7TNF
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7TNU
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1HXM
| Crystal Structure of a Human Vgamma9/Vdelta2 T Cell Receptor | Descriptor: | GAMMA-DELTA T-CELL RECEPTOR, SULFATE ION | Authors: | Allison, T.J, Winter, C.C, Fournie, J.J, Bonneville, M, Garboczi, D.N. | Deposit date: | 2001-01-16 | Release date: | 2001-06-20 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | Structure of a human gammadelta T-cell antigen receptor. Nature, 411, 2001
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6ZSA
| Human mitochondrial ribosome bound to mRNA, A-site tRNA and P-site tRNA | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Aibara, S, Singh, V, Modelska, A, Amunts, A. | Deposit date: | 2020-07-15 | Release date: | 2020-10-21 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of mitochondrial translation. Elife, 9, 2020
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4XG2
| Crystal structure of ligand-free Syk | Descriptor: | Tyrosine-protein kinase SYK | Authors: | Lee, S.J, Choi, J, Han, B.G, Song, H, Koh, J.S, Lee, B.I. | Deposit date: | 2014-12-30 | Release date: | 2015-12-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs Febs J., 283, 2016
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4MIM
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4MJ5
| Crystal Structure of HLA-A*1101 in complex with H1-22, an influenza A(H1N1) virus epitope | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-11 alpha chain, ... | Authors: | Liu, J, Tan, S, Zhao, M, Qi, J, Gao, G.F. | Deposit date: | 2013-09-03 | Release date: | 2014-10-08 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Cross-immunity Against Avian Influenza A(H7N9) Virus in the Healthy Population Is Affected by Antigenicity-Dependent Substitutions. J.Infect.Dis., 214, 2016
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4QGZ
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4MJ6
| Crystal Structure of HLA-A*1101 in complex with H7-22, an influenza A(H7N9) virus epitope | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-11 alpha chain, ... | Authors: | Liu, J, Tan, S, Zhao, M, Qi, J, Gao, G.F. | Deposit date: | 2013-09-03 | Release date: | 2014-10-08 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Cross-immunity Against Avian Influenza A(H7N9) Virus in the Healthy Population Is Affected by Antigenicity-Dependent Substitutions. J.Infect.Dis., 214, 2016
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4MJH
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4MR3
| Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolinone ligand (RVX-OH) | Descriptor: | 1,2-ETHANEDIOL, 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxyquinazolin-4(3H)-one, Bromodomain-containing protein 4 | Authors: | Filippakopoulos, P, Picaud, S, Felletar, I, Martin, S, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2013-09-17 | Release date: | 2013-11-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain. Proc.Natl.Acad.Sci.USA, 110, 2013
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4MR5
| Crystal Structure of the second bromodomain of human BRD2 in complex with a quinazolinone ligand (RVX-OH) | Descriptor: | 1,2-ETHANEDIOL, 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxyquinazolin-4(3H)-one, Bromodomain-containing protein 2, ... | Authors: | Filippakopoulos, P, Picaud, S, Felletar, I, Martin, S, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2013-09-17 | Release date: | 2013-11-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain. Proc.Natl.Acad.Sci.USA, 110, 2013
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1WTG
| Human Factor Viia-Tissue Factor Complexed with ethylsulfonamide-D-biphenylalanine-Gln-p-aminobenzamidine | Descriptor: | 2-(3-BIPHENYL-4-YL-2-ETHANESULFONYLAMINO-PROPIONYLAMINO)-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE), CALCIUM ION, Coagulation factor VII, ... | Authors: | Kadono, S, Sakamoto, S, Kikuchi, Y, Oh-Eda, M, Yabuta, N, Kitazawa, K, Yoshihashi, T, Suzuki, T, Koga, T, Hattori, K, Shiraishi, T, Kodama, M, Haramura, H, Ono, Y, Esaki, T, Sato, H, Watanabe, Y, Itoh, S, Ohta, M, Kozono, T. | Deposit date: | 2004-11-23 | Release date: | 2005-11-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Novel interactions of large P3 moiety and small P4 moiety in the binding of the peptide mimetic factor VIIa inhibitor Biochem.Biophys.Res.Commun., 326, 2005
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2RLA
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2YHD
| Human androgen receptor in complex with AF2 small molecule inhibitor | Descriptor: | 4-(2,3-dihydro-1H-perimidin-2-yl)benzene-1,2-diol, ANDROGEN RECEPTOR, SULFATE ION, ... | Authors: | AxerioCilies, P, Lack, N.A, ShashiNayana, M.R, Chan, K.H, Yeung, A, LeBlanc, E, Guns, E, Rennie, P, Cherkasov, A. | Deposit date: | 2011-04-28 | Release date: | 2011-09-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Inhibitors of Androgen Receptor Activation Function-2 (Af2) Site Identified Through Virtual Screening. J.Med.Chem., 54, 2011
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3OZV
| The Crystal Structure of flavohemoglobin from R. eutrophus in complex with econazole | Descriptor: | 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE, 1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | El Hammi, E, Warkentin, E, Demmer, U, Ermler, U, Baciou, L. | Deposit date: | 2010-09-27 | Release date: | 2011-03-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of Ralstonia eutropha Flavohemoglobin in Complex with Three Antibiotic Azole Compounds. Biochemistry, 50, 2011
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2BJA
| Crystal Analysis of 1-Pyrroline-5-Carboxylate Dehydrogenase from Thermus with bound NADH | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, ... | Authors: | Inagaki, E, Tahirov, T.H. | Deposit date: | 2005-02-01 | Release date: | 2006-03-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Thermus Thermophilus Delta1-Pyrroline-5-Carboxylate Dehydrogenase. J.Mol.Biol., 362, 2006
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2HLE
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8DWT
| SPOP W22R Form 2 | Descriptor: | Speckle-type POZ protein | Authors: | Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H. | Deposit date: | 2022-08-02 | Release date: | 2023-01-18 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation. Mol.Cell, 83, 2023
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8DWV
| Full-length wild type SPOP | Descriptor: | Speckle-type POZ protein | Authors: | Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H. | Deposit date: | 2022-08-02 | Release date: | 2023-01-18 | Last modified: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation. Mol.Cell, 83, 2023
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8DWS
| Full-length E47K SPOP | Descriptor: | Speckle-type POZ protein | Authors: | Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H. | Deposit date: | 2022-08-02 | Release date: | 2023-01-18 | Last modified: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation. Mol.Cell, 83, 2023
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8DWU
| SPOP W22R Form 1 | Descriptor: | Speckle-type POZ protein | Authors: | Cuneo, M.J, Mittag, T, O'Flynn, B. | Deposit date: | 2022-08-02 | Release date: | 2023-01-18 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation. Mol.Cell, 83, 2023
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6AJ5
| Crystal structure of ligand-free type DHODH from Eimeria tenella | Descriptor: | Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... | Authors: | Shiba, T, Inaoka, D.K, Sato, D, Hartuti, E.D, Amalia, E, Nagahama, M, Yoshioka, Y, Matsubayashi, M, Balogun, E.O, Tsuji, N, Kita, K, Harada, S. | Deposit date: | 2018-08-27 | Release date: | 2019-08-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target. Genes (Basel), 11, 2020
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5FBP
| CRYSTAL STRUCTURE OF THE NEUTRAL FORM OF FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH THE PRODUCT FRUCTOSE 6-PHOSPHATE AT 2.1-ANGSTROMS RESOLUTION | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, FRUCTOSE 1,6-BISPHOSPHATASE | Authors: | Ke, H, Liang, J.-Y, Zhang, Y, Lipscomb, W.N. | Deposit date: | 1991-02-11 | Release date: | 1992-07-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the neutral form of fructose-1,6-bisphosphatase complexed with the product fructose 6-phosphate at 2.1-A resolution. Proc.Natl.Acad.Sci.USA, 88, 1991
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5FXJ
| GluN1b-GluN2B NMDA receptor structure-Class X | Descriptor: | GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1, NMDA 2B | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa H, H. | Deposit date: | 2016-03-02 | Release date: | 2016-05-25 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.25 Å) | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil. Nature, 534, 2016
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