date: 2020-10-28 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.646 Å) Cite: Structural Basis for DNA Recognition by FOXG1 and the Characterization of Disease-causing FOXG1 Mutations. J.Mol.Biol., 432, 2020
4O5E	Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable TTP Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... Authors: Koag, M.C, Lee, S. Deposit date: 2013-12-19 Release date: 2014-07-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.532 Å) Cite: Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine. Nucleic Acids Res., 42, 2014
4O5K	Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable CTP Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... Authors: Koag, M.C, Lee, S. Deposit date: 2013-12-19 Release date: 2014-07-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.058 Å) Cite: Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine. Nucleic Acids Res., 42, 2014
4GZ1	Mus Musculus Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex at 1.5 Angstroms resolution Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), FORMIC ACID, ... Authors: Schellenberg, M.J, Williams, R.S. Deposit date: 2012-09-05 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Mechanism of repair of 5'-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2. Nat.Struct.Mol.Biol., 19, 2012
4PHD	Structure of human DNA polymerase beta complexed with A in the template base paired with incoming non-hydrolyzable CTP and MANGANESE Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*AP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... Authors: Koag, M.C, Lee, S. Deposit date: 2014-05-06 Release date: 2014-09-24 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.21 Å) Cite: The spontaneous replication error and the mismatch discrimination mechanisms of human DNA polymerase beta. Nucleic Acids Res., 42, 2015
4PHA	Structure of human DNA polymerase beta complexed with A in the template base paired with incoming non-hydrolyzable CTP Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*AP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... Authors: Koag, M.C, Lee, S. Deposit date: 2014-05-05 Release date: 2014-09-24 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.52 Å) Cite: The spontaneous replication error and the mismatch discrimination mechanisms of human DNA polymerase beta. Nucleic Acids Res., 42, 2015
4N56	Binary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant (Cs3C KlenTaq) with DNA Descriptor: 5'-D(*AP*AP*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3', DNA polymerase I, ... Authors: Wu, E.Y. Deposit date: 2013-10-09 Release date: 2015-01-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A Conservative Isoleucine to Leucine Mutation Causes Major Rearrangements and Cold Sensitivity in KlenTaq1 DNA Polymerase. Biochemistry, 54, 2015
3CMU	Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DT)-3'), MAGNESIUM ION, ... Authors: Pavletich, N.P. Deposit date: 2008-03-24 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (4.2 Å) Cite: Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures. Nature, 453, 2008
7NYX	Cryo-EM structure of the MukBEF-MatP-DNA monomer (closed conformation) Descriptor: 4'-PHOSPHOPANTETHEINE, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... Authors: Buermann, F, Lowe, J. Deposit date: 2021-03-23 Release date: 2021-07-07 Last modified: 2022-03-23 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
7NYW	Cryo-EM structure of the MukBEF-MatP-DNA head module Descriptor: 4'-PHOSPHOPANTETHEINE, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... Authors: Buermann, F, Lowe, J. Deposit date: 2021-03-23 Release date: 2021-07-07 Last modified: 2022-03-23 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
7NZ2	Cryo-EM structure of the MukBEF-MatP-DNA tetrad Descriptor: 4'-PHOSPHOPANTETHEINE, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... Authors: Buermann, F, Lowe, J. Deposit date: 2021-03-23 Release date: 2021-07-07 Last modified: 2022-06-29 Method: ELECTRON MICROSCOPY (11 Å) Cite: Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
7NYZ	Cryo-EM structure of the MukBEF-MatP-DNA monomer (partially open conformation) Descriptor: 4'-PHOSPHOPANTETHEINE, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... Authors: Buermann, F, Lowe, J. Deposit date: 2021-03-23 Release date: 2021-07-07 Last modified: 2022-03-23 Method: ELECTRON MICROSCOPY (6.5 Å) Cite: Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
7NZ0	Cryo-EM structure of the MukBEF-MatP-DNA monomer (open conformation) Descriptor: 4'-PHOSPHOPANTETHEINE, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... Authors: Buermann, F, Lowe, J. Deposit date: 2021-03-23 Release date: 2021-07-07 Last modified: 2022-03-23 Method: ELECTRON MICROSCOPY (6.3 Å) Cite: Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites. Mol.Cell, 81, 2021
7EZJ	Crystal structure of p73 DNA binding domain complex bound with 1 bp and 2 bp spacer DNA response elements. Descriptor: 12-mer DNA, Tumor protein p73, ZINC ION Authors: Koley, T, Roy Chowdhury, S, Kumar, M, Kaur, P, Singh, T.P, Viadiu, H, Ethayathulla, A.S. Deposit date: 2021-06-01 Release date: 2022-04-13 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Deciphering the mechanism of p73 recognition of p53 response elements using the crystal structure of p73-DNA complexes and computational studies. Int.J.Biol.Macromol., 206, 2022
