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1Z8Y
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Mapping the E2 Glycoprotein of Alphaviruses
Descriptor: Capsid protein C, Spike glycoprotein E1, Spike glycoprotein E2
Authors:Mukhopadhyay, S, Zhang, W, Gabler, S, Chipman, P.R, Strauss, E.G, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G.
Deposit date:2005-03-31
Release date:2006-02-07
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Mapping the structure and function of the E1 and E2 glycoproteins in alphaviruses.
Structure, 14, 2006
1ZL3
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Coupling of active site motions and RNA binding
Descriptor: 5'-R(*GP*GP*CP*AP*AP*CP*GP*GP*UP*(FLO) UP*CP*GP*AP*UP*CP*CP*CP*GP*UP*UP*GP*C)-3', SULFATE ION, tRNA pseudouridine synthase B
Authors:Hoang, C, Hamilton, C.S, Mueller, E.G, Ferre-D'Amare, A.R.
Deposit date:2005-05-05
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain
Protein Sci., 14, 2005
1ZA4
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Crystal Structure of the Thrombospondin-1 N-terminal Domain in Complex with Arixtra
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, SULFATE ION, Thrombospondin 1
Authors:Tan, K, Wang, J.H, Lawler, J.
Deposit date:2005-04-05
Release date:2006-01-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Structures of the Thrombospondin-1 N-terminal Domain and its Complex with a Synthetic Pentameric Heparin
Structure, 14, 2006
2GWL
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Crystal structure of the Salmonella SpvB ATR Domain in complex with NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 65 kDa virulence protein
Authors:Stebbins, C.E, Margarit, S.M.
Deposit date:2006-05-04
Release date:2006-08-29
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A steric antagonism of actin polymerization by a salmonella virulence protein.
Structure, 14, 2006
2GZD
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Crystal Structure of Rab11 in Complex with Rab11-FIP2
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab11 family-interacting protein 2, ...
Authors:Khan, A.R.
Deposit date:2006-05-11
Release date:2006-08-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal structure of rab11 in complex with rab11 family interacting protein 2.
Structure, 14, 2006
2H59
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Sir2 H116A-deacetylated p53 peptide-3'-o-acetyl ADP ribose
Descriptor: (2S,3S,4R,5S)-2-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-4,5-DIHYDROXYTETRAHYDROFURAN-3-YL ACETATE, ADENOSINE-5-DIPHOSPHORIBOSE, Cellular tumor antigen p53, ...
Authors:Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C.
Deposit date:2006-05-25
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide.
Structure, 14, 2006
2H8L
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Crystal structure of the bb' fragment of ERp57
Descriptor: Protein disulfide-isomerase A3
Authors:Kozlov, G, Schrag, J.D, Cygler, M, Gehring, K.
Deposit date:2006-06-07
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the bb' Domains of the Protein Disulfide Isomerase ERp57.
Structure, 14, 2006
1ZMW
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Catalytic and ubiqutin-associated domains of MARK2/PAR-1: T208A/S212A inactive double mutant
Descriptor: MAP/Microtubule affinity regulating kinase 2
Authors:Panneerselvam, S, Marx, A, Mandelkow, E.-M, Mandelkow, E.
Deposit date:2005-05-11
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Structure of the catalytic and ubiquitin-associated domains of the protein kinase MARK/Par-1.
Structure, 14, 2006
2F9T
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Structure of the type III CoaA from Pseudomonas aeruginosa
Descriptor: Pantothenate Kinase
Authors:Leonardi, R, Yun, M.K, Chohnan, S, White, S.W, Rock, C.O, Jackowski, S.
Deposit date:2005-12-06
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Prokaryotic Type II and Type III Pantothenate Kinases: The Same Monomer Fold Creates Dimers with Distinct Catalytic Properties.
Structure, 14, 2006
2FLP
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Binary complex of the catalytic core of human DNA polymerase iota with DNA (template G)
Descriptor: DNA polymerase iota, DNA primer strand, DNA template strand
Authors:Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K.
Deposit date:2006-01-06
Release date:2006-12-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site.
Structure, 14, 2006
1SQA
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Substituted 2-Naphthamidine Inhibitors of Urokinase
Descriptor: 6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-4-(PYRIMIDIN-2-YLAMINO)-2-NAPHTHAMIDE, SULFATE ION, Urokinase-type plasminogen activator
Authors:Wendt, M.D, Geyer, A, McClellan, W.J, Rockway, T.W, Weitzberg, M, Zhao, X, Stewart, K, Nienaber, V, Klinghofer, V, Giranda, V.L.
Deposit date:2004-03-18
Release date:2004-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interaction with the S1beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
2EUW
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Structure of a Ndt80-DNA complex (MSE mutant mA4T)
Descriptor: 5'-D(*AP*GP*TP*TP*TP*TP*TP*GP*AP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*TP*CP*AP*AP*AP*AP*AP*C)-3', NDT80 protein
Authors:Lamoureux, J.S, Glover, J.N.
Deposit date:2005-10-30
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes.
Structure, 14, 2006
2EYV
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BU of 2eyv by Molmil
SH2 domain of CT10-Regulated Kinase
Descriptor: v-crk sarcoma virus CT10 oncogene homolog isoform a
Authors:Kobashigawa, Y, Tanaka, S, Inagaki, F.
Deposit date:2005-11-10
Release date:2006-11-10
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.
Nat.Struct.Mol.Biol., 14, 2007
2F3Q
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Crystal structure of the glycogen phosphorylase B / methyl-N-(beta-D-glucopyranosyl)oxamate complex
Descriptor: Glycogen phosphorylase, muscle form, N-[methoxy(oxo)acetyl]-beta-D-glucopyranosylamine, ...
Authors:Oikonomakos, N.G, Leonidas, D.D.
Deposit date:2005-11-22
Release date:2006-05-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Binding of oxalyl derivatives of beta-d-glucopyranosylamine to muscle glycogen phosphorylase b.
Bioorg.Med.Chem., 14, 2006
2C3K
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Identification of a buried pocket for potent and selective inhibition of Chk1: prediction and verification
Descriptor: 4-[3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOL-6-YL]-2-METHOXYPHENOL, SERINE/THREONINE-PROTEIN KINASE CHK1
Authors:Foloppe, N, Fisher, L.M, Francis, G, Howes, R, Kierstan, P, Potter, A.
Deposit date:2005-10-10
Release date:2005-11-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Identification of a Buried Pocket for Potent and Selective Inhibition of Chk1: Prediction and Verification.
Bioorg.Med.Chem., 14, 2006
2EYW
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N-terminal SH3 domain of CT10-Regulated Kinase
Descriptor: v-crk sarcoma virus CT10 oncogene homolog isoform a
Authors:Kobashigawa, Y, Tanaka, S, Inagaki, F.
Deposit date:2005-11-10
Release date:2006-11-10
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK.
Nat.Struct.Mol.Biol., 14, 2007
2C43
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STRUCTURE OF AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE- PHOSPHOPANTETHEINYL TRANSFERASE IN COMPLEX WITH COENZYME A
Descriptor: AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE, CHLORIDE ION, COENZYME A, ...
Authors:Bunkoczi, G, Wu, X, Dubinina, E, Johansson, C, Smee, C, Turnbull, A, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Oppermann, U.
Deposit date:2005-10-14
Release date:2005-10-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Mechanism and substrate recognition of human holo ACP synthase.
Chem. Biol., 14, 2007
2FF3
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Crystal structure of Gelsolin domain 1:N-wasp V2 motif hybrid in complex with actin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Xue, B, Aguda, A.H, Robinson, R.C.
Deposit date:2005-12-19
Release date:2006-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structural Basis of Actin Interaction with Multiple WH2/beta-Thymosin Motif-Containing Proteins
Structure, 14, 2006
2C1V
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BU of 2c1v by Molmil
CRYSTAL STRUCTURE OF THE DI-HAEM CYTOCHROME C PEROXIDASE FROM PARACOCCUS PANTOTROPHUS - Mixed VALENCE FORM
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DI-HAEM CYTOCHROME C PEROXIDASE, ...
Authors:Echalier, A, Fulop, V.
Deposit date:2005-09-21
Release date:2006-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Activation and Catalysis of the Di-Heme Cytochrome C Peroxidase from Paracoccus Pantotrophus
Structure, 14, 2006
2C3J
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Identification of a buried pocket for potent and selective inhibition of Chk1: prediction and verification
Descriptor: DEBROMOHYMENIALDISINE, SERINE/THREONINE-PROTEIN KINASE CHK1, SULFITE ION
Authors:Foloppe, N, Fisher, L.M, Francis, G, Howes, R, Kierstan, P, Potter, A.
Deposit date:2005-10-10
Release date:2005-11-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of a Buried Pocket for Potent and Selective Inhibition of Chk1: Prediction and Verification.
Bioorg.Med.Chem., 14, 2006
2F8S
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BU of 2f8s by Molmil
Crystal structure of Aa-Ago with externally-bound siRNA
Descriptor: 5'-R(P*AP*GP*AP*CP*AP*GP*CP*AP*UP*AP*UP*AP*UP*GP*CP*UP*GP*UP*CP*UP*UP*U)-3', Argonaute protein
Authors:Yuan, Y.R, Chen, H.Y, Patel, D.J.
Deposit date:2005-12-03
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Potential Protein-RNA Recognition Event along the RISC-Loading Pathway from the Structure of A. aeolicus Argonaute with Externally Bound siRNA.
Structure, 14, 2006
2BQ5
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MS2 (N87AE89K mutant) - RNA hairpin complex
Descriptor: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *UP*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN
Authors:Horn, W.T, Tars, K, Grahn, E, Helgstrand, C, Baron, A.J, Lago, H, Adams, C.J, Peabody, D.S, Phillips, S.E.V, Stonehouse, N.J, Liljas, L, Stockley, P.G.
Deposit date:2005-04-27
Release date:2006-03-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structural Basis of RNA Binding Discrimination between Bacteriophages Qbeta and MS2.
Structure, 14, 2006
2HD5
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USP2 in complex with ubiquitin
Descriptor: Polyubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ZINC ION
Authors:Renatus, M, Kroemer, M.
Deposit date:2006-06-20
Release date:2006-08-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis of Ubiquitin Recognition by the Deubiquitinating Protease USP2.
Structure, 14, 2006
2HEY
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BU of 2hey by Molmil
Crystal structure of murine OX40L bound to human OX40
Descriptor: SULFATE ION, Tumor necrosis factor ligand superfamily member 4, Tumor necrosis factor receptor superfamily member 4
Authors:Hymowitz, S.G.
Deposit date:2006-06-22
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of the Costimulatory OX40-OX40L Complex.
Structure, 14, 2006
2GMO
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NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2
Descriptor: Polymerase basic protein 2
Authors:Boudet, J, Tarendeau, F, Guilligay, D, Mas, P, Bougault, C.M, Cusack, S, Simorre, J.-P, Hart, D.J.
Deposit date:2006-04-07
Release date:2007-02-27
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.
Nat.Struct.Mol.Biol., 14, 2007

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数据于2024-09-11公开中

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