2JRQ
 
 | | NMR solution structure of the anticodon of E. coli TRNA-VAL3 with 1 modification (cmo5U34) | | Descriptor: | 5'-R(*CP*CP*UP*CP*CP*CP*UP*(CM0)P*AP*CP*AP*AP*GP*GP*AP*GP*G)-3' | | Authors: | Vendeix, F.A.P, Dziergowska, A, Gustilo, E.M, Graham, W.D, Sproat, B, Malkiewicz, A, Agris, P.F. | | Deposit date: | 2007-06-28 | | Release date: | 2007-07-24 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Wobble-Position Modifications Pre-structure tRNA's Anticodon for Ribosome-Mediated Codon Binding
To be Published
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5FED
 | | EGFR kinase domain in complex with a covalent aminobenzimidazole inhibitor. | | Descriptor: | Epidermal growth factor receptor, ~{N}-[7-methyl-1-[(3~{R})-1-propanoylazepan-3-yl]benzimidazol-2-yl]-3-(trifluoromethyl)benzamide | | Authors: | DiDonato, M, Spraggon, G. | | Deposit date: | 2015-12-16 | | Release date: | 2016-07-27 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.651 Å) | | Cite: | Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Mutants for the Treatment of EGFR Mutant Non-Small-Cell Lung Cancers.
J.Med.Chem., 59, 2016
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3MPU
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1KEB
 | | Crystal Structure of Double Mutant M37L,P40S E.coli Thioredoxin | | Descriptor: | COPPER (II) ION, Thioredoxin 1 | | Authors: | Rudresh, Jain, R, Dani, V, Mitra, A, Srivastava, S, Sarma, S.P, Varadarajan, R, Ramakumar, S. | | Deposit date: | 2001-11-15 | | Release date: | 2002-11-13 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Consequences of Replacement of an alpha-helical Pro Residue in E.coli Thioredoxin
PROTEIN ENG., 15, 2002
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2JSG
 | | NMR solution structure of the anticodon of E.coli TRNA-VAL3 with 1 modification (M6A37) | | Descriptor: | 5'-R(*CP*CP*UP*CP*CP*CP*UP*UP*AP*CP*(6MZ)P*AP*GP*GP*AP*GP*G)-3' | | Authors: | Vendeix, F.A.P, Dziergowska, A, Gustilo, E.M, Graham, W.D, Sproat, B, Malkiewicz, A, Agris, P.F. | | Deposit date: | 2007-07-04 | | Release date: | 2007-08-07 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Wobble-Position Modifications Pre-structure tRNA's Anticodon for Ribosome-Mediated Codon Binding
To be Published
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2JQM
 | | Yellow Fever Envelope Protein Domain III NMR Structure (S288-K398) | | Descriptor: | Envelope protein E | | Authors: | Volk, D.E, Gandham, S.H, May, F.J, Anderson, A, Barrett, A.D, Gorenstein, D.G. | | Deposit date: | 2007-06-03 | | Release date: | 2008-06-10 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Structure of yellow fever virus envelope protein domain III.
Virology, 394, 2009
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2JRG
 | | NMR solution structure of the anticodon of E. coli TRNA-VAL3 with 2 modifications (cmo5U34 M6A37) | | Descriptor: | 5'-R(*CP*CP*UP*CP*CP*CP*UP*(CM0)P*AP*CP*(6MZ)P*AP*GP*GP*AP*GP*G)-3' | | Authors: | Vendeix, F.A, Dziergowska, A, Gustilo, E.M, Graham, W.D, Sproat, B, Malkiewicz, A, Agris, P.F. | | Deposit date: | 2007-06-26 | | Release date: | 2007-07-24 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Anticodon domain modifications contribute order to tRNA for ribosome-mediated codon binding.
Biochemistry, 47, 2008
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2O3W
 | | Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site in presence of paromomycin | | Descriptor: | PAROMOMYCIN, RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3') | | Authors: | Kondo, J, Hainrichson, M, Nudelman, I, Shallom-Shezifi, D, Baasov, T, Westhof, E. | | Deposit date: | 2006-12-02 | | Release date: | 2007-11-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites.
Chembiochem, 8, 2007
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1PVI
 | | STRUCTURE OF PVUII ENDONUCLEASE WITH COGNATE DNA | | Descriptor: | DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C)-3'), PROTEIN (PVUII (E.C.3.1.21.4)) | | Authors: | Cheng, X, Balendiran, K, Schildkraut, I, Anderson, J.E. | | Deposit date: | 1994-11-16 | | Release date: | 1995-02-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of PvuII endonuclease with cognate DNA.
EMBO J., 13, 1994
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2W2I
 | | Crystal structure of the human 2-oxoglutarate oxygenase LOC390245 | | Descriptor: | 2-OXOGLUTARATE OXYGENASE, GLYCEROL, NICKEL (II) ION, ... | | Authors: | Yue, W.W, Ng, S, Shafqat, N, Ugochukwu, E, McDonough, M, Pike, A.C.W, Filippakopoulos, P, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Schofield, C, Oppermann, U. | | Deposit date: | 2008-10-31 | | Release date: | 2009-01-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human Kdm4 Histone Demethylase Family.
J.Biol.Chem., 286, 2011
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2VYO
 | | Chitin deacetylase family member from Encephalitozoon cuniculi | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | | Authors: | Urch, J.E, Hurtado-Guerrero, R, Texier, C, Van Aalten, D.M.F. | | Deposit date: | 2008-07-25 | | Release date: | 2008-08-12 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural and Functional Characterization of a Putative Polysaccharide Deacetylase of the Human Parasite Encephalitozoon Cuniculi.
