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5FD9
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BU of 5fd9 by Molmil
X-ray Crystal Structure of ESCRT-III Snf7 core domain (conformation B)
Descriptor: Vacuolar-sorting protein SNF7
Authors:Tang, S, Henne, W.M, Borbat, P.P, Buchkovich, N.J, Freed, J.H, Mao, Y, Fromme, J.C, Emr, S.D.
Deposit date:2015-12-15
Release date:2015-12-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments.
Elife, 4, 2015
6ZH3
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BU of 6zh3 by Molmil
Cryo-EM structure of ESCRT-III helical Vps24 filaments
Descriptor: Vacuolar protein-sorting-associated protein 24
Authors:Huber, S.T, Mostafavi, S, Mortensen, S.A, Sachse, C.
Deposit date:2020-06-20
Release date:2020-08-26
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure and assembly of ESCRT-III helical Vps24 filaments.
Sci Adv, 6, 2020
2GD5
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BU of 2gd5 by Molmil
Structural basis for budding by the ESCRTIII factor CHMP3
Descriptor: Charged multivesicular body protein 3
Authors:Muziol, T.M, Pineda-Molina, E, Ravelli, R.B, Zamborlini, A, Usami, Y, Gottlinger, H, Weissenhorn, W.
Deposit date:2006-03-15
Release date:2006-06-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Budding by the ESCRT-III Factor CHMP3.
Dev.Cell, 10, 2006
5J45
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BU of 5j45 by Molmil
Crystal structure of Shrub, fly ortholog of SNF7/CHMP4B
Descriptor: GH13992p
Authors:McMillan, B.J, Blacklow, S.C.
Deposit date:2016-03-31
Release date:2016-07-20
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (2.758 Å)
Cite:Electrostatic Interactions between Elongated Monomers Drive Filamentation of Drosophila Shrub, a Metazoan ESCRT-III Protein.
Cell Rep, 16, 2016
5FD7
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BU of 5fd7 by Molmil
X-ray Crystal Structure of ESCRT-III Snf7 core domain (conformation A)
Descriptor: Vacuolar-sorting protein SNF7
Authors:Tang, S, Henne, W.M, Borbat, P.P, Buchkovich, N.J, Freed, J.H, Mao, Y, Fromme, J.C, Emr, S.D.
Deposit date:2015-12-15
Release date:2015-12-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments.
Elife, 4, 2015
8WB7
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BU of 8wb7 by Molmil
CryoEM structure of Snf7 N-terminal domain in the inner coils of spiral
Descriptor: SNF7 isoform 1
Authors:Liu, M.D, Shen, Q.T.
Deposit date:2023-09-08
Release date:2024-05-29
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Three-dimensional architecture of ESCRT-III flat spirals on the membrane.
Proc.Natl.Acad.Sci.USA, 121, 2024
8WB6
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BU of 8wb6 by Molmil
Cryo-EM structure of Snf7 N-terminal domain in outer coils of spiral polymers
Descriptor: SNF7 isoform 1
Authors:Liu, M.D, Shen, Q.T.
Deposit date:2023-09-08
Release date:2024-05-29
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Three-dimensional architecture of ESCRT-III flat spirals on the membrane.
Proc.Natl.Acad.Sci.USA, 121, 2024
7ZCH
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BU of 7zch by Molmil
CHMP2A-CHMP3 heterodimer (410 Angstrom diameter)
Descriptor: Charged multivesicular body protein 2a, Charged multivesicular body protein 3
Authors:Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W.
Deposit date:2022-03-28
Release date:2023-01-18
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
7ZCG
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BU of 7zcg by Molmil
CHMP2A-CHMP3 heterodimer (430 Angstrom diameter)
Descriptor: Charged multivesicular body protein 2a, Charged multivesicular body protein 3
Authors:Azad, K, Desfosses, A, Effantin, G, Schoehn, G, Weissenhorn, W.
Deposit date:2022-03-28
Release date:2023-01-18
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage.
