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PDB: 238582 results

1RWO
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Crystal structure of human caspase-1 in complex with 4-oxo-3-{6-[4-(quinoxalin-2-ylamino)-benzoylamino]-2-thiophen-2-yl-hexanoylamino}-pentanoic acid
Descriptor: 4-OXO-3-{6-[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-PENTANOIC ACID, Interleukin-1 beta convertase
Authors:Romanowski, M.J, Waal, N.D, Fahr, B.T, O'Brien, T.
Deposit date:2003-12-16
Release date:2004-12-28
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of caspase-1 inhibitors derived from Tethering.
Acta Crystallogr.,Sect.F, 61, 2005
1RWP
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Crystal structure of human caspase-1 in complex with 3-{6-[(8-hydroxy-quinoline-2-carbonyl)-amino]-2-thiophen-2-yl-hexanoylamino}-4-oxo-butyric acid
Descriptor: 3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID, Interleukin-1 beta convertase
Authors:Romanowski, M.J, Fahr, B.T, O'Brien, T.
Deposit date:2003-12-16
Release date:2004-12-28
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural analysis of caspase-1 inhibitors derived from Tethering.
Acta Crystallogr.,Sect.F, 61, 2005
1RWQ
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Human Dipeptidyl peptidase IV in complex with 5-aminomethyl-6-(2,4-dichloro-phenyl)-2-(3,5-dimethoxy-phenyl)-pyrimidin-4-ylamine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-(AMINOMETHYL)-6-(2,4-DICHLOROPHENYL)-2-(3,5-DIMETHOXYPHENYL)PYRIMIDIN-4-AMINE, Dipeptidyl peptidase IV
Authors:Hennig, M, Thoma, R, Stihle, M.
Deposit date:2003-12-17
Release date:2004-12-17
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Aminomethylpyrimidines as novel DPP-IV inhibitors: a 10(5)-fold activity increase by optimization of aromatic substituents
Bioorg.Med.Chem.Lett., 14, 2004
1RWR
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BU of 1rwr by Molmil
Crystal structure of filamentous hemagglutinin secretion domain
Descriptor: Filamentous hemagglutinin
Authors:Clantin, B, Villeret, V.
Deposit date:2003-12-17
Release date:2004-04-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:The crystal structure of filamentous hemagglutinin secretion domain and its implications for the two-partner secretion pathway
Proc.Natl.Acad.Sci.USA, 101, 2004
1RWS
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BU of 1rws by Molmil
Backbone Solution Structure of mixed alpha/beta protein PF1061
Descriptor: hypothetical protein PF1061
Authors:Prestegard, J.H, Mayer, K.L, Valafar, H.
Deposit date:2003-12-17
Release date:2003-12-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Backbone solution structures of proteins using residual dipolar couplings: application to a novel structural genomics target.
J.STRUCT.FUNCT.GENOM., 5, 2004
1RWT
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BU of 1rwt by Molmil
Crystal Structure of Spinach Major Light-harvesting complex at 2.72 Angstrom Resolution
Descriptor: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
Authors:Liu, Z, Yan, H, Wang, K, Kuang, T, Zhang, J, Gui, L, An, X, Chang, W.
Deposit date:2003-12-17
Release date:2004-03-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Crystal structure of spinach major light-harvesting complex at 2.72 A resolution
Nature, 428, 2004
1RWU
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Solution structure of conserved protein YbeD from E. coli
Descriptor: Hypothetical UPF0250 protein ybeD
Authors:Kozlov, G, Arrowsmith, C.H, Gehring, K, Northeast Structural Genomics Consortium (NESG)
Deposit date:2003-12-17
Release date:2004-12-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural similarity of YbeD protein from Escherichia coli to allosteric regulatory domains
J.Bacteriol., 186, 2004
1RWV
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BU of 1rwv by Molmil
Crystal structure of human caspase-1 in complex with 5-[5-(1-carboxymethyl-2-oxo-propylcarbamoyl)-5-phenyl-pentylsulfamoyl]-2-hydroxy-benzoic acid
Descriptor: 5-[5-(1-CARBOXYMETHYL-2-OXO-PROPYLCARBAMOYL)-5-PHENYL-PENTYLSULFAMOYL]-2-HYDROXY-BENZOIC ACID, Interleukin-1 beta convertase
Authors:Romanowski, M.J, Burdett, M.T, Fahr, B.T, O'Brien, T.
Deposit date:2003-12-17
Release date:2004-12-28
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel Caspase-1 Inhibitors Discovered Using Tethering(SM) with Extenders
TO BE PUBLISHED
1RWW
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Crystal structure of human caspase-1 in complex with 4-oxo-3-[(6-{[4-(quinoxalin-2-ylamino)-benzoylamino]-methyl}-pyridine-3-carbonyl)-amino]-butyric acid
Descriptor: 4-OXO-3-[(6-{[4-(QUINOXALIN-2-YLAMINO)-BENZOYLAMINO]-METHYL}-PYRIDINE-3-CARBONYL)-AMINO]-BUTYRIC ACID, Interleukin-1 beta convertase
Authors:Romanowski, M.J, Fahr, B.T, O'Brien, T.
Deposit date:2003-12-17
Release date:2004-12-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Tethering identifies fragment that yields potent inhibitors of human caspase-1.
Bioorg.Med.Chem.Lett., 16, 2006
1RWX
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Crystal structure of human caspase-1 in complex with 4-oxo-3-{6-[4-(quinoxalin-2-yloxy)-benzoylamino]-2-thiophen-2-yl-hexanoylamino}-butyric acid
Descriptor: 4-OXO-3-{6-[4-(QUINOXALIN-2-YLOXY)-BENZOYLAMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-BUTYRIC ACID, Interleukin-1 beta convertase
Authors:Romanowski, M.J, Fahr, B.T, O'Brien, T.
Deposit date:2003-12-17
Release date:2004-12-28
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Tethering identifies fragment that yields potent inhibitors of human caspase-1.
Bioorg.Med.Chem.Lett., 16, 2006
1RWY
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BU of 1rwy by Molmil
CRYSTAL STRUCTURE OF RAT ALPHA-PARVALBUMIN AT 1.05 RESOLUTION
Descriptor: ACETIC ACID, AMMONIUM ION, CALCIUM ION, ...
Authors:Bottoms, C.A, Schuermann, J.P, Agah, S, Henzl, M.T, Tanner, J.J.
Deposit date:2003-12-17
Release date:2004-05-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Crystal Structure of Rat Alpha-Parvalbumin at 1.05 Resolution
Protein Sci., 13, 2004
1RWZ
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Crystal Structure of Proliferating Cell Nuclear Antigen (PCNA) from A. fulgidus
Descriptor: DNA polymerase sliding clamp
Authors:Chapados, B.R, Hosfield, D.J, Han, S, Qiu, J, Yelent, B, Shen, B, Tainer, J.A.
Deposit date:2003-12-17
Release date:2004-01-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell(Cambridge,Mass.), 116, 2004
1RX0
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Crystal structure of isobutyryl-CoA dehydrogenase complexed with substrate/ligand.
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, Acyl-CoA dehydrogenase family member 8, ...
Authors:Battaile, K.P, Nguyen, T.V, Vockley, J, Kim, J.J.
Deposit date:2003-12-18
Release date:2004-04-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structures of Isobutyryl-CoA Dehydrogenase and Enzyme-Product Complex: COMPARISON WITH ISOVALERYL- AND SHORT-CHAIN ACYL-COA DEHYDROGENASES.
J.Biol.Chem., 279, 2004
1RX1
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DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM)
Descriptor: CALCIUM ION, DIHYDROFOLATE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sawaya, M.R.
Deposit date:1996-09-19
Release date:1997-01-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RX2
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BU of 1rx2 by Molmil
DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH WITH FOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
Descriptor: BETA-MERCAPTOETHANOL, DIHYDROFOLATE REDUCTASE, FOLIC ACID, ...
Authors:Sawaya, M.R.
Deposit date:1996-09-19
Release date:1997-01-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RX3
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BU of 1rx3 by Molmil
DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM)
Descriptor: BETA-MERCAPTOETHANOL, DIHYDROFOLATE REDUCTASE, MANGANESE (II) ION, ...
Authors:Sawaya, M.R.
Deposit date:1996-09-19
Release date:1997-01-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RX4
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BU of 1rx4 by Molmil
DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE AND 2'-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE
Descriptor: 5,10-DIDEAZATETRAHYDROFOLIC ACID, BETA-MERCAPTOETHANOL, DIHYDROFOLATE REDUCTASE, ...
Authors:Sawaya, M.R.
Deposit date:1996-09-19
Release date:1997-01-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RX5
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BU of 1rx5 by Molmil
DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE
Descriptor: 5,10-DIDEAZATETRAHYDROFOLIC ACID, DIHYDROFOLATE REDUCTASE
Authors:Sawaya, M.R.
Deposit date:1996-09-19
Release date:1997-01-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RX6
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BU of 1rx6 by Molmil
DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM)
Descriptor: 5,10-DIDEAZATETRAHYDROFOLIC ACID, BETA-MERCAPTOETHANOL, DIHYDROFOLATE REDUCTASE, ...
Authors:Sawaya, M.R.
Deposit date:1996-09-19
Release date:1997-01-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RX7
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BU of 1rx7 by Molmil
STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE
Descriptor: DIHYDROFOLATE REDUCTASE, FOLIC ACID
Authors:Sawaya, M.R.
Deposit date:1996-10-25
Release date:1997-03-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RX8
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BU of 1rx8 by Molmil
DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 2'-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE
Descriptor: BETA-MERCAPTOETHANOL, DIHYDROFOLATE REDUCTASE, FOLIC ACID, ...
Authors:Sawaya, M.R.
Deposit date:1996-10-25
Release date:1997-03-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RX9
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BU of 1rx9 by Molmil
DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
Descriptor: BETA-MERCAPTOETHANOL, CALCIUM ION, DIHYDROFOLATE REDUCTASE, ...
Authors:Sawaya, M.R, Kraut, J.
Deposit date:1996-10-25
Release date:1997-04-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
1RXA
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BU of 1rxa by Molmil
CRYSTAL STRUCTURE OF R(CCCCGGGG) IN TWO DISTINCT LATTICES
Descriptor: RNA (5'-R(*CP*CP*CP*CP*GP*GP*GP*G)-3')
Authors:Portmann, S, Usman, N, Egli, M.
Deposit date:1995-05-05
Release date:1996-10-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of r(CCCCGGGG) in two distinct lattices.
Biochemistry, 34, 1995
1RXB
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BU of 1rxb by Molmil
CRYSTAL STRUCTURE OF R(CCCCGGGG) IN TWO DISTINCT LATTICES
Descriptor: RNA (5'-R(*CP*CP*CP*CP*GP*GP*GP*G)-3')
Authors:Portmann, S, Usman, N, Egli, M.
Deposit date:1995-05-05
Release date:1996-08-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of r(CCCCGGGG) in two distinct lattices.
Biochemistry, 34, 1995
1RXC
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BU of 1rxc by Molmil
E. COLI uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex
Descriptor: 1-O-phosphono-alpha-D-ribofuranose, 5-FLUOROURACIL, 5-FLUOROURIDINE, ...
Authors:Caradoc-Davies, T.T, Cutfield, S.M, Lamont, I.L, Cutfield, J.F.
Deposit date:2003-12-18
Release date:2004-04-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structures of escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium
J.Mol.Biol., 337, 2004

238582

数据于2025-07-09公开中

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