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7U6A
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BU of 7u6a by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 3-thienylmethyl Benzhydroxamic Acid Inhibitor
Descriptor: 1,2-ETHANEDIOL, N-hydroxy-4-({[(thiophen-3-yl)methyl]amino}methyl)benzamide, PHOSPHATE ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2022-03-03
Release date:2022-04-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Eur.J.Med.Chem., 234, 2022
6MGP
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BU of 6mgp by Molmil
Structure of human 4-1BB / 4-1BBL complex
Descriptor: ACETATE ION, GLYCEROL, Tumor necrosis factor ligand superfamily member 9, ...
Authors:Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y.
Deposit date:2018-09-14
Release date:2018-11-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab
Nat Commun, 9, 2018
7U59
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BU of 7u59 by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Piperidine-4-hydroxamic acid Inhibitor
Descriptor: 1,2-ETHANEDIOL, 1-[2-(benzylamino)ethyl]-N-hydroxypiperidine-4-carboxamide, PHOSPHATE ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2022-03-01
Release date:2023-01-11
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement.
Chembiochem, 23, 2022
6N29
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BU of 6n29 by Molmil
Crystal structure of monomeric von Willebrand Factor D`D3 assembly
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Dong, X, Arndt, J.W, Springer, T.A.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis.
Blood, 133, 2019
6GIW
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BU of 6giw by Molmil
Water-soluble Chlorophyll Protein (WSCP) from Lepidium virginicum (Mutation L91P) with Chlorophyll-a
Descriptor: CHLOROPHYLL A, Water-soluble chlorophyll protein
Authors:Palm, D.M, Agostini, A, Averesch, V, Girr, P, Werwie, M, Takahashi, S, Satoh, H, Jaenicke, E, Paulsen, H.
Deposit date:2018-05-15
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Chlorophyll a/b binding-specificity in water-soluble chlorophyll protein.
Nat Plants, 4, 2018
6GIX
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BU of 6gix by Molmil
Water-soluble Chlorophyll Protein (WSCP) from Lepidium virginicum (Mutation L91P) with Chlorophyll-b
Descriptor: CHLOROPHYLL B, Water-soluble chlorophyll protein
Authors:Palm, D.M, Agostini, A, Averesch, V, Girr, P, Werwie, M, Takahashi, S, Satoh, H, Jaenicke, E, Paulsen, H.
Deposit date:2018-05-15
Release date:2018-10-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Chlorophyll a/b binding-specificity in water-soluble chlorophyll protein.
Nat Plants, 4, 2018
6NOX
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BU of 6nox by Molmil
Solution structure of SFTI-KLK5 inhibitor
Descriptor: SFTI-KLK5 Peptide
Authors:White, A.M.
Deposit date:2019-01-16
Release date:2019-04-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Amino Acid Scanning at P5' within the Bowman-Birk Inhibitory Loop Reveals Specificity Trends for Diverse Serine Proteases.
J. Med. Chem., 62, 2019
7V1N
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BU of 7v1n by Molmil
Structure of the Clade 2 C. difficile TcdB in complex with its receptor TFPI
Descriptor: Isoform Beta of Tissue factor pathway inhibitor, Toxin B
Authors:Luo, J, Yang, Q, Zhang, X, Zhang, Y, Wan, L, Li, Y, Tao, L.
Deposit date:2021-08-05
Release date:2022-02-23
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:TFPI is a colonic crypt receptor for TcdB from hypervirulent clade 2 C. difficile.
Cell, 185, 2022
6NAV
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BU of 6nav by Molmil
Cryo-EM reconstruction of Sulfolobus islandicus LAL14/1 Pilus
Descriptor: M9UD72
Authors:Wang, F, Cvirkaite-Krupovic, V, Prangishvili, D, Krupovic, M, Egelman, E.H.
Deposit date:2018-12-06
Release date:2019-05-08
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:An extensively glycosylated archaeal pilus survives extreme conditions.
Nat Microbiol, 4, 2019
3W0D
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BU of 3w0d by Molmil
Structure of elastase inhibitor AFUEI (cyrstal form I)
Descriptor: Elastase inhibitor AFUEI
Authors:Imada, K, Sakuma, M, Okumura, Y, Ogawa, K, Nikai, T, Homma, M.
Deposit date:2012-10-29
Release date:2013-05-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray Structure Analysis and Characterization of AFUEI, an Elastase Inhibitor from Aspergillus fumigatus
J.Biol.Chem., 288, 2013
3W0E
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BU of 3w0e by Molmil
Structure of elastase inhibitor AFUEI (crystal form II)
Descriptor: Elastase inhibitor AFUEI
Authors:Imada, K, Sakuma, M, Okumura, Y, Ogawa, K, Nikai, T, Homma, M.