Nat.Struct.Mol.Biol., 30, 2023
3FRT
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BU of 3frt by Molmil
The structure of human CHMP3 (residues 8 - 222).
Descriptor: Charged multivesicular body protein 3
Authors:Schubert, H.L, McCullough, J, Hill, C.P, Sundquist, W.I.
Deposit date:2009-01-08
Release date:2009-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structural basis for ESCRT-III protein autoinhibition.
Nat.Struct.Mol.Biol., 16, 2009
3FRV
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BU of 3frv by Molmil
Structure of Human CHMP3 (residues 1-150)
Descriptor: Charged multivesicular body protein 3
Authors:Hill, C.P, Schubert, H.L, McCullough, J, Sundquist, W.I.
Deposit date:2009-01-08
Release date:2009-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural basis for ESCRT-III protein autoinhibition.
Nat.Struct.Mol.Biol., 16, 2009
5T8N
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BU of 5t8n by Molmil
Crystal structure of Snf7 under 200 MPa
Descriptor: Vacuolar-sorting protein SNF7
Authors:Huang, Q, Szebenyi, D.
Deposit date:2016-09-07
Release date:2017-08-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Crystal structure of Snf7 under 200 MPa
To Be Published
5T8L
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BU of 5t8l by Molmil
Crystal structure of Snf7 under 350 MPa
Descriptor: Vacuolar-sorting protein SNF7
Authors:Huang, Q, Szebenyi, D.
Deposit date:2016-09-07
Release date:2017-08-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Snf7 under 350 MPa
To Be Published
4ABM
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BU of 4abm by Molmil
Crystal Structure of CHMP4B hairpin
Descriptor: CHARGED MULTIVESICULAR BODY PROTEIN 4B
Authors:Martinelli, N, Hartlieb, B, Usami, Y, Sabin, C, Dordor, A, Ribeiro, E.A, Gottlinger, H, Weissenhorn, W.
Deposit date:2011-12-08
Release date:2012-05-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cc2D1A is a Regulator of Escrt-III Chmp4B.
J.Mol.Biol., 419, 2012
6TZ9
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BU of 6tz9 by Molmil
CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B only
Descriptor: Charged multivesicular body protein 1b
Authors:Nguyen, H.C, Frost, A.
Deposit date:2019-08-11
Release date:2020-04-08
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
6E8G
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BU of 6e8g by Molmil
CryoEM reconstruction of IST1-CHMP1B copolymer filament bound to ssDNA at 2.9 Angstrom resolution
Descriptor: Charged multivesicular body protein 1b, IST1 homolog
Authors:Talledge, N, Frost, A, McCullough, J.
Deposit date:2018-07-29
Release date:2018-08-15
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The ESCRT-III proteins IST1 and CHMP1B assemble around nucleic acids
Biorxiv, 2018
4TXR
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BU of 4txr by Molmil
Crystal structure of LIP5 N-terminal domain complexed with CHMP1B MIM and CHMP5 MIM
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Charged multivesicular body protein 1b, ...
Authors:Vild, C.J, Xu, Z.
Deposit date:2014-07-04
Release date:2015-02-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1 Å)
Cite:A Novel Mechanism of Regulating the ATPase VPS4 by Its Cofactor LIP5 and the Endosomal Sorting Complex Required for Transport (ESCRT)-III Protein CHMP5.
J.Biol.Chem., 290, 2015
3JC1
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BU of 3jc1 by Molmil
Electron cryo-microscopy of the IST1-CHMP1B ESCRT-III copolymer
Descriptor: Charged multivesicular body protein 1b, Increased Sodium Tolerance 1 (IST1)
Authors:McCullough, J, Clippinger, A.K, Talledge, N, Skowyra, M.L, Saunders, M.G, Naismith, T.V, Colf, L.A, Afonine, P, Arthur, C, Sundquist, W.I, Hanson, P.I, Frost, A.
Deposit date:2015-11-09
Release date:2015-12-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure and membrane remodeling activity of ESCