7N7C

crystal structure of the N-formyltransferase HCAN_0200 from helicobacter canadensis in complex with folinic acid and dTDP-3-aminoquinovose

Summary for 7N7C

• Entry DOI: 10.2210/pdb7n7c/pdb
• Related: 7n7a 7n7b
• Descriptor: Formyl_trans_N domain-containing protein, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, [(3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate, ... (6 entities in total)
• Functional Keywords: folinic acid, formyltransferase, aminoquinovose, transferase
• Biological source: Helicobacter canadensis MIT 98-5491
• Total number of polymer chains: 2
• Total formula weight: 68437.28

Authors

Heisdorf, C.J.,Thoden, J.B.,Holden, H.M. (deposition date: 2021-06-10, release date: 2021-06-23, Last modification date: 2023-10-18)

• Primary citation: Heisdorf, C.J.,Griffiths, W.A.,Thoden, J.B.,Holden, H.M.; Investigation of the enzymes required for the biosynthesis of an unusual formylated sugar in the emerging human pathogen Helicobacter canadensis.; Protein Sci., 30:2144-2160, 2021; PubMed: 34379357; DOI: 10.1002/pro.4169

Experimental method

X-RAY DIFFRACTION (2 Å)