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PDB: 188 results

4MM3
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BU of 4mm3 by Molmil
Crystal structure of SARS-CoV papain-like protease PLpro in complex with ubiquitin aldehyde
Descriptor: Papain-like proteinase, Ubiquitin, ZINC ION
Authors:Mesecar, A.D, Ratia, K.
Deposit date:2013-09-08
Release date:2014-07-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.752 Å)
Cite:Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease.
Plos Pathog., 10, 2014
2BX4
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BU of 2bx4 by Molmil
Crystal Structure of SARS Coronavirus Main Proteinase (P21212)
Descriptor: 3C-like proteinase nsp5
Authors:Verschueren, K.H.G, Mesters, J.R, Bigalke, J, Hilgenfeld, R.
Deposit date:2005-07-22
Release date:2005-09-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Ph-Dependent Conformational Flexibility of the Sars-Cov Main Proteinase (M(Pro)) Dimer: Molecular Dynamics Simulations and Multiple X-Ray Structure Analyses.
J.Mol.Biol., 354, 2005
2WCT
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BU of 2wct by Molmil
human SARS coronavirus unique domain (triclinic form)
Descriptor: NON-STRUCTURAL PROTEIN 3
Authors:Tan, J, Vonrhein, C, Smart, O.S, Bricogne, G, Bollati, M, Hansen, G, Mesters, J.R, Hilgenfeld, R.
Deposit date:2009-03-16
Release date:2009-05-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:The Sars-Unique Domain (Sud) of Sars Coronavirus Contains Two Macrodomains that Bind G-Quadruplexes.
Plos Pathog., 5, 2009
6JYT
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BU of 6jyt by Molmil
Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis
Descriptor: Helicase, ZINC ION
Authors:Yan, L, Jia, Z.
Deposit date:2019-04-28
Release date:2019-09-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis.
Nucleic Acids Res., 47, 2019
2RHB
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BU of 2rhb by Molmil
Crystal structure of Nsp15-H234A mutant- Hexamer in asymmetric unit
Descriptor: Uridylate-specific endoribonuclease
Authors:Palaninathan, S, Bhardwaj, K, Alcantara, J.M.O, Guarino, L, Yi, L.L, Kao, C.C, Sacchettini, J.
Deposit date:2007-10-08
Release date:2007-11-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15.
J.Biol.Chem., 283, 2008
1Z1J
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BU of 1z1j by Molmil
Crystal structure of SARS 3CLpro C145A mutant
Descriptor: 3C-like proteinase
Authors:Hsu, M.F.
Deposit date:2005-03-04
Release date:2005-11-22
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Understanding the maturation process and inhibitor design of SARS-CoV 3CLpro from the crystal structure of C145A in a product-bound form
J.Biol.Chem., 280, 2005
1Z1I
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BU of 1z1i by Molmil
Crystal structure of native SARS CLpro
Descriptor: 3C-like proteinase
Authors:Liang, P.H, Wang, A.H.
Deposit date:2005-03-04
Release date:2005-11-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Understanding the maturation process and inhibitor design of SARS-CoV 3CLpro from the crystal structure of C145A in a product-bound form
J.Biol.Chem., 280, 2005
1UW7
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BU of 1uw7 by Molmil
Nsp9 protein from SARS-coronavirus.
Descriptor: NSP9
Authors:Sutton, G, Fry, E, Carter, L, Sainsbury, S, Walter, T, Nettleship, J, Berrow, N, Owens, R, Gilbert, R, Davidson, A, Siddell, S, Poon, L.L.M, Diprose, J, Alderton, D, Walsh, M, Grimes, J.M, Stuart, D.I.
Deposit date:2004-01-30
Release date:2004-02-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Nsp9 Replicase Protein of Sars-Coronavirus, Structure and Functional Insights
Structure, 12, 2004
5E6J
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BU of 5e6j by Molmil
Structure of SARS PLpro bound to a Lys48-linked di-ubiquitin activity based probe
Descriptor: ACETATE ION, NICKEL (II) ION, Polyubiquitin-B, ...