Deposit date:2012-10-29
Release date:2013-05-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray Structure Analysis and Characterization of AFUEI, an Elastase Inhibitor from Aspergillus fumigatus
J.Biol.Chem., 288, 2013
7B2T
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BU of 7b2t by Molmil
Crystal structure of Iripin-5 serpin from Ixodes ricinus
Descriptor: CHLORIDE ION, MAGNESIUM ION, Serpin-4 precursor, ...
Authors:Kascakova, B, Kuta Smatanova, I.
Deposit date:2020-11-27
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and biochemical characterization of the novel serpin Iripin-5 from Ixodes ricinus.
Acta Crystallogr D Struct Biol, 77, 2021
7LKP
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BU of 7lkp by Molmil
Structure of ATP-free human ABCA4
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
Authors:Liu, F, Lee, J, Chen, J.
Deposit date:2021-02-02
Release date:2021-03-03
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Molecular structures of the eukaryotic retinal importer ABCA4.
Elife, 10, 2021
7LKZ
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BU of 7lkz by Molmil
Structure of ATP-bound human ABCA4
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Liu, F, Lee, J, Chen, J.
Deposit date:2021-02-03
Release date:2021-03-03
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Molecular structures of the eukaryotic retinal importer ABCA4.
Elife, 10, 2021
7NG4
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BU of 7ng4 by Molmil
P1b-state of wild type human mitochondrial LONP1 protease with bound endogenous substrate protein and in presence of ATP/ADP mix
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
Authors:Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
Deposit date:2021-02-08
Release date:2021-02-24
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NFY
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BU of 7nfy by Molmil
P1a-state of wild type human mitochondrial LONP1 protease with bound substrate protein and ATPgS
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial, ...
Authors:Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
Deposit date:2021-02-08
Release date:2021-02-24
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NG5
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BU of 7ng5 by Molmil
P1c-state of wild type human mitochondrial LONP1 protease with bound substrate protein in presence of ATP/ADP mix
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
Authors:Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
Deposit date:2021-02-08
Release date:2021-02-24
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NGC
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BU of 7ngc by Molmil
P2a-state of wild type human mitochondrial LONP1 protease with bound substrate protein and in presence of ATPgS
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial, ...
Authors:Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
Deposit date:2021-02-09
Release date:2021-04-07
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NGQ
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BU of 7ngq by Molmil
Human mitochondrial Lon protease homolog, D2-state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Mohammed, I, Abrahams, J.P, Schmitz, K.A, Maier, T, Schenck, N.
Deposit date:2021-02-09
Release date:2021-04-28
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NGF
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BU of 7ngf by Molmil
P2c-state of wild type human mitochondrial LONP1 protease with bound endogenous substrate protein and in presence of ATP/ADP mix
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
Authors:Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
Deposit date:2021-02-09
Release date:2021-04-28
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NGP
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BU of 7ngp by Molmil
D1-state of wild type human mitochondrial LONP1 protease
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
Deposit date:2021-02-09
Release date:2021-04-28
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NGL
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BU of 7ngl by Molmil
R-state of wild type human mitochondrial LONP1 protease bound to endogenous ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
Deposit date:2021-02-09
Release date:2021-04-28
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7M5F
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BU of 7m5f by Molmil
Contact-dependent inhibition system from Serratia marcescens BWH57
Descriptor: CdiI, MALONATE ION, Toxin CdiA
Authors:Michalska, K, Nutt, W, Stols, L, Jedrzejczak, R, Hayes, C.S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-03-23
Release date:2021-05-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Contact-dependent inhibition system from Serratia marcescens
To Be Published
7M3Q
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BU of 7m3q by Molmil
Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV)
Descriptor: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, ...
Authors:Chowdhury, A, Singer, A.U, Ogunjimi, A.A, Teyra, J, Zhang, W, Sicheri, F, Sidhu, S.S.
Deposit date:2021-03-18
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV)
To be published
7M1P
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BU of 7m1p by Molmil
Human ABCA4 structure in the unbound state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Retinal-specific phospholipid-transporting ATPase ABCA4, ...
Authors:Scortecci, J.F, Van Petegem, F, Molday, R.S.
Deposit date:2021-03-14
Release date:2021-09-08
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease.
Nat Commun, 12, 2021

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数据于2024-11-06公开中

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