8EZI

A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase R98A/R100A variant modeled with separated sulfite and NPN

Summary for 8EZI

Entry DOI	10.2210/pdb8ezi/pdb
Descriptor	Lactate racemase, 1,2-ETHANEDIOL, SULFITE ION, ... (9 entities in total)
Functional Keywords	catalytic activity, isomerase activity, racemase and epimerase activity racemase acting on hydroxy acids and derivatives, isomerase, metal ion binding
Biological source	Lactiplantibacillus plantarum WCFS1
Total number of polymer chains	1
Total formula weight	48233.86
Authors	Gatreddi, S.,Hausinger, R.P.,Hu, J. (deposition date: 2022-10-31, release date: 2023-01-25, Last modification date: 2023-11-08)
Primary citation	Gatreddi, S.,Sui, D.,Hausinger, R.P.,Hu, J. Irreversible inactivation of lactate racemase by sodium borohydride reveals reactivity of the nickel-pincer nucleotide cofactor. Acs Catalysis, 13:1441-1448, 2023 Cited by PubMed: 37886035 DOI: 10.1021/acscatal.2c05461 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation