1RXC

E. COLI uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex

Summary for 1RXC

Entry DOI	10.2210/pdb1rxc/pdb
Related	1LGG 1RXS 1RXU 1RXY
Descriptor	Uridine phosphorylase, POTASSIUM ION, 1-O-phosphono-alpha-D-ribofuranose, ... (7 entities in total)
Functional Keywords	pentosyltransferase, uridine phosphorylase, 5-fluorouracil, induced fit, specificity, potassium, transferase
Biological source	Escherichia coli
Total number of polymer chains	12
Total formula weight	329702.81
Authors	Caradoc-Davies, T.T.,Cutfield, S.M.,Lamont, I.L.,Cutfield, J.F. (deposition date: 2003-12-18, release date: 2004-04-13, Last modification date: 2024-03-13)
Primary citation	Caradoc-Davies, T.T.,Cutfield, S.M.,Lamont, I.L.,Cutfield, J.F. Crystal structures of escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium J.Mol.Biol., 337:337-354, 2004 Cited by PubMed: 15003451 DOI: 10.1016/j.jmb.2004.01.039 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation