7AO1

Crystal structure of CotB2 variant W288F in complex with alendronate

Summary for 7AO1

• Entry DOI: 10.2210/pdb7ao1/pdb
• Related: 4OMG 4OMH 6GGI 6GGJ 6GGK 6GGL
• Descriptor: Cyclooctat-9-en-7-ol synthase, 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: terpene synthase, cyclooctatin, lyase
• Biological source: Streptomyces melanosporofaciens
• Total number of polymer chains: 2
• Total formula weight: 74524.35

Authors

Dimos, N.,Driller, R.,Loll, B. (deposition date: 2020-10-13, release date: 2020-12-02, Last modification date: 2024-01-31)

• Primary citation: Raz, K.,Driller, R.,Dimos, N.,Ringel, M.,Bruck, T.,Loll, B.,Major, D.T.; The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol.; J.Am.Chem.Soc., 142:21562-21574, 2020; PubMed: 33289561; DOI: 10.1021/jacs.0c11348

Experimental method

X-RAY DIFFRACTION (1.8 Å)