6M14
 
 | | Crystal Structure of the BARD1 BRCT Mutant | | Descriptor: | BRCA1-associated RING domain protein 1, SULFATE ION | | Authors: | Chen, T, Huang, W.T. | | Deposit date: | 2020-02-24 | | Release date: | 2021-02-24 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.88001835 Å) | | Cite: | BARD1 is an ATPase activating protein for OLA1.
Biochim Biophys Acta Gen Subj, 1866, 2022
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2NTE
 | | Crystal Structure of the BARD1 BRCT Domains | | Descriptor: | 1,2-ETHANEDIOL, BRCA1-associated RING domain protein 1, CHLORIDE ION, ... | | Authors: | Birrane, G, Varma, A.K, Soni, A, Ladias, J.A.A. | | Deposit date: | 2006-11-07 | | Release date: | 2007-06-12 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the BARD1 BRCT domains.
Biochemistry, 46, 2007
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3C5R
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2R1Z
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3FA2
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7LYC
 | | Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A Lys13 and Lys15 in complex with BARD1 (residues 415-777) | | Descriptor: | BRCA1-associated RING domain protein 1, DNA (146-MER), DNA (147-MER), ... | | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G. | | Deposit date: | 2021-03-06 | | Release date: | 2021-06-16 | | Last modified: | 2021-09-01 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
Nature, 596, 2021
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7E8I
 | | Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin | | Descriptor: | BRCA1-associated RING domain protein 1, DNA (145-MER), Histone H2A, ... | | Authors: | Dai, Y, Dai, L, Zhou, Z. | | Deposit date: | 2021-03-01 | | Release date: | 2021-06-30 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin.
Mol.Cell, 81, 2021
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7LYB
 | | Cryo-EM structure of the human nucleosome core particle in complex with BRCA1-BARD1-UbcH5c | | Descriptor: | BRCA1-associated RING domain protein 1, DNA (146-MER), DNA (147-MER), ... | | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G. | | Deposit date: | 2021-03-06 | | Release date: | 2021-07-28 | | Last modified: | 2021-09-01 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
Nature, 596, 2021
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8GRQ
 | | Cryo-EM structure of BRCA1/BARD1 bound to H2AK127-UbcH5c-Ub nucleosome | | Descriptor: | BRCA1-associated RING domain protein 1, Breast cancer type 1 susceptibility protein, DNA (147-MER), ... | | Authors: | Ai, H.S, Zebin, T, Zhiheng, D, Jiakun, T, Liying, Z, Jia-Bin, L, Man, P, Liu, L. | | Deposit date: | 2022-09-02 | | Release date: | 2023-04-12 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.87 Å) | | Cite: | Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.
Chem, 2023
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7JZV
 | | Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome | | Descriptor: | BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ... | | Authors: | Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E. | | Deposit date: | 2020-09-02 | | Release date: | 2021-02-17 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Nat.Struct.Mol.Biol., 28, 2021
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1JM7
 | | Solution structure of the BRCA1/BARD1 RING-domain heterodimer | | Descriptor: | BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1, BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, ZINC ION | | Authors: | Brzovic, P.S, Rajagopal, P, Hoyt, D.W, King, M.-C, Klevit, R.E. | | Deposit date: | 2001-07-17 | | Release date: | 2001-10-03 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
Nat.Struct.Biol., 8, 2001
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