2IWV
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![BU of 2iwv by Molmil](/molmil-images/mine/2iwv) | Structure of the monomeric outer membrane porin OmpG in the open and closed conformation | Descriptor: | CALCIUM ION, LAURYL DIMETHYLAMINE-N-OXIDE, OUTER MEMBRANE PROTEIN G, ... | Authors: | Yildiz, O, Vinothkumar, K.R, Goswami, P, Kuehlbrandt, W. | Deposit date: | 2006-07-04 | Release date: | 2006-08-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the Monomeric Outer-Membrane Porin Ompg in the Open and Closed Conformation. Embo J., 25, 2006
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5L8B
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![BU of 5l8b by Molmil](/molmil-images/mine/5l8b) | Crystal structure of Rhodospirillum rubrum Rru_A0973 mutant E62A | Descriptor: | CALCIUM ION, Uncharacterized protein | Authors: | He, D, Hughes, S, Vanden-Hehir, S, Georgiev, A, Altenbach, K, Tarrant, E, Mackay, C.L, Waldron, K.J, Clarke, D.J, Marles-Wright, J. | Deposit date: | 2016-06-07 | Release date: | 2016-08-31 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments. Elife, 5, 2016
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7SPA
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![BU of 7spa by Molmil](/molmil-images/mine/7spa) | Chlorella virus Hyaluronan Synthase in the GlcNAc-primed, channel-open state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Maloney, F.P, Kuklewicz, J, Zimmer, J. | Deposit date: | 2021-11-02 | Release date: | 2022-04-06 | Last modified: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structure, substrate recognition and initiation of hyaluronan synthase. Nature, 604, 2022
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5KQF
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![BU of 5kqf by Molmil](/molmil-images/mine/5kqf) | (4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-4-methyl-6-pyrimidin-5-yl-5,6-dihydro-1,3-thiazin-2-amine (compound 12) bound to BACE1 | Descriptor: | (4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-4-methyl-6-pyrimidin-5-yl-5,6-dihydro-1,3-thiazin-2-amine, Beta-secretase 1 | Authors: | Lewis, H.A, Wu, Y.J, Rajamani, R, Thompson, L.A. | Deposit date: | 2016-07-06 | Release date: | 2016-09-07 | Last modified: | 2016-10-05 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine beta-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors. J.Med.Chem., 59, 2016
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7E5J
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![BU of 7e5j by Molmil](/molmil-images/mine/7e5j) | Crystal structure of beta-glucosidase from Thermoanaerobacterium saccharolyticum | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, SODIUM ION | Authors: | Nam, K.H. | Deposit date: | 2021-02-18 | Release date: | 2022-02-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Biochemical and Structural Analysis of a Glucose-Tolerant beta-Glucosidase from the Hemicellulose-Degrading Thermoanaerobacterium saccharolyticum. Molecules, 27, 2022
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7TF4
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![BU of 7tf4 by Molmil](/molmil-images/mine/7tf4) | Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) spike protein (focused refinement of RBD) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Zhu, X, Saville, J.W, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Zhou, S, Tuttle, K.S, Subramaniam, S. | Deposit date: | 2022-01-06 | Release date: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants. Nat Commun, 13, 2022
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2M1V
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![BU of 2m1v by Molmil](/molmil-images/mine/2m1v) | |
7Q5D
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![BU of 7q5d by Molmil](/molmil-images/mine/7q5d) | Structure of EPCR in a non-canonical conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Endothelial protein C receptor, ... | Authors: | Lopez-Sagaseta, J, Erausquin, E. | Deposit date: | 2021-11-03 | Release date: | 2022-09-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of EPCR in a non-canonical conformation Biorxiv, 2021
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7SP9
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![BU of 7sp9 by Molmil](/molmil-images/mine/7sp9) | Chlorella virus Hyaluronan Synthase in the GlcNAc-primed channel-closed state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Hyaluronan synthase, ... | Authors: | Maloney, F.P, Kuklewicz, J, Zimmer, J. | Deposit date: | 2021-11-02 | Release date: | 2022-04-06 | Last modified: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure, substrate recognition and initiation of hyaluronan synthase. Nature, 604, 2022
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7AO1
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![BU of 7ao1 by Molmil](/molmil-images/mine/7ao1) | Crystal structure of CotB2 variant W288F in complex with alendronate | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, CHLORIDE ION, ... | Authors: | Dimos, N, Driller, R, Loll, B. | Deposit date: | 2020-10-13 | Release date: | 2020-12-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol. J.Am.Chem.Soc., 142, 2020
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7SP6
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![BU of 7sp6 by Molmil](/molmil-images/mine/7sp6) | Chlorella virus hyaluronan synthase | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL HEMISUCCINATE, Hyaluronan synthase, ... | Authors: | Maloney, F.P, Kuklewicz, J, Zimmer, J. | Deposit date: | 2021-11-02 | Release date: | 2022-04-06 | Last modified: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure, substrate recognition and initiation of hyaluronan synthase. Nature, 604, 2022