Protein Sci., 18, 2009
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4DW3
 | | Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 5'-CMP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYTIDINE-5'-MONOPHOSPHATE, ... | | Authors: | Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. | | Deposit date: | 2012-02-24 | | Release date: | 2012-05-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
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4DWA
 | | Crystal structure of an active-site mutant of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a CpUpC trinucleotide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ... | | Authors: | Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. | | Deposit date: | 2012-02-24 | | Release date: | 2012-05-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
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2ZEO
 | | Crystal structure of the human glutaminyl cyclase mutant D305E at 1.66 angstrom resolution | | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | | Authors: | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | | Deposit date: | 2007-12-13 | | Release date: | 2008-04-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
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1B34
 | | CRYSTAL STRUCTURE OF THE D1D2 SUB-COMPLEX FROM THE HUMAN SNRNP CORE DOMAIN | | Descriptor: | PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1), PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2) | | Authors: | Walke, S, Young, R.J, Kambach, C, Avis, J.M, De La Fortelle, E, Li, J, Nagai, K. | | Deposit date: | 1998-12-17 | | Release date: | 2000-01-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs.
Cell(Cambridge,Mass.), 96, 1999
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1D01
 | | STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A HUMAN CD30 PEPTIDE | | Descriptor: | CD30 PEPTIDE, TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2 | | Authors: | Ye, H, Park, Y.C, Kreishman, M, Kieff, E, Wu, H. | | Deposit date: | 1999-09-07 | | Release date: | 2003-12-02 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structural basis for the recognition of diverse receptor sequences by TRAF2.
Mol.Cell, 4, 1999
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4CG4
 | | Crystal structure of the CHS-B30.2 domains of TRIM20 | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-ETHANETHIOL, PYRIN, ... | | Authors: | Weinert, C, Morger, D, Djekic, A, Mittl, P.R.E, Gruetter, M.G. | | Deposit date: | 2013-11-20 | | Release date: | 2015-04-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of Trim20 C-Terminal Coiled-Coil/B30.2 Fragment: Implications for the Recognition of Higher Order Oligomers
Sci.Rep., 5, 2015
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2ZEF
 | | Crystal structure of the human glutaminyl cyclase mutant E201D at 1.67 angstrom resolution | | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | | Authors: | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | | Deposit date: | 2007-12-12 | | Release date: | 2008-04-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
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1B6E
 | | HUMAN CD94 | | Descriptor: | CD94 | | Authors: | Boyington, J.C, Riaz, A.N, Patamawenu, A, Coligan, J.E, Brooks, A.G, Sun, P.D. | | Deposit date: | 1999-01-14 | | Release date: | 1999-06-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of CD94 reveals a novel C-type lectin fold: implications for the NK cell-associated CD94/NKG2 receptors.
Immunity, 10, 1999
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1D00
 | | STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A 5-RESIDUE CD40 PEPTIDE | | Descriptor: | B-CELL SURFACE ANTIGEN CD40, TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2 | | Authors: | Ye, H, Park, Y.C, Kreishman, M, Kieff, E, Wu, H. | | Deposit date: | 1999-09-07 | | Release date: | 2000-03-29 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structural basis for the recognition of diverse receptor sequences by TRAF2.
Mol.Cell, 4, 1999
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2V1P
 | | Crystal Structure of the apo form of Y74F mutant E. coli tryptophanase | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, TRYPTHOPANASE | | Authors: | Kogan, A, Gdalevsky, G.Y, Cohen-Luria, R, Goldgur, Y, Parola, A.H, Almog, O. | | Deposit date: | 2007-05-28 | | Release date: | 2008-06-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Conformational Changes and Loose Packing Promote E. Coli Tryptophanase Cold Lability.
Bmc Struct.Biol., 9, 2009
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2ZEL
 | | Crystal structure of the human glutaminyl cyclase mutant D248A at 1.97 angstrom resolution | | Descriptor: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | | Authors: | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | | Deposit date: | 2007-12-13 | | Release date: | 2008-04-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis.
Biochem.J., 411, 2008
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2O5W
 | | Structure of the E. coli dihydroneopterin triphosphate pyrophosphohydrolase in complex with Sm+3 and pyrophosphate | | Descriptor: | PYROPHOSPHATE, SAMARIUM (III) ION, SODIUM ION, ... | | Authors: | Gabelli, S.B, Bianchet, M.A, Amzel, L.M. | | Deposit date: | 2006-12-06 | | Release date: | 2007-08-28 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis.
Structure, 15, 2007
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2OOL
 | | Crystal structure of the chromophore-binding domain of an unusual bacteriophytochrome RpBphP3 from R. palustris | | Descriptor: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Sensor protein | | Authors: | Yang, X, Stojkovic, E.A, Kuk, J, Moffat, K. | | Deposit date: | 2007-01-25 | | Release date: | 2007-07-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of the chromophore binding domain of an unusual bacteriophytochrome, RpBphP3, reveals residues that modulate photoconversion.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2KDC
 | | NMR Solution Structure of E. coli diacylglycerol kinase (DAGK) in DPC micelles | | Descriptor: | Diacylglycerol kinase | | Authors: | Van Horn, W.D, Kim, H, Ellis, C.D, Hadziselimovic, A, Sulistijo, E.S, Karra, M.D, Tian, C, Sonnichsen, F.D, Sanders, C.R. | | Deposit date: | 2009-01-06 | | Release date: | 2009-07-07 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution nuclear magnetic resonance structure of membrane-integral diacylglycerol kinase
Science, 324, 2009
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