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4EHP
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BU of 4ehp by Molmil
Crystal Structure of human vinculin head domain (residues 1-252) in complex with alpha-catenin (residues 277-382)
Descriptor: ACETATE ION, Catenin alpha-1, Vinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2012-04-03
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:alpha-Catenin unfurls upon binding to vinculin
J.Biol.Chem., 287, 2012
9EST
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BU of 9est by Molmil
STRUCTURAL STUDY OF PORCINE PANCREATIC ELASTASE COMPLEXED WITH 7-AMINO-3-(2-BROMOETHOXY)-4-CHLOROISOCOUMARIN AS A NONREACTIVATABLE DOUBLY COVALENT ENZYME-INHIBITOR COMPLEX
Descriptor: (2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATE, CALCIUM ION, PORCINE PANCREATIC ELASTASE, ...
Authors:Radhakrishnan, R, Powers, J.C, Meyer Jr, E.F.
Deposit date:1991-01-14
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural study of porcine pancreatic elastase complexed with 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin as a nonreactivatable doubly covalent enzyme-inhibitor complex.
Biochemistry, 30, 1991
1WPA
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BU of 1wpa by Molmil
1.5 Angstrom crystal structure of human occludin fragment 413-522
Descriptor: Occludin
Authors:Li, Y, Lavie, A, Fanning, A.S, Anderson, J.M.
Deposit date:2004-09-01
Release date:2005-09-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the conserved cytoplasmic C-terminal domain of occludin: identification of the ZO-1 binding surface.
J.Mol.Biol., 352, 2005
3M7I
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BU of 3m7i by Molmil
Crystal structure of transketolase in complex with thiamine diphosphate, ribose-5-phosphate(pyranose form) and magnesium ion
Descriptor: 1,2-ETHANEDIOL, 5-O-phosphono-beta-D-ribofuranose, MAGNESIUM ION, ...
Authors:Nocek, B, Makowska-Grzyska, M, Maltseva, N, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-03-16
Release date:2010-04-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of transketolase in complex with thiamine diphosphate, ribose-5-phosphate(pyranose form) and magnesium ion
TO BE PUBLISHED
4V6V
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BU of 4v6v by Molmil
Tetracycline resistance protein Tet(O) bound to the ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Li, W, Atkinson, G.C, Thakor, N.S, Allas, U, Lu, C, Chan, K.Y, Tenson, T, Schulten, K, Wilson, K.S, Hauryliuk, V, Frank, J.
Deposit date:2013-02-25
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Mechanism of tetracycline resistance by ribosomal protection protein Tet(O).
Nat Commun, 4, 2013
2ZZ9
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BU of 2zz9 by Molmil
Structure of aquaporin-4 S180D mutant at 2.8 A resolution by electron crystallography
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Aquaporin-4
Authors:Tani, K, Mitsuma, T, Hiroaki, Y, Kamegawa, A, Nishikawa, K, Tanimura, Y, Fujiyoshi, Y.
Deposit date:2009-02-06
Release date:2009-06-09
Last modified:2023-11-08
Method:ELECTRON CRYSTALLOGRAPHY (2.8 Å)
Cite:Mechanism of Aquaporin-4's Fast and Highly Selective Water Conduction and Proton Exclusion.
J.Mol.Biol., 389, 2009
7BEX
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BU of 7bex by Molmil
Glyceraldehyde 3-phosphate dehydrogenase from Campylobacter jejeuni - ADP complex
Descriptor: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, BETA-MERCAPTOETHANOL, ...
Authors:Moody, P.C.E, Ayna, A.
Deposit date:2020-12-29
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.054 Å)
Cite:structure of Camplylobacter jejueni GAPDH in complex with ADP
To Be Published
1XAW
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BU of 1xaw by Molmil
crystal structure of the cytoplasmic distal C-terminal domain of occludin
Descriptor: Occludin
Authors:Li, Y, Fanning, A.S, Anderson, J.M, Lavie, A.
Deposit date:2004-08-26
Release date:2005-09-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of the Conserved Cytoplasmic C-terminal Domain of Occludin: Identification of the ZO-1 Binding Surface.