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7KHV
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![BU of 7khv by Molmil](/molmil-images/mine/7khv) | CpOGA IN COMPLEX WITH LIGAND 54 | Descriptor: | CALCIUM ION, CHLORIDE ION, N-(5-{[6-(5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-2,6-diazaspiro[3.4]octan-2-yl]methyl}-1,3-thiazol-2-yl)acetamide, ... | Authors: | Shaffer, P.L. | Deposit date: | 2020-10-22 | Release date: | 2020-12-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Diazaspirononane Nonsaccharide Inhibitors of O-GlcNAcase (OGA) for the Treatment of Neurodegenerative Disorders. J.Med.Chem., 63, 2020
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7E52
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![BU of 7e52 by Molmil](/molmil-images/mine/7e52) | |
5LAC
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![BU of 5lac by Molmil](/molmil-images/mine/5lac) | |
7PJM
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![BU of 7pjm by Molmil](/molmil-images/mine/7pjm) | Crystal Structure of Ivosidenib-resistant IDH1 variant R132C S280F in complex with NADPH and Ca2+/2-Oxoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, CALCIUM ION, CHLORIDE ION, ... | Authors: | Reinbold, R, Rabe, P, Abboud, M.I, Schofield, C.J. | Deposit date: | 2021-08-24 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors. Nat Commun, 13, 2022
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2IV1
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![BU of 2iv1 by Molmil](/molmil-images/mine/2iv1) | |
7KJU
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![BU of 7kju by Molmil](/molmil-images/mine/7kju) | Cgi121-tRNA complex | Descriptor: | MAGNESIUM ION, RNA (75-MER) | Authors: | Ceccarelli, D.F, Beenstock, J, Wan, L.C.K, Sicheri, F. | Deposit date: | 2020-10-26 | Release date: | 2020-12-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | A substrate binding model for the KEOPS tRNA modifying complex. Nat Commun, 11, 2020
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7E3N
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![BU of 7e3n by Molmil](/molmil-images/mine/7e3n) | Crystal structure of Isocitrate dehydrogenase D252N mutant from Trypanosoma brucei in complexed with NADP+, alpha-ketoglutarate, and ca2+ | Descriptor: | CALCIUM ION, ISOCITRIC ACID, Isocitrate dehydrogenase [NADP], ... | Authors: | Arai, N, Shiba, T, Inaoka, D.K, Kita, K, Wang, X, Otani, M, Matsushiro, S, Kojima, C. | Deposit date: | 2021-02-09 | Release date: | 2022-02-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Isocitrate dehydrogenase from Trypanosoma brucei. To Be Published
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7SV8
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![BU of 7sv8 by Molmil](/molmil-images/mine/7sv8) | |
7APX
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![BU of 7apx by Molmil](/molmil-images/mine/7apx) | yeast THO-Sub2 complex | Descriptor: | ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2,Tho2, ... | Authors: | Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. | Deposit date: | 2020-10-20 | Release date: | 2020-12-02 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Elife, 9, 2020
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5KR8
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![BU of 5kr8 by Molmil](/molmil-images/mine/5kr8) | (4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine (compound 5) bound to BACE1 | Descriptor: | (4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine, Beta-secretase 1, IODIDE ION | Authors: | Lewis, H.A, Wu, Y.J, Rajamani, R, Thompson, L.A. | Deposit date: | 2016-07-07 | Release date: | 2016-09-07 | Last modified: | 2016-10-05 | Method: | X-RAY DIFFRACTION (2.118 Å) | Cite: | Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine beta-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors. J.Med.Chem., 59, 2016
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2J3R
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![BU of 2j3r by Molmil](/molmil-images/mine/2j3r) | The crystal structure of the bet3-trs31 heterodimer. | Descriptor: | NITRATE ION, PALMITIC ACID, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3, ... | Authors: | Kim, Y.-G, Oh, B.-H. | Deposit date: | 2006-08-23 | Release date: | 2006-11-27 | Last modified: | 2011-10-26 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Architecture of the Multisubunit Trapp I Complex Suggests a Model for Vesicle Tethering. Cell(Cambridge,Mass.), 127, 2006
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7SUW
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![BU of 7suw by Molmil](/molmil-images/mine/7suw) | |
7ARV
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![BU of 7arv by Molmil](/molmil-images/mine/7arv) | TwistTower_native-twist | Descriptor: | SCAFFOLD STRAND, STAPLE STRAND | Authors: | Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H. | Deposit date: | 2020-10-26 | Release date: | 2020-11-18 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (7.4 Å) | Cite: | Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution. Nat Commun, 11, 2020
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5KK3
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![BU of 5kk3 by Molmil](/molmil-images/mine/5kk3) | Atomic Resolution Structure of Monomorphic AB42 Amyloid Fibrils | Descriptor: | Beta-amyloid protein 42 | Authors: | Colvin, M.T, Silvers, R, Zhe Ni, Q, Can, T.V, Sergeyev, I, Rosay, M, Donovan, K.J, Michael, B, Wall, J, Linse, S, Griffin, R.G. | Deposit date: | 2016-06-20 | Release date: | 2016-07-13 | Last modified: | 2024-05-01 | Method: | SOLID-STATE NMR | Cite: | Atomic Resolution Structure of Monomorphic A beta 42 Amyloid Fibrils. J.Am.Chem.Soc., 138, 2016
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