PDB: 13252 resultsInfo pagesStatus searchChemie searchBIRD

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1HKN	A complex between acidic fibroblast growth factor and 5-amino-2-naphthalenesulfonate Descriptor: 5-AMINO-NAPHTALENE-2-MONOSULFONATE, HEPARIN-BINDING GROWTH FACTOR 1 Authors: Fernandez-Tornero, C, Lozano, R.M, Gimenez-Gallego, G, Romero, A. Deposit date: 2003-03-10 Release date: 2004-03-11 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate J.Biol.Chem., 278, 2003
4K0R	Crystal structure of mouse Cryptochrome 1 Descriptor: Cryptochrome-1 Authors: Czarna, A, Wolf, E. Deposit date: 2013-04-04 Release date: 2013-06-26 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function. Cell(Cambridge,Mass.), 153, 2013
2MAO	NMR structure of region 2 of E. coli sigmaE Descriptor: RNA polymerase sigma factor Authors: Campagne, S, Vorholt, J.A, Allain, F.H.-T. Deposit date: 2013-07-16 Release date: 2014-02-19 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural basis for -10 promoter element melting by environmentally induced sigma factors. Nat.Struct.Mol.Biol., 21, 2014
1AJL	FIVE-NUCLEOTIDE BULGE LOOP FROM TETRAHYMENA THERMOPHILA GROUP I INTRON Descriptor: RNA (5'-R(*GP*AP*GP*UP*AP*CP*C)-3'), RNA (5'-R(*GP*GP*UP*AP*AP*UP*AP*AP*GP*CP*UP*C)-3') Authors: Luebke, K.J, Landry, S.M, Tinoco Junior, I. Deposit date: 1997-05-06 Release date: 1997-07-07 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Solution conformation of a five-nucleotide RNA bulge loop from a group I intron. Biochemistry, 36, 1997
3G6Y	Ternary complex of DNA Polymerase iota:DNA:dTTP with an abasic site at the templating position Descriptor: DNA polymerase iota, MAGNESIUM ION, Primer DNA strand, ... Authors: Nair, D.T, Aggarwal, A.K. Deposit date: 2009-02-09 Release date: 2009-05-12 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: DNA Synthesis across an Abasic Lesion by Human DNA Polymerase iota Structure, 17, 2009
3G6X	Ternary complex of DNA Polymerase iota:DNA:dGTP with an abasic site at the templating position Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase iota, MAGNESIUM ION, ... Authors: Nair, D.T, Aggarwal, A.K. Deposit date: 2009-02-09 Release date: 2009-05-12 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.08 Å) Cite: DNA Synthesis across an Abasic Lesion by Human DNA Polymerase iota. Structure, 17, 2009
1QFW	TERNARY COMPLEX OF HUMAN CHORIONIC GONADOTROPIN WITH FV ANTI ALPHA SUBUNIT AND FV ANTI BETA SUBUNIT Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (ANTI ALPHA SUBUNIT) (HEAVY CHAIN), ANTIBODY (ANTI ALPHA SUBUNIT) (LIGHT CHAIN), ... Authors: Tegoni, M, Spinelli, S, Cambillau, C. Deposit date: 1999-04-15 Release date: 2000-04-26 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits. J.Mol.Biol., 289, 1999
2OH2	Ternary Complex of Human DNA Polymerase Descriptor: 5'-D(*GP*GP*G*GP*GP*AP*AP*GP*GP*AP*CP*CP*C)-3', 5'-D(*TP*T*CP*CP*AP*GP*GP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', DNA polymerase kappa, ... Authors: Lone, S, Townson, S.A, Uljon, S.N, Prakash, S, Prakash, L, Aggarwal, A.K. Deposit date: 2007-01-09 Release date: 2007-02-27 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.05 Å) Cite: Ternary complex of the catalytic core of human DNA polymerase Kappa with DNA and dTT To be Published
3QLM	Crystal structure of porcine pancreatic phospholipase A2 in complex with n-hexadecanoic acid Descriptor: CALCIUM ION, PALMITIC ACID, Phospholipase A2, ... Authors: Aparna, V, Dileep, K.V, Karthe, P, Mandal, P.K, Sadasivan, C, Haridas, M. Deposit date: 2011-02-03 Release date: 2011-04-06 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Anti-inflammatory property of n-hexadecanoic acid: Structural evidence and Kinetic assessment. Chem.Biol.Drug Des., 2012
5VU5	TNA polymerase, apo Descriptor: DNA polymerase Authors: Chim, N, Chaput, J.C. Deposit date: 2017-05-18 Release date: 2017-12-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
8A40	Structure of mammalian Pol II-TFIIS elongation complex Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P. Deposit date: 2022-06-09 Release date: 2023-08-23 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structure of a backtracked hexasomal intermediate of nucleosome transcription. Mol.Cell, 82, 2022
8Y7M	FluPol-NS2 complex (local refinement) Descriptor: Nuclear export protein, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Peng, Q, Sun, J.Q. Deposit date: 2024-02-04 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (3 Å) Cite: NS2 stabilizes polymerase hexamer to regulate transcription-replication switch of influenza A virus To Be Published
8Y7O	FluPol-NS2 complex (hexamer) Descriptor: Nuclear export protein, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Peng, Q, Sun, J.Q. Deposit date: 2024-02-04 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (3 Å) Cite: NS2 stabilizes polymerase hexamer to regulate transcription-replication switch of influenza A virus To Be Published