J.Mol.Biol., 352, 2005
7CQ2
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BU of 7cq2 by Molmil
Crystal structure of Slx1-Slx4
Descriptor: GLYCEROL, SLX4 isoform 1, Structure-specific endonuclease subunit SLX1, ...
Authors:Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M.
Deposit date:2020-08-08
Release date:2021-06-16
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex.
Nucleic Acids Res., 49, 2021
7CQ3
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BU of 7cq3 by Molmil
Crystal structure of Slx1-Slx4
Descriptor: SLX4 isoform 1, SULFATE ION, Structure-specific endonuclease subunit SLX1, ...
Authors:Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M.
Deposit date:2020-08-08
Release date:2021-06-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex.
Nucleic Acids Res., 49, 2021
7CQ4
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BU of 7cq4 by Molmil
Crystal structure of Slx1-Slx4 in complex with 5'flap DNA
Descriptor: DNA (27-MER), DNA (5'-D(*AP*GP*GP*AP*CP*AP*TP*CP*TP*TP*TP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*TP*AP*CP*AP*AP*CP*AP*GP*AP*T)-3'), ...
Authors:Xu, X, Wang, M, Sun, J, Li, G, Yang, N, Xu, R.M.
Deposit date:2020-08-08
Release date:2021-06-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.294 Å)
Cite:Structure specific DNA recognition by the SLX1-SLX4 endonuclease complex.
Nucleic Acids Res., 49, 2021
3AXA
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BU of 3axa by Molmil
Crystal structure of afadin PDZ domain in complex with the C-terminal peptide from nectin-3
Descriptor: Afadin, Nectin-3
Authors:Fujiwara, Y, Goda, N, Narita, H, Satomura, K, Nakagawa, A, Sakisaka, T, Suzuki, M, Hiroaki, H.
Deposit date:2011-03-31
Release date:2012-04-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Crystal structure of afadin PDZ domain-nectin-3 complex shows the structural plasticity of the ligand-binding site.
Protein Sci., 24, 2015
7D6F
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BU of 7d6f by Molmil
The crystal structure of ARMS-PBM/MAGI2-PDZ4
Descriptor: GLYCEROL, Kinase D-interacting substrate of 220 kDa, Membrane-associated guanylate kinase, ...
Authors:Ye, J, Zhang, Y, Zhong, Z, Wang, C.
Deposit date:2020-09-30
Release date:2020-11-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Crystal structure of the PDZ4 domain of MAGI2 in complex with PBM of ARMS reveals a canonical PDZ recognition mode.
Neurochem.Int., 149, 2021
2RK4
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BU of 2rk4 by Molmil
Structure of M26I DJ-1
Descriptor: Protein DJ-1
Authors:Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A.
Deposit date:2007-10-16
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1.
Biochemistry, 47, 2008
1ELF
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BU of 1elf by Molmil
NATURE OF THE INACTIVATION OF ELASTASE BY N-PEPTIDYL-O-AROYL HYDROXYLAMINE AS A FUNCTION OF PH
Descriptor: (TERT-BUTYLOXYCARBONYL)-ALANYL-AMINO ETHYL-FORMAMIDE, CALCIUM ION, PORCINE PANCREATIC ELASTASE, ...
Authors:Ding, X, Rasmussen, B, Demuth, H.-U, Ringe, D, Steinmetz, A.C.U.
Deposit date:1995-03-13
Release date:1995-07-10
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Nature of the inactivation of elastase by N-peptidyl-O-aroyl hydroxylamine as a function of pH.
Biochemistry, 34, 1995
3DFZ
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BU of 3dfz by Molmil
SirC, precorrin-2 dehydrogenase
Descriptor: GLYCEROL, Precorrin-2 dehydrogenase, SULFATE ION
Authors:Schubert, H.L, Hill, C.P, Warren, M.J.
Deposit date:2008-06-12
Release date:2008-10-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and function of SirC from Bacillus megaterium: a metal-binding precorrin-2 dehydrogenase
Biochem.J., 415, 2008
2RK3
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BU of 2rk3 by Molmil
Structure of A104T DJ-1
Descriptor: Protein DJ-1
Authors:Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A.
Deposit date:2007-10-16
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1.
Biochemistry, 47, 2008
2RK6
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BU of 2rk6 by Molmil
Structure of E163K DJ-1
Descriptor: Protein DJ-1
Authors:Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A.
Deposit date:2007-10-16
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1.
Biochemistry, 47, 2008
7D9N
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BU of 7d9n by Molmil
Crystal structure of a non-canonic progeria mutation S143F at lamin A/C and its structural implication to the premature aging
Descriptor: Lamin-A/C
Authors:Ahn, J, Jung, S, Ha, N.
Deposit date:2020-10-14
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal structure of progeria mutant S143F lamin A/C reveals increased hydrophobicity driving nuclear deformation.
Commun Biol, 5, 2022
7RN0
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BU of 7rn0 by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor Jun9-57-3R
Descriptor: (2R)-2-{acetyl[4-(1H-pyrrol-1-yl)phenyl]amino}-N-[(1S)-1-phenylethyl]-2-(pyridin-3-yl)acetamide, 3C-like proteinase, GLYCEROL
Authors:Sacco, M, Chen, Y.
Deposit date:2021-07-28
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity.
J.Am.Chem.Soc., 143, 2021
7RN1
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BU of 7rn1 by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor Jun9-62-2R
Descriptor: 3C-like proteinase, GLYCEROL, N-([1,1'-biphenyl]-4-yl)-2-chloro-N-[(1R)-2-oxo-2-{[(1S)-1-phenylethyl]amino}-1-(pyridin-3-yl)ethyl]acetamide, ...
Authors:Sacco, M, Chen, Y.
Deposit date:2021-07-28
Release date:2021-09-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity.
J.Am.Chem.Soc., 143, 2021
1GRO
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BU of 1gro by Molmil
REGULATORY AND CATALYTIC MECHANISMS IN ESCHERICHIA COLI ISOCITRATE DEHYDROGENASE: MULTIPLE ROLES FOR N115
Descriptor: ISOCITRATE DEHYDROGENASE, ISOCITRIC ACID, MAGNESIUM ION
Authors:Grobler, J.A, Hurley, J.H.
Deposit date:1995-10-12
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Second-site suppression of regulatory phosphorylation in Escherichia coli isocitrate dehydrogenase.
Protein Sci., 5, 1996
1GRP
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BU of 1grp by Molmil
REGULATORY AND CATALYTIC MECHANISMS IN ESCHERICHIA COLI ISOCITRATE DEHYDROGENASE: MULTIPLE ROLES FOR N115
Descriptor: ISOCITRATE DEHYDROGENASE, ISOCITRIC ACID, MAGNESIUM ION
Authors:Grobler, J.A, Hurley, J.H.
Deposit date:1995-10-12
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Second-site suppression of regulatory phosphorylation in Escherichia coli isocitrate dehydrogenase.
Protein Sci., 5, 1996
5DWW
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BU of 5dww by Molmil
Structural Insights into the Quadruplex-Duplex 3' Interface formed from a Telomeric Repeat - TTLOOP
Descriptor: DNA (25-MER), DNA (5'-D(*TP*AP*AP*CP*GP*CP*TP*A)-3'), POTASSIUM ION
Authors:Russo Krauss, I, Parkinson, G.N.
Deposit date:2015-09-23
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural Insights into the Quadruplex-Duplex 3' Interface Formed from a Telomeric Repeat: A Potential Molecular Target.
J.Am.Chem.Soc., 138, 2016
5W3C
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BU of 5w3c by Molmil
Crystal structure of mutant CJ YCEI protein (CJ-N182C) with selenocysteine guest structure
Descriptor: EICOSANE, Polyisoprenoid-binding protein, SELENOCYSTEINE, ...
Authors:Huber, T.R, Snow, C.D.
Deposit date:2017-06-07
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.
Bioconjug. Chem., 29, 2018

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数据于2024-07-17公开中

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