Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5KSI
DownloadVisualize
BU of 5ksi by Molmil
Crystal structure of deoxygenated hemoglobin in complex with sphingosine phosphate and 2,3-Bisphosphoglycerate
Descriptor: (2R)-2,3-diphosphoglyceric acid, (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Hemoglobin subunit alpha, ...
Authors:Ahmed, M.H, Safo, M.K, Xia, Y.
Deposit date:2016-07-08
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease.
Sci Rep, 7, 2017
5HJ0
DownloadVisualize
BU of 5hj0 by Molmil
Crystal Structure of Mis18 'Yippee-like' Domain
Descriptor: Kinetochore protein mis18, ZINC ION
Authors:Medina-Pritchard, B, Subramanian, L, Allshire, R, Arockia Jeyaprakash, A.
Deposit date:2016-01-12
Release date:2016-03-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerization.
Embo Rep., 17, 2016
6AYN
DownloadVisualize
BU of 6ayn by Molmil
Structure of cetuximab with aminoheptanoic acid-linked N-(3-aminopropyl)-L-arginine meditope variant
Descriptor: Cetuximab Fab heavy chain, Cetuximab Fab light chain, Cyclic meditope
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2017-09-08
Release date:2017-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6AZK
DownloadVisualize
BU of 6azk by Molmil
Structure of cetuximab with aminoheptanoic acid-linked N-(3-hydroxypropyl)-L-arginine meditope variant
Descriptor: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2017-09-11
Release date:2017-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.477 Å)
Cite:Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6AXP
DownloadVisualize
BU of 6axp by Molmil
Structure of cetuximab with aminoheptanoic acid-linked n-octylarginine meditope variant
Descriptor: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2017-09-07
Release date:2017-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.484 Å)
Cite:Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6AU5
DownloadVisualize
BU of 6au5 by Molmil
Structure of cetuximab with aminoheptanoic acid-linked n-butylarginine meditope variant
Descriptor: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2017-08-30
Release date:2017-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.484 Å)
Cite:Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6AZL
DownloadVisualize
BU of 6azl by Molmil
Structure of cetuximab with aminoheptanoic acid-linked N-carboxyethylarginine meditope variant
Descriptor: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ...
Authors:Bzymek, K.P, Williams, J.C.
Deposit date:2017-09-11
Release date:2017-12-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.482 Å)
Cite:Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
6W1S
DownloadVisualize
BU of 6w1s by Molmil
Atomic model of the mammalian Mediator complex
Descriptor: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
Authors:Zhao, H, Young, N, Asturias, F.
Deposit date:2020-03-04
Release date:2021-03-10
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers.
Cell, 178, 2019
4QMD
DownloadVisualize
BU of 4qmd by Molmil
Crystal structure of human envoplakin plakin repeat domain
Descriptor: Envoplakin
Authors:Mohammed, F, Al-Jassar, C, White, S.A, Fogl, C, Jeeves, M, Knowles, T.J, Odinstova, E, Rodriguez-Zamora, P, Overduin, M, Chidgey, M.
Deposit date:2014-06-16
Release date:2015-07-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin.
Nat Commun, 7, 2016
3V5M
DownloadVisualize
BU of 3v5m by Molmil
Crystal structure of M69V mutant of SHV beta-lactamase
Descriptor: Beta-lactamase, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE
Authors:van den Akker, F, Rodkey, E.A.
Deposit date:2011-12-16
Release date:2012-08-08
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The importance of the trans-enamine intermediate as a beta-lactamase inhibition strategy probed in inhibitor-resistant SHV beta-lactamase variants.
Chemmedchem, 7, 2012
3V50
DownloadVisualize
BU of 3v50 by Molmil
Complex of SHV S130G mutant beta-lactamase complexed to SA2-13
Descriptor: (3R)-4-[(4-CARBOXYBUTANOYL)OXY]-N-[(1E)-3-OXOPROP-1-EN-1-YL]-3-SULFINO-D-VALINE, Beta-lactamase, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE
Authors:Wei, K, van den Akker, F.
Deposit date:2011-12-15
Release date:2012-08-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The importance of the trans-enamine intermediate as a beta-lactamase inhibition strategy probed in inhibitor-resistant SHV beta-lactamase variants.
Chemmedchem, 7, 2012
4H62
DownloadVisualize
BU of 4h62 by Molmil
Structure of the Saccharomyces cerevisiae Mediator subcomplex Med17C/Med11C/Med22C
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, ...
Authors:Lariviere, L, Plaschka, C, Seizl, M, Wenzeck, L, Kurth, F, Cramer, P.
Deposit date:2012-09-19
Release date:2012-10-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Mediator head module.
Nature, 492, 2012
6XP5
DownloadVisualize
BU of 6xp5 by Molmil
Head-Middle module of Mediator
Descriptor: HEAT, Med22, Mediator of RNA polymerase II transcription subunit 1, ...
Authors:Zhang, H.Q, Chen, D.C, Kornberg, R.D.
Deposit date:2020-07-08
Release date:2021-03-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Mediator structure and conformation change.
Mol.Cell, 81, 2021
4GWQ
DownloadVisualize
BU of 4gwq by Molmil
Structure of the Mediator Head Module from S. cerevisiae in complex with the carboxy-terminal domain (CTD) of RNA Polymerase II Rpb1 subunit