7AW9	CCAAT-binding complex and HapX bound to Aspergillus fumigatus cccA DNA Descriptor: BZIP domain-containing protein, CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, ... Authors: Huber, E.M, Groll, M. Deposit date: 2020-11-06 Release date: 2022-04-13 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX. Structure, 30, 2022
7AW7	CCAAT-binding complex and HapX bound to Aspergillus nidulans cccA DNA Descriptor: BZIP domain-containing protein, CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, ... Authors: Huber, E.M, Groll, M. Deposit date: 2020-11-06 Release date: 2022-04-13 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX. Structure, 30, 2022
6FJ5	New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-AGG-HG) Descriptor: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA, ... Authors: Golovenko, D, Rozenberg, H, Shakked, Z. Deposit date: 2018-01-20 Release date: 2018-06-27 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.051 Å) Cite: New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
2XCP	TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, 7,8- DIHYDRO-8-OXODEOXYGUANINE MODIFIED DNA AND dCTP - MAGNESIUM FORM Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP *TP*DOC)-3', 5'-D(*TP*CP*AP*CP*8OGP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... Authors: Irimia, A, Egli, M. Deposit date: 2010-04-24 Release date: 2010-09-08 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Metal Ion Dependence of the Active Site Conformation of the Trans-Lesion DNA Polymerase Dpo4 from Sulfolobus Solfataricus Acta Crystallogr.,Sect.F, 66, 2010
2XHI	Separation-of-function mutants unravel the dual reaction mode of human 8-oxoguanine DNA glycosylase Descriptor: 5'-D(*GP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... Authors: Dalhus, B, Forsbring, M, Helle, I.H, Backe, P.H, Forstrom, R.J, Alseth, I, Bjoras, M. Deposit date: 2010-06-16 Release date: 2011-01-26 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Separation-of-Function Mutants Unravel the Dual- Reaction Mode of Human 8-Oxoguanine DNA Glycosylase. Structure, 19, 2011
2XCA	TERNARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE, 7,8- DIHYDRO-8-OXODEOXYGUANINE MODIFIED DNA AND dGTP - MAGNESIUM FORM Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*DOC)-3', 5'-D(*TP*CP*AP*CP*8OGP*GP*AP*AP*TP*CP*CP*TP*TP*CP* CP*CP*CP*C)-3', ... Authors: Irimia, A, Egli, M. Deposit date: 2010-04-20 Release date: 2010-09-08 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Metal Ion Dependence of the Active Site Conformation of the Trans-Lesion DNA Polymerase Dpo4 from Sulfolobus Solfataricus Acta Crystallogr.,Sect.F, 66, 2010
2XC9	BINARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE AND 1, N2-ETHENOGUANINE MODIFIED DNA, MAGNESIUM FORM Descriptor: 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*G)-3', 5'-D(*TP*CP*AP*CP*GNEP*GP*AP*AP*TP*CP*CP*TP*TP* CP*CP*CP*CP*C)-3', DNA POLYMERASE IV Authors: Irimia, A, Loukachevitch, L.V, Egli, M. Deposit date: 2010-04-20 Release date: 2010-09-08 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Metal Ion Dependence of the Active Site Conformation of the Trans-Lesion DNA Polymerase Dpo4 from Sulfolobus Solfataricus Acta Crystallogr.,Sect.F, 66, 2010
3RI4	Ets1 cooperative binding to widely separated sites on promoter DNA Descriptor: Isoform Ets-1 p27 of Protein C-ets-1, TCR alpha promoter DNA Authors: Babayeva, N.D, Mino, K, Tahirov, T.H. Deposit date: 2011-04-12 Release date: 2012-04-04 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis of ets1 cooperative binding to widely separated sites on promoter DNA. Plos One, 7, 2012
3CMW	Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DT)-3'), MAGNESIUM ION, ... Authors: Pavletich, N.P. Deposit date: 2008-03-24 Release date: 2008-05-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures. Nature, 453, 2008
5IIM	Crystal structure of the pre-catalytic ternary extension complex of DNA polymerase lambda with an 8-oxo-dG:dA base-pair Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*A)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*(8OG)P*TP*AP*CP*TP*G)-3'), ... Authors: Burak, M.J, Guja, K.E, Garcia-Diaz, M. Deposit date: 2016-03-01 Release date: 2016-09-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.941 Å) Cite: A fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dG. Embo J., 35, 2016
5IIJ	Crystal structure of the pre-catalytic ternary complex of DNA polymerase lambda with a templating 8-oxo-dG and an incoming dCTP Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*CP*GP*GP*CP*(8OG)P*GP*TP*AP*CP*TP*G)-3'), ... Authors: Burak, M.J, Guja, K.E, Garcia-Diaz, M. Deposit date: 2016-03-01 Release date: 2016-08-17 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.724 Å) Cite: A fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dG. Embo J., 35, 2016

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