2HZM	Structure of the Mediator head subcomplex Med18/20 Descriptor: PHOSPHATE ION, RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20 Authors: Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P. Deposit date: 2006-08-09 Release date: 2006-09-12 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20. Nat.Struct.Mol.Biol., 13, 2006
4WC5	Structure of tRNA-processing enzyme complex 3 Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Poly A polymerase, RNA (74-MER) Authors: Yamashita, S, Tomita, K. Deposit date: 2014-09-04 Release date: 2015-04-15 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.41 Å) Cite: Measurement of Acceptor-T Psi C Helix Length of tRNA for Terminal A76-Addition by A-Adding Enzyme. Structure, 23, 2015
4IH7	Hepatitis C Virus polymerase NS5B (BK) with fragment-based compounds Descriptor: 3-(3-tert-butylphenyl)pyridin-2(1H)-one, RNA-directed RNA polymerase, ZINC ION Authors: Harris, S.F, Wong, A. Deposit date: 2012-12-18 Release date: 2013-07-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: De novo fragment design: a medicinal chemistry approach to fragment-based lead generation. J.Med.Chem., 56, 2013
4IH5	Hepatitis C Virus polymerase NS5B (BK) with fragment-based compounds Descriptor: 4-(2-phenylhydrazinyl)-1H-pyrazolo[3,4-d]pyrimidine, RNA-directed RNA polymerase Authors: Harris, S.F, Ghate, M. Deposit date: 2012-12-18 Release date: 2013-07-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: De novo fragment design: a medicinal chemistry approach to fragment-based lead generation. J.Med.Chem., 56, 2013
4IH6	Hepatitis C Virus polymerase NS5B (BK) with fragment-based compounds Descriptor: (5S)-3-(4-tert-butylbenzyl)-5-(propan-2-yl)imidazolidine-2,4-dione, RNA-directed RNA polymerase Authors: Harris, S.F, Wong, A. Deposit date: 2012-12-18 Release date: 2013-07-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.2 Å) Cite: De novo fragment design: a medicinal chemistry approach to fragment-based lead generation. J.Med.Chem., 56, 2013
1JO7	Solution Structure of Influenza A Virus Promoter Descriptor: Influenza A virus promoter RNA Authors: Bae, S.-H, Cheong, H.-K, Lee, J.-H, Cheong, C, Kainosho, M, Choi, B.-S. Deposit date: 2001-07-27 Release date: 2001-09-19 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural features of an influenza virus promoter and their implications for viral RNA synthesis. Proc.Natl.Acad.Sci.USA, 98, 2001
8I23	Clostridium thermocellum RNA polymerase transcription open complex with SigI1 and its promoter Descriptor: DNA (80-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Li, J, Zhang, H, Li, D, Feng, Y, Zhu, P. Deposit date: 2023-01-13 Release date: 2023-10-11 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.03 Å) Cite: Structure of the transcription open complex of distinct sigma I factors. Nat Commun, 14, 2023
8I24	Clostridium thermocellum RNA polymerase transcription open complex with SigI6 and its promoter Descriptor: DNA (80-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Li, J, Zhang, H, Li, D, Feng, Y, Zhu, P. Deposit date: 2023-01-13 Release date: 2023-10-11 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (3.36 Å) Cite: Structure of the transcription open complex of distinct sigma I factors. Nat Commun, 14, 2023
6CFP	CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE Descriptor: 1-{1-[(4-fluorophenyl)methyl]-2-methyl-1H-imidazol-4-yl}ethan-1-one, DIMETHYL SULFOXIDE, Ubiquitin-like protein SMT3,Polymerase acidic protein Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-02-15 Release date: 2018-04-11 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.45 Å) Cite: CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE To Be Published
3EBJ	Crystal structure of an avian influenza virus protein Descriptor: MAGNESIUM ION, Polymerase acidic protein Authors: Yuan, P, Bartlam, M, Lou, Z, Chen, S, Rao, Z, Liu, Y. Deposit date: 2008-08-27 Release date: 2009-02-10 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site Nature, 458, 2009
7ZIU	Crystal structure of Ntaya virus NS5 polymerase domain Descriptor: Genome polyprotein, ZINC ION Authors: Krejcova, K, Klima, M, Boura, E. Deposit date: 2022-04-08 Release date: 2023-04-19 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural and functional insights in flavivirus NS5 proteins gained by the structure of Ntaya virus polymerase and methyltransferase. Structure, 2024
1TK8	T7 DNA polymerase ternary complex with 8 oxo guanosine and dAMP at the elongation site Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*AP*(8OG)P*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', ... Authors: Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. Deposit date: 2004-06-08 Release date: 2004-08-31 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Embo J., 23, 2004

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