7UV8
| Rad6-Bre1 Complex | Descriptor: | E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2 | Authors: | Shukla, P.K, Chandrasekharan, M.B. | Deposit date: | 2022-04-29 | Release date: | 2023-01-11 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex. Nucleic Acids Res., 51, 2023
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7W75
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7W76
| Crystal structure of the K. lactis Bre1 RBD in complex with Rad6, crystal form II | Descriptor: | E3 ubiquitin-protein ligase BRE1, GLYCEROL, SULFATE ION, ... | Authors: | Shi, M, Zhao, J, Xiang, S. | Deposit date: | 2021-12-03 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural basis for the Rad6 activation by the Bre1 N-terminal domain. Elife, 12, 2023
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7WLH
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7UVC
| Rad6(P43L)-Bre1 Complex | Descriptor: | E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2 | Authors: | Shukla, P.K, Chandrasekharan, M.B. | Deposit date: | 2022-04-29 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex. Nucleic Acids Res., 51, 2023
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7V8F
| Crystal structure of UBE2L3 bound to HOIP RING1 domain. | Descriptor: | E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 L3, ZINC ION | Authors: | Liu, J, Wang, Y, Pan, L. | Deposit date: | 2021-08-22 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri. Proc.Natl.Acad.Sci.USA, 119, 2022
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3E95
| Crystal Structure of the Plasmodium Falciparum ubiquitin conjugating enzyme complex, PfUBC13-PfUev1a | Descriptor: | UNKNOWN ATOM OR ION, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2 | Authors: | Wernimont, A.K, Lam, A, Ali, A, Brokx, S, Lin, Y.H, Zhao, Y, Lew, J, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Schapira, M, Bochkarev, A, Wilkstrom, M, BOuntra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Qiu, W, Brand, V.B, Structural Genomics Consortium (SGC) | Deposit date: | 2008-08-21 | Release date: | 2008-09-30 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of the Plasmodium Falciparum ubiquitin conjugating enzyme complex, PfUBC13-PfUev1a TO BE PUBLISHED
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7YW1
| crystal structure of UBE2O | Descriptor: | (E3-independent) E2 ubiquitin-conjugating enzyme UBE2O | Authors: | Fu, Z, Zhu, W, Huang, H. | Deposit date: | 2022-08-20 | Release date: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.27 Å) | Cite: | crystal structure of UBE2O To Be Published
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6S98
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6S96
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3CEG
| Crystal structure of the UBC domain of baculoviral IAP repeat-containing protein 6 | Descriptor: | Baculoviral IAP repeat-containing protein 6 | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2008-02-29 | Release date: | 2008-04-01 | Last modified: | 2012-11-28 | Method: | X-RAY DIFFRACTION (2.008 Å) | Cite: | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
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6SYF
| Human Ubc9 with covalent isopeptide ligand | Descriptor: | ACE-ILE-LYS-GLN-GLU, ACE-LEU-ARG-LEU-ARG-GLY-CYS, SUMO-conjugating enzyme UBC9 | Authors: | Hofmann, R, Akimoto, G, Wucherpfennig, T.G, Zeymer, C, Bode, J.W. | Deposit date: | 2019-09-27 | Release date: | 2020-08-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins. Nat.Chem., 12, 2020
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4DS2
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6R75
| Crystal structure of human Ube2T E54R mutant | Descriptor: | Ubiquitin-conjugating enzyme E2 T | Authors: | Chaugule, V.K, Rennie, M.L, Walden, H, Arkinson, C, Kamarainen, O, Toth, R. | Deposit date: | 2019-03-28 | Release date: | 2019-10-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Allosteric mechanism for site-specific ubiquitination of FANCD2. Nat.Chem.Biol., 16, 2020
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5V0R
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4FH1
| S. cerevisiae Ubc13-N79A | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Ubiquitin-conjugating enzyme E2 13 | Authors: | Berndsen, C.E, Wolberger, C, Wiener, R. | Deposit date: | 2012-06-05 | Release date: | 2013-01-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | A conserved asparagine has a structural role in ubiquitin-conjugating enzymes. Nat.Chem.Biol., 9, 2013
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4ONL
| Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P | Descriptor: | Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 | Authors: | Hodge, C.D, Edwards, R.A, Glover, J.N.M. | Deposit date: | 2014-01-28 | Release date: | 2015-05-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. Acs Chem.Biol., 10, 2015
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4ONN
| Crystal structure of human Mms2/Ubc13 - BAY 11-7082 | Descriptor: | 3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ... | Authors: | Hodge, C.D, Edwards, R.A, Glover, J.N.M. | Deposit date: | 2014-01-28 | Release date: | 2015-05-06 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. Acs Chem.Biol., 10, 2015
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2GJD
| Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress | Descriptor: | Ubiquitin-conjugating enzyme E2-18 kDa | Authors: | van Waardenburg, R.C, Duda, D.M, Lancaster, C.S, Schulman, B.A, Bjornsti, M.A. | Deposit date: | 2006-03-30 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Distinct functional domains of ubc9 dictate cell survival and resistance to genotoxic stress. Mol.Cell.Biol., 26, 2006
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2KLY
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2H2Y
| Crystal structure of ubiquitin conjugating enzyme E2 from plasmodium falciparum | Descriptor: | Ubiquitin-conjugating enzyme | Authors: | Qiu, W, Dong, A, Zhao, Y, Lew, J, Kozieradski, I, Sundararajan, E, Melone, M, Wasney, G, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) | Deposit date: | 2006-05-19 | Release date: | 2006-06-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
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2HLW
| Solution Structure of the Human Ubiquitin-conjugating Enzyme Variant Uev1a | Descriptor: | Ubiquitin-conjugating enzyme E2 variant 1 | Authors: | Hau, D.D, Lewis, M.J, Saltibus, L.F, Pastushok, L, Xiao, W, Spyracopoulos, L. | Deposit date: | 2006-07-10 | Release date: | 2006-09-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure and interactions of the ubiquitin-conjugating enzyme variant human uev1a: implications for enzymatic synthesis of polyubiquitin chains(,). Biochemistry, 45, 2006
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2MT6
| Solution structure of the human ubiquitin conjugating enzyme Ube2w | Descriptor: | Ubiquitin-conjugating enzyme E2 W | Authors: | Vittal, V, Shi, L, Wenzel, D.M, Brzovic, P.S, Klevit, R.E. | Deposit date: | 2014-08-14 | Release date: | 2014-11-26 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Intrinsic disorder drives N-terminal ubiquitination by Ube2w. Nat.Chem.Biol., 11, 2015
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2ONU
| Plasmodium falciparum ubiquitin conjugating enzyme PF10_0330, putative homologue of human UBE2H | Descriptor: | TETRAETHYLENE GLYCOL, Ubiquitin-conjugating enzyme, putative | Authors: | Dong, A, Lew, J, Lin, L, Hassanali, A, Zhao, Y, Senisterra, G, Wasney, G, Vedadi, M, Kozieradzki, I, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Hui, R, Brokx, S.J, Structural Genomics Consortium (SGC) | Deposit date: | 2007-01-24 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Plasmodium falciparum ubiquitin conjugating enzyme PF10_0330, putative homologue of human UBE2H To be Published
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2OB4
| Human Ubiquitin-Conjugating Enzyme CDC34 | Descriptor: | Ubiquitin-conjugating enzyme E2-32 kDa complementing | Authors: | Neculai, D, Avvakumov, G.V, Xue, S, Walker, J.R, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Sicheri, F, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2006-12-18 | Release date: | 2006-12-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
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