8I09
 
 | | Crystal structure of serine acetyltransferase from Salmonella typhimurium complexed with butyl gallate | | Descriptor: | CYSTEINE, PHOSPHATE ION, Serine acetyltransferase, ... | | Authors: | Toyomoto, T, Ono, K, Shiba, T, Momitani, K, Zhang, T, Tsutsuki, H, Ishikawa, T, Hoso, K, Hamada, K, Rahman, A, Zhong, H, Akaike, T, Yamamoto, K, Matsuoka, M, Hanaoka, K, Niidome, T, Sawa, T. | | Deposit date: | 2023-01-10 | | Release date: | 2023-11-22 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Alkyl gallates inhibit serine O -acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics.
Front Microbiol, 14, 2023
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2VEA
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1F28
 | | CRYSTAL STRUCTURE OF THYMIDYLATE SYNTHASE FROM PNEUMOCYSTIS CARINII BOUND TO DUMP AND BW1843U89 | | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID, THYMIDYLATE SYNTHASE | | Authors: | Anderson, A.C, O'Neil, R.H, Surti, T.S, Stroud, R.M. | | Deposit date: | 2000-05-23 | | Release date: | 2001-06-06 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Approaches to solving the rigid receptor problem by identifying a minimal set of flexible residues during ligand docking.
Chem.Biol., 8, 2001
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8CDD
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8CDE
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5SWC
 | | The structure of the beta-carbonic anhydrase CcaA | | Descriptor: | CHLORIDE ION, Carbonic anhydrase, FORMIC ACID, ... | | Authors: | Kimber, M.S, McGurn, L, White, S.A. | | Deposit date: | 2016-08-08 | | Release date: | 2016-10-26 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The structure, kinetics and interactions of the beta-carboxysomal beta-carbonic anhydrase, CcaA.
Biochem. J., 473, 2016
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7PI7
 | | PfCyRPA bound to monoclonal antibody Cy.002 Fab fragment | | Descriptor: | Cysteine-rich protective antigen, Monoclonal antibody Cy.002 heavy chain, Monoclonal antibody Cy.002 light chain | | Authors: | Ragotte, R.J, Higgins, M.K. | | Deposit date: | 2021-08-19 | | Release date: | 2022-02-09 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.72 Å) | | Cite: | Heterotypic interactions drive antibody synergy against a malaria vaccine candidate.
Nat Commun, 13, 2022
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7PI2
 | | PfCyRPA bound to monoclonal antibody Cy.003 Fab fragment | | Descriptor: | Cysteine-rich protective antigen, Monoclonal antibody Cy.003 heavy chain, Monoclonal antibody Cy.003 light chain | | Authors: | Ragotte, R.J, Higgins, M.K. | | Deposit date: | 2021-08-19 | | Release date: | 2022-02-09 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.14 Å) | | Cite: | Heterotypic interactions drive antibody synergy against a malaria vaccine candidate.
Nat Commun, 13, 2022
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9BAP
 | | CryoEM structure of Apo-DIM2 | | Descriptor: | DNA (cytosine-5-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | Authors: | Song, J, Shao, Z. | | Deposit date: | 2024-04-04 | | Release date: | 2024-07-24 | | Last modified: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Multi-layered heterochromatin interaction as a switch for DIM2-mediated DNA methylation.
Nat Commun, 15, 2024
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9BAZ
 | | CryoEM structure of DIM2-HP1 complex | | Descriptor: | DNA (cytosine-5-)-methyltransferase, Heterochromatin protein one, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Song, J, Shao, Z. | | Deposit date: | 2024-04-05 | | Release date: | 2024-07-24 | | Last modified: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | Multi-layered heterochromatin interaction as a switch for DIM2-mediated DNA methylation.
Nat Commun, 15, 2024
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9BAQ
 | | CryoEM structure of DIM2-HP1-H3K9me3-DNA complex | | Descriptor: | DNA (5'-D(*AP*CP*TP*AP*CP*T)-R(P*(PYO))-D(P*CP*TP*CP*CP*TP*CP*CP*TP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*TP*AP*GP*T)-3'), DNA (cytosine-5-)-methyltransferase, ... | | Authors: | Song, J, Shao, Z. | | Deposit date: | 2024-04-04 | | Release date: | 2024-07-24 | | Last modified: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Multi-layered heterochromatin interaction as a switch for DIM2-mediated DNA methylation.
Nat Commun, 15, 2024
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6LJB
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6LJ9
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6ECU
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5XNK
 | | Crystal structure of Microcystis aeruginosa PCC 7806 aspartate racemase in complex with DL-methyl-aspartate | | Descriptor: | (2S,3S)-3-methyl-aspartic acid, 3-METHYL-BETA-D-ASPARTIC ACID, McyF | | Authors: | Cao, D.D, Zhou, K, Jiang, Y.L, Zhou, C.Z. | | Deposit date: | 2017-05-23 | | Release date: | 2018-05-30 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structure-function Analyses of a Cyanobacterial Aspartate Racemase Reveal Its Catalytic Mechanism and Substrate Specificity
To Be Published
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5XNI
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5D3E
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5D2D
 | | Crystal structure of human 14-3-3 zeta in complex with CFTR R-domain peptide pS753-pS768 | | Descriptor: | 14-3-3 protein zeta/delta, CHLORIDE ION, Cystic fibrosis transmembrane conductance regulator, ... | | Authors: | Stevers, L.M, Leysen, S.F.R, Ottmann, C. | | Deposit date: | 2015-08-05 | | Release date: | 2016-03-16 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5D3F
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5Y2V
 | | Strcutrue of the full-length CcmR complexed with 2-OG from Synechocystis PCC6803 | | Descriptor: | 2-OXOGLUTARIC ACID, PHOSPHATE ION, Rubisco operon transcriptional regulator | | Authors: | Jiang, Y.L, Wang, X.P, Sun, H, Cheng, W, Han, S.J, Li, W.F, Chen, Y, Zhou, C.Z. | | Deposit date: | 2017-07-27 | | Release date: | 2017-12-27 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5DFY
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5DFX
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7R2Y
 | | Carbon regulatory PII-like protein SbtB from Synechocystis sp. 6803 in complex with ATP resulting from short ATP soak, conflicting T-loop and C-loop with partial occupancy | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Membrane-associated protein slr1513, SODIUM ION | | Authors: | Selim, K.A, Albrecht, R, Hartmann, M.D. | | Deposit date: | 2022-02-06 | | Release date: | 2023-02-15 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Carbon signaling protein SbtB possesses atypical redox-regulated apyrase activity to facilitate regulation of bicarbonate transporter SbtA.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7R30
 | | Carbon regulatory PII-like protein SbtB from Synechocystis sp. 6803 in complex with ADP and AMP resulting from ADP soak | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, HEXAETHYLENE GLYCOL, ... | | Authors: | Selim, K.A, Albrecht, R, Hartmann, M.D. | | Deposit date: | 2022-02-06 | | Release date: | 2023-02-15 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Carbon signaling protein SbtB possesses atypical redox-regulated apyrase activity to facilitate regulation of bicarbonate transporter SbtA.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7R2Z
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