Descriptor: DNA-directed RNA polymerase II subunit RPB1, Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, ...
Authors:Robinson, P.J.J, Bushnell, D.A, Trnka, M.J, Burlingame, A.L, Kornberg, R.D.
Deposit date:2012-09-03
Release date:2012-10-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II.
Proc.Natl.Acad.Sci.USA, 109, 2012
2HZS
DownloadVisualize
BU of 2hzs by Molmil
Structure of the Mediator head submodule Med8C/18/20
Descriptor: RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20, RNA polymerase II mediator complex subunit 8
Authors:Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P.
Deposit date:2006-08-09
Release date:2006-09-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006
2HZM
DownloadVisualize
BU of 2hzm by Molmil
Structure of the Mediator head subcomplex Med18/20
Descriptor: PHOSPHATE ION, RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20
Authors:Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P.
Deposit date:2006-08-09
Release date:2006-09-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006
2P4H
DownloadVisualize
BU of 2p4h by Molmil
Crystal Structure of Vestitone Reductase from Alfalfa (Medicago sativa L.)
Descriptor: Vestitone reductase
Authors:Wang, X, Shao, H, Dixon, R.A.
Deposit date:2007-03-12
Release date:2007-05-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of Vestitone Reductase from Alfalfa (Medicago sativa L.).
J.Mol.Biol., 369, 2007
2PQ6
DownloadVisualize
BU of 2pq6 by Molmil
Crystal structure of Medicago truncatula UGT85H2- Insights into the structural basis of a multifunctional (Iso) flavonoid glycosyltransferase
Descriptor: UDP-glucuronosyl/UDP-glucosyltransferase
Authors:Li, L, Modolo, L.V, Escamilla-Trevino, L.L, Wang, X.
Deposit date:2007-05-01
Release date:2007-07-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Medicago truncatula UGT85H2 - Insights into the Structural Basis of a Multifunctional (Iso)flavonoid Glycosyltransferase.
J.Mol.Biol., 370, 2007
6H02
DownloadVisualize
BU of 6h02 by Molmil
Crystal structure of human Mediator subunit MED23
Descriptor: LAMA nanobody NB106, Mediator of RNA polymerase II transcription subunit 23
Authors:Clantin, B, Monte, D, Villeret, V.
Deposit date:2018-07-06
Release date:2018-08-29
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human Mediator subunit MED23.
Nat Commun, 9, 2018
2ACV
DownloadVisualize
BU of 2acv by Molmil
Crystal Structure of Medicago truncatula UGT71G1
Descriptor: URIDINE-5'-DIPHOSPHATE, triterpene UDP-glucosyl transferase UGT71G1
Authors:Shao, H, He, X, Achnine, L, Blount, J.W, Dixon, R.A, Wang, X.
Deposit date:2005-07-19
Release date:2005-11-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of a Multifunctional Triterpene/Flavonoid Glycosyltransferase from Medicago truncatula.
Plant Cell, 17, 2005
1YKE
DownloadVisualize
BU of 1yke by Molmil
Structure of the mediator MED7/MED21 subcomplex
Descriptor: RNA polymerase II holoenzyme component SRB7, RNA polymerase II mediator complex protein MED7
Authors:Baumli, S, Hoeppner, S, Cramer, P.
Deposit date:2005-01-18
Release date:2005-02-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A conserved mediator hinge revealed in the structure of the MED7.MED21 (Med7.Srb7) heterodimer.
J.Biol.Chem., 280, 2005
1YKH
DownloadVisualize
BU of 1ykh by Molmil
Structure of the mediator MED7/MED21 (Med7/Srb7) subcomplex
Descriptor: RNA polymerase II holoenzyme component SRB7, RNA polymerase II mediator complex protein MED7
Authors:Baumli, S, Hoeppner, S, Cramer, P.
Deposit date:2005-01-18
Release date:2005-02-22
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:A conserved mediator hinge revealed in the structure of the MED7.MED21 (Med7.Srb7) heterodimer.
J.Biol.Chem., 280, 2005
2ACW
DownloadVisualize
BU of 2acw by Molmil
Crystal Structure of Medicago truncatula UGT71G1 complexed with UDP-glucose
Descriptor: URIDINE-5'-DIPHOSPHATE-GLUCOSE, triterpene UDP-glucosyl transferase UGT71G1
Authors:Shao, H, He, X, Achnine, L, Blount, J.W, Dixon, R.A, Wang, X.
Deposit date:2005-07-19
Release date:2005-11-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of a Multifunctional Triterpene/Flavonoid Glycosyltransferase from Medicago truncatula.
Plant Cell, 17, 2005
1I76
DownloadVisualize
BU of 1i76 by Molmil
COMPLEX OF 2-(BIPHENYL-4-SULFONYL)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID (D-TIC DERIVATIVE) WITH T CATALITIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM)
Descriptor: 2-(BIPHENYL-4-SULFONYL)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID, CALCIUM ION, NEUTROPHIL COLLAGENASE, ...
Authors:Gavuzzo, E, Pochetti, G, Mazza, F, Gallina, C, Gorini, B, D'Alessio, S, Pieper, M, Tschesche, H, Tucker, P.A.
Deposit date:2001-03-08
Release date:2001-03-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design.
J.Med.Chem., 43, 2000
1I73
DownloadVisualize
BU of 1i73 by Molmil
COMPLEX OF PRO-LEU-L-TRP PHOSPHONATE WITH THE CATALITIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM)
Descriptor: CALCIUM ION, NEUTROPHIL COLLAGENASE, THREE RESIDUE PEPTIDE INHIBITOR, ...
Authors:Gavuzzo, E, Pochetti, G, Mazza, F, Gallina, C, Gorini, B, D'Alessio, S, Pieper, M, Tschesche, H, Tucker, P.A.
Deposit date:2001-03-07
Release date:2001-03-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design.
J.Med.Chem., 43, 2000

221716

数据于2024-06-26公开中

PDB statisticsPDBj update infoContact PDBjnumon