Authors:Lima, C.D, Bekes, M.
Deposit date:2015-10-09
Release date:2016-05-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease.
Mol. Cell, 62, 2016
3M3T
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BU of 3m3t by Molmil
SARS-CoV main protease monomeric Arg298Ala mutant with N-terminal additional residues (Gly-Ser)
Descriptor: 3C-like proteinase
Authors:Shi, J.H, Song, J.X.
Deposit date:2010-03-10
Release date:2011-03-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:SARS-CoV main protease with N-terminal extension regulated by mutation on C-terminal domain
To be Published
3F9H
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BU of 3f9h by Molmil
Crystal Structure of the F140A mutant of SARS-Coronovirus 3C-like Protease at pH 7.6
Descriptor: 3C-like proteinase
Authors:Hu, T, Li, L, Jiang, H, Shen, X.
Deposit date:2008-11-13
Release date:2009-09-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure.
Virology, 388, 2009
2OZK
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BU of 2ozk by Molmil
Structure of an N-Terminal Truncated Form of Nendou (NSP15) From SARS-CORONAVIRUS
Descriptor: Uridylate-specific endoribonuclease
Authors:Saikatendu, K, Joseph, J, Subramanian, V, Neuman, B, Buchmeier, M, Stevens, R.C, Kuhn, P.
Deposit date:2007-02-26
Release date:2007-05-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a monomeric form of severe acute respiratory syndrome coronavirus endonuclease nsp15 suggests a role for hexamerization as an allosteric switch.
J.Virol., 81, 2007
3SNA
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BU of 3sna by Molmil
Crystal structure of SARS coronavirus main protease complexed with Ac-NSFSQ-H (soaking)
Descriptor: 3C-like proteinase, Peptide aldehyde inhibitor Ac-NSFSQ-H
Authors:Zhu, L, Hilgenfeld, R.
Deposit date:2011-06-29
Release date:2011-09-07
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease.
Antiviral Res., 92, 2011
6NUR
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BU of 6nur by Molmil
SARS-Coronavirus NSP12 bound to NSP7 and NSP8 co-factors
Descriptor: NSP12, NSP7, NSP8, ...
Authors:Kirchdoerfer, R.N, Ward, A.B.
Deposit date:2019-02-01
Release date:2019-05-29
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.
Nat Commun, 10, 2019
3IWM
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BU of 3iwm by Molmil
The octameric SARS-CoV main protease
Descriptor: 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Zhong, N, Zhang, S, Xue, F, Lou, Z, Rao, Z, Xia, B.
Deposit date:2009-09-02
Release date:2010-07-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Three-dimensional domain swapping as a mechanism to lock the active conformation in a super-active octamer of SARS-CoV main protease
Protein Cell, 1, 2010
5C8T
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BU of 5c8t by Molmil
Crystal structure of the SARS coronavirus nsp14-nsp10 complex with functional ligand SAM
Descriptor: Guanine-N7 methyltransferase, MAGNESIUM ION, Non-structural protein 10, ...
Authors:Ma, Y.Y, Wu, L.J, Zhang, R.G, Rao, Z.H.
Deposit date:2015-06-26
Release date:2015-07-15
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex
Proc.Natl.Acad.Sci.USA, 112, 2015
5C8S
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BU of 5c8s by Molmil
Crystal structure of the SARS coronavirus nsp14-nsp10 complex with functional ligands SAH and GpppA
Descriptor: GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, Guanine-N7 methyltransferase, MAGNESIUM ION, ...
Authors:Ma, Y.Y, Wu, L.J, Zhang, R.G, Rao, Z.H.
Deposit date:2015-06-26
Release date:2015-07-15
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (3.326 Å)
Cite:Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex
Proc.Natl.Acad.Sci.USA, 112, 2015
5NFY
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BU of 5nfy by Molmil
SARS-CoV nsp10/nsp14 dynamic complex
Descriptor: DI(HYDROXYETHYL)ETHER, Polyprotein 1ab, ZINC ION
Authors:Ferron, F, Gluais, L, Vonrhein, C, Bricogne, G, Canard, B, Imbert, I.
Deposit date:2017-03-16
Release date:2018-01-10
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.382 Å)
Cite:Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5C8U
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BU of 5c8u by Molmil
Crystal structure of the SARS coronavirus nsp14-nsp10 complex
Descriptor: Guanine-N7 methyltransferase, MAGNESIUM ION, Non-structural protein 10, ...
Authors:Ma, Y.Y, Wu, L.J, Zhang, R.G, Rao, Z.H.
Deposit date:2015-06-26
Release date:2015-07-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.401 Å)
Cite:Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex
Proc.Natl.Acad.Sci.USA, 112, 2015
6YXJ
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BU of 6yxj by Molmil
Crystal structure of SARS-CoV macrodomain II in complex with human Paip1
Descriptor: Non-structural protein 3, Polyadenylate-binding protein-interacting protein 1
Authors:Lei, J, Hilgenfeld, R.
Deposit date:2020-05-02
Release date:2021-03-17
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The SARS-unique domain (SUD) of SARS-CoV and SARS-CoV-2 interacts with human Paip1 to enhance viral RNA translation.
Embo J., 40, 2021
6NUS
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BU of 6nus by Molmil
SARS-Coronavirus NSP12 bound to NSP8 co-factor
Descriptor: NSP12, NSP8, ZINC ION
Authors:Kirchdoerfer, R.N, Ward, A.B.
Deposit date:2019-02-01
Release date:2019-05-29
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.
Nat Commun, 10, 2019
7OPL
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BU of 7opl by Molmil
CryoEM structure of DNA Polymerase alpha - primase bound to SARS CoV nsp1
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ...
Authors:Kilkenny, M.L, Pellegrini, L.
Deposit date:2021-06-01
Release date:2021-11-10
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.12 Å)
Cite:Structural basis for the interaction of SARS-CoV-2 virulence factor nsp1 with DNA polymerase alpha-primase.
Protein Sci., 31, 2022
2JZF
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BU of 2jzf by Molmil
NMR Conformer closest to the mean coordinates of the domain 513-651 of the SARS-CoV nonstructural protein nsp3
Descriptor: Replicase polyprotein 1ab
Authors:Chatterjee, A, Johnson, M.A, Serrano, P, Pedrini, B, Joseph, J, Saikatendu, K, Neuman, B, Stevens, R.C, Wilson, I.A, Buchmeier, M.J, Kuhn, P, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2008-01-04
Release date:2008-02-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structure shows that the severe acute respiratory syndrome coronavirus-unique domain contains a macrodomain fold.
J.Virol., 83, 2009
2RNK
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BU of 2rnk by Molmil
NMR structure of the domain 513-651 of the SARS-CoV nonstructural protein nsp3
Descriptor: Replicase polyprotein 1ab
Authors:Chatterjee, A, Johnson, M.A, Serrano, P, Pedrini, B, Joseph, J, Saikatendu, K, Neuman, B.W, Wilson, I.A, Stevens, R.C, Buchmeier, M.J, Kuhn, P, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2008-01-11
Release date:2008-02-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structure shows that the severe acute respiratory syndrome coronavirus-unique domain contains a macrodomain fold.
J.Virol., 83, 2009
2GRI
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BU of 2gri by Molmil
NMR Structure of the SARS-CoV non-structural protein nsp3a
Descriptor: NSP3
Authors:Serrano, P, Almeida, M.S, Johnson, M.A, Herrmann, T, Saikatendu, K.S, Joseph, J, Subramanian, V, Neuman, B.W, Buchmeier, M.J, Stevens, R.C, Kuhn, P, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
Deposit date:2006-04-24
Release date:2006-12-19
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus.
J.Virol., 81, 2007

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数据于2024-07-10公开中

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