7ZI4
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![BU of 7zi4 by Molmil](/molmil-images/mine/7zi4) | Cryo-EM structure of the human INO80 complex bound to a WT nucleosome | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Vance, N.R, Ayala, R, Willhoft, O, Tvardovskiy, A, McCormack, E.A, Bartke, T, Zhang, X, Wigley, D.B. | Deposit date: | 2022-04-07 | Release date: | 2023-04-19 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the human INO80 complex bound to a WT nucleosome To Be Published
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3WAA
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![BU of 3waa by Molmil](/molmil-images/mine/3waa) | The nucleosome containing human H2A.Z.2 | Descriptor: | DNA (146-MER), Histone H2A.V, Histone H2B type 1-J, ... | Authors: | Horikoshi, N, Sato, K, Shimada, K, Arimura, Y, Osakabe, A, Tachiwana, H, Iwasaki, W, Kagawa, W, Harata, M, Kimura, H, Kurumizaka, H. | Deposit date: | 2013-04-30 | Release date: | 2013-12-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2 Acta Crystallogr.,Sect.D, 69, 2013
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3X1U
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![BU of 3x1u by Molmil](/molmil-images/mine/3x1u) | |
8X7K
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![BU of 8x7k by Molmil](/molmil-images/mine/8x7k) | Cryo-EM structures of RNF168/UbcH5c-Ub in complex with H2AK13Ub nucleosomes determined by activity-based chemical trapping strategy (adjacent H2AK13/15 dual-monoubiquitination) | Descriptor: | DNA (143-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Ai, H.S, Tong, Z.B, Deng, Z.H, Pan, M, Liu, L. | Deposit date: | 2023-11-24 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168 Biorxiv, 2024
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8X7I
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![BU of 8x7i by Molmil](/molmil-images/mine/8x7i) | Cryo-EM structures of RNF168/UbcH5c-Ub in complex with H2AK13Ub nucleosomes determined by intein-based E2-Ub-NCP conjugation strategy | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Ai, H.S, Tong, Z.B, Deng, Z.H, Pan, M, Liu, L. | Deposit date: | 2023-11-24 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168 Biorxiv, 2024
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7LYB
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![BU of 7lyb by Molmil](/molmil-images/mine/7lyb) | Cryo-EM structure of the human nucleosome core particle in complex with BRCA1-BARD1-UbcH5c | Descriptor: | BRCA1-associated RING domain protein 1, DNA (146-MER), DNA (147-MER), ... | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G. | Deposit date: | 2021-03-06 | Release date: | 2021-07-28 | Last modified: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. Nature, 596, 2021
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8OOS
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![BU of 8oos by Molmil](/molmil-images/mine/8oos) | CryoEM Structure INO80core Hexasome complex ATPase-hexasome refinement state 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chromatin-remodeling ATPase Ino80, DNA Strand 2, ... | Authors: | Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S. | Deposit date: | 2023-04-05 | Release date: | 2023-07-26 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling. Science, 381, 2023
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8SMW
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![BU of 8smw by Molmil](/molmil-images/mine/8smw) | Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 1) | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | Deposit date: | 2023-04-26 | Release date: | 2024-01-17 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8SN1
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![BU of 8sn1 by Molmil](/molmil-images/mine/8sn1) | Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 6) | Descriptor: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | Deposit date: | 2023-04-26 | Release date: | 2024-01-17 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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7JO9
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![BU of 7jo9 by Molmil](/molmil-images/mine/7jo9) | 1:1 cGAS-nucleosome complex | Descriptor: | Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... | Authors: | Boyer, J.A, Spangler, C.J, Strauss, J.D, Cesmat, A.P, Liu, P, McGinty, R.K, Zhang, Q. | Deposit date: | 2020-08-06 | Release date: | 2020-09-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of nucleosome-dependent cGAS inhibition. Science, 370, 2020
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7JOA
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![BU of 7joa by Molmil](/molmil-images/mine/7joa) | 2:1 cGAS-nucleosome complex | Descriptor: | Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... | Authors: | Boyer, J.A, Spangler, C.J, Strauss, J.D, Cesmat, A.P, Liu, P, McGinty, R.K, Zhang, Q. | Deposit date: | 2020-08-06 | Release date: | 2020-09-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of nucleosome-dependent cGAS inhibition. Science, 370, 2020
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8OTS
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![BU of 8ots by Molmil](/molmil-images/mine/8ots) | OCT4 and MYC-MAX co-bound to a nucleosome | Descriptor: | DNA (127-MER), Green fluorescent protein,POU domain, class 5, ... | Authors: | Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N. | Deposit date: | 2023-04-21 | Release date: | 2023-05-24 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cooperation between bHLH transcription factors and histones for DNA access. Nature, 619, 2023
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8OTT
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![BU of 8ott by Molmil](/molmil-images/mine/8ott) | MYC-MAX bound to a nucleosome at SHL+5.8 | Descriptor: | DNA (144-MER), Histone H2A type 1-B/E, Histone H2A type 1-K, ... | Authors: | Stoos, L, Michael, A.K, Kempf, G, Kater, L, Cavadini, S, Thoma, N. | Deposit date: | 2023-04-21 | Release date: | 2023-05-24 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cooperation between bHLH transcription factors and histones for DNA access. Nature, 619, 2023
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5B40
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![BU of 5b40 by Molmil](/molmil-images/mine/5b40) | The nucleosome structure containing H2B-K120 and H4-K31 monoubiquitinations | Descriptor: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Machida, S, Sekine, S, Nishiyama, Y, Horikoshi, N, Kurumizaka, H. | Deposit date: | 2016-03-22 | Release date: | 2016-06-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | Monoubiquitination of histones H2B and H4 changes the nucleosome stability without affecting the nucleosome structure To Be Published
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8JBX
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7YQK
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![BU of 7yqk by Molmil](/molmil-images/mine/7yqk) | cryo-EM structure of gammaH2AXK15ub-H4K20me2 nucleosome bound to 53BP1 | Descriptor: | DNA (145-MER), Histone H2AX, Histone H2B, ... | Authors: | Ai, H.S, GuoChao, C, Qingyue, G, Ze-Bin, T, Zhiheng, D, Xin, L, Fan, Y, Ziyu, X, Jia-Bin, L, Changlin, T, Liu, L. | Deposit date: | 2022-08-07 | Release date: | 2022-08-17 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes. J.Am.Chem.Soc., 144, 2022
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8X7J
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![BU of 8x7j by Molmil](/molmil-images/mine/8x7j) | Cryo-EM structures of RNF168/UbcH5c-Ub/nucleosomes complex determined by activity-based chemical trapping strategy | Descriptor: | DNA (144-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | Authors: | Ai, H.S, Tong, Z.B, Deng, Z.H, Pan, M, Liu, L. | Deposit date: | 2023-11-24 | Release date: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168 Biorxiv, 2024
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7XX6
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![BU of 7xx6 by Molmil](/molmil-images/mine/7xx6) | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment) | Descriptor: | CALCIUM ION, DNA (169-MER), Histone H1.0, ... | Authors: | Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. | Deposit date: | 2022-05-28 | Release date: | 2023-05-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment) To Be Published
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6O1D
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![BU of 6o1d by Molmil](/molmil-images/mine/6o1d) | |
6LA8
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![BU of 6la8 by Molmil](/molmil-images/mine/6la8) | 349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 | Descriptor: | CALCIUM ION, DNA (349-MER), Histone H1.0, ... | Authors: | Adhireksan, Z, Lee, P.L, Sharma, D, Davey, C.A. | Deposit date: | 2019-11-12 | Release date: | 2020-10-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Near-atomic resolution structures of interdigitated nucleosome fibres. Nat Commun, 11, 2020
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8OFF
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![BU of 8off by Molmil](/molmil-images/mine/8off) | Structure of BARD1 ARD-BRCTs in complex with H2AKc15ub nucleosomes (Map1) | Descriptor: | BRCA1 associated RING domain 1, DNA (142-MER), Histone H2A type 1, ... | Authors: | Foglizzo, M, Burdett, H, Wilson, M.D, Zeqiraj, E. | Deposit date: | 2023-03-15 | Release date: | 2023-10-11 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | BRCA1-BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes. Nucleic Acids Res., 51, 2023
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7U50
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![BU of 7u50 by Molmil](/molmil-images/mine/7u50) | |
7U52
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![BU of 7u52 by Molmil](/molmil-images/mine/7u52) | |
7XSZ
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![BU of 7xsz by Molmil](/molmil-images/mine/7xsz) | RNA polymerase II elongation complex transcribing a nucleosome (EC115) | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | Deposit date: | 2022-05-15 | Release date: | 2022-09-07 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Science, 377, 2022
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6YOV
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![BU of 6yov by Molmil](/molmil-images/mine/6yov) | OCT4-SOX2-bound nucleosome - SHL+6 | Descriptor: | DNA (142-MER), Green fluorescent protein,POU domain, class 5, ... | Authors: | Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. | Deposit date: | 2020-04-15 | Release date: | 2020-05-06 | Last modified: | 2020-07-08 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science, 368, 2020
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