8QVF
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![BU of 8qvf by Molmil](/molmil-images/mine/8qvf) | Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound. | Descriptor: | 1-(1-adamantyl)-3-(1-methylsulfonylpiperidin-4-yl)urea, Bifunctional epoxide hydrolase 2 | Authors: | Dunge, A, Uwangue, O, Phan, C, Bjelcic, M, Gunnarsson, J, Wehlander, G, Kack, H, Branden, G. | Deposit date: | 2023-10-18 | Release date: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Exploring serial crystallography for drug discovery. Iucrj, 2024
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6DL4
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![BU of 6dl4 by Molmil](/molmil-images/mine/6dl4) | Human Titin ZIg10 | Descriptor: | Titin | Authors: | Wright, N.T. | Deposit date: | 2018-05-31 | Release date: | 2019-08-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural Insights on the Obscurin-Binding Domains in Titin. Protein Pept.Lett., 25, 2018
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7N7C
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![BU of 7n7c by Molmil](/molmil-images/mine/7n7c) | crystal structure of the N-formyltransferase HCAN_0200 from helicobacter canadensis in complex with folinic acid and dTDP-3-aminoquinovose | Descriptor: | 1,2-ETHANEDIOL, Formyl_trans_N domain-containing protein, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ... | Authors: | Heisdorf, C.J, Thoden, J.B, Holden, H.M. | Deposit date: | 2021-06-10 | Release date: | 2021-06-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Investigation of the enzymes required for the biosynthesis of an unusual formylated sugar in the emerging human pathogen Helicobacter canadensis. Protein Sci., 30, 2021
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8QRW
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![BU of 8qrw by Molmil](/molmil-images/mine/8qrw) | ASCT2 protomer in lipid nanodiscs under low Na+ concentration in the intermediate outward-facing state (iOFS-up) | Descriptor: | Neutral amino acid transporter B(0), SODIUM ION | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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8QVH
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![BU of 8qvh by Molmil](/molmil-images/mine/8qvh) | Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound. | Descriptor: | 4-[(trans-4-{[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]dec-1-ylcarbamoyl]amino}cyclohexyl)oxy]benzoic acid, Bifunctional epoxide hydrolase 2 | Authors: | Dunge, A, Uwangue, O, Phan, C, Bjelcic, M, Gunnarsson, J, Wehlander, G, Kack, H, Branden, G. | Deposit date: | 2023-10-18 | Release date: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Exploring serial crystallography for drug discovery. Iucrj, 2024
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8QRR
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![BU of 8qrr by Molmil](/molmil-images/mine/8qrr) | ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.3) | Descriptor: | GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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8QWG
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![BU of 8qwg by Molmil](/molmil-images/mine/8qwg) | Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound. | Descriptor: | Bifunctional epoxide hydrolase 2, TRIETHYLENE GLYCOL | Authors: | Dunge, A, Uwangue, O, Phan, C, Bjelcic, M, Gunnarsson, J, Wehlander, G, Kack, H, Branden, G. | Deposit date: | 2023-10-19 | Release date: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Exploring serial crystallography for drug discovery. Iucrj, 2024
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8ET3
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![BU of 8et3 by Molmil](/molmil-images/mine/8et3) | Cryo-EM structure of a delivery complex containing the SspB adaptor, an ssrA-tagged substrate, and the AAA+ ClpXP protease | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | Authors: | Ghanbarpour, A, Fei, X, Davis, J.H, Sauer, R.T. | Deposit date: | 2022-10-16 | Release date: | 2023-01-25 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | The SspB adaptor drives structural changes in the AAA+ ClpXP protease during ssrA-tagged substrate delivery. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EU4
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![BU of 8eu4 by Molmil](/molmil-images/mine/8eu4) | |
8EZI
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![BU of 8ezi by Molmil](/molmil-images/mine/8ezi) | A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase R98A/R100A variant modeled with separated sulfite and NPN | Descriptor: | 1,2-ETHANEDIOL, 3-methanethioyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium, CALCIUM ION, ... | Authors: | Gatreddi, S, Hausinger, R.P, Hu, J. | Deposit date: | 2022-10-31 | Release date: | 2023-01-25 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Irreversible inactivation of lactate racemase by sodium borohydride reveals reactivity of the nickel-pincer nucleotide cofactor. Acs Catalysis, 13, 2023
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7NNQ
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![BU of 7nnq by Molmil](/molmil-images/mine/7nnq) | Crystal structure of Mycobacterium tuberculosis ArgC in complex with nicotinamide adenine dinucleotide phosphate (NADP+) | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-acetyl-gamma-glutamyl-phosphate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Gupta, P, Mendes, V, Blundell, T.L. | Deposit date: | 2021-02-25 | Release date: | 2021-06-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
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6DOF
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![BU of 6dof by Molmil](/molmil-images/mine/6dof) | |
8QRP
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![BU of 8qrp by Molmil](/molmil-images/mine/8qrp) | ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS.1) | Descriptor: | GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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6DOT
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![BU of 6dot by Molmil](/molmil-images/mine/6dot) | |
8QRU
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![BU of 8qru by Molmil](/molmil-images/mine/8qru) | ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the intermediate outward-facing state (iOFS-down) | Descriptor: | GLUTAMINE, Neutral amino acid transporter B(0) | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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4KJZ
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![BU of 4kjz by Molmil](/molmil-images/mine/4kjz) | |
6DPA
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![BU of 6dpa by Molmil](/molmil-images/mine/6dpa) | |
6DPL
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![BU of 6dpl by Molmil](/molmil-images/mine/6dpl) | |
8QRS
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![BU of 8qrs by Molmil](/molmil-images/mine/8qrs) | ASCT2 protomer in lipid nanodiscs with bound glutamine and Na+ ions in the intermediate outward-facing state (iOFS-up) | Descriptor: | GLUTAMINE, Neutral amino acid transporter B(0) | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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6DQD
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![BU of 6dqd by Molmil](/molmil-images/mine/6dqd) | |
8QVL
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![BU of 8qvl by Molmil](/molmil-images/mine/8qvl) | Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound. | Descriptor: | 2-[(5-BROMO-2-PYRIDYL)-METHYL-AMINO]ETHANOL, Bifunctional epoxide hydrolase 2, DIMETHYL SULFOXIDE, ... | Authors: | Dunge, A, Uwangue, O, Phan, C, Bjelcic, M, Gunnarsson, J, Wehlander, G, Kack, H, Branden, G. | Deposit date: | 2023-10-18 | Release date: | 2024-08-14 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Exploring serial crystallography for drug discovery. Iucrj, 2024
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8EZH
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![BU of 8ezh by Molmil](/molmil-images/mine/8ezh) | A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase R98A/R100A variant modeled with sulfite-NPN adduct | Descriptor: | (4S)-5-methanethioyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-4-sulfo-1,4-dihydropyridine-3-carbothioic S-acid, 1,2-ETHANEDIOL, CALCIUM ION, ... | Authors: | Gatreddi, S, Hausinger, R.P, Hu, J. | Deposit date: | 2022-10-31 | Release date: | 2023-01-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Irreversible inactivation of lactate racemase by sodium borohydride reveals reactivity of the nickel-pincer nucleotide cofactor. Acs Catalysis, 13, 2023
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4KLX
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![BU of 4klx by Molmil](/molmil-images/mine/4klx) | |
6DR0
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![BU of 6dr0 by Molmil](/molmil-images/mine/6dr0) | Class 5 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2018-08-15 | Method: | ELECTRON MICROSCOPY (4.47 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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8QRO
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![BU of 8qro by Molmil](/molmil-images/mine/8qro) | ASCT2 trimer in lipid nanodiscs with bound glutamine and Na+ ions in the outward-facing state (OFS) | Descriptor: | GLUTAMINE, Neutral amino acid transporter B(0), SODIUM ION | Authors: | Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2023-10-09 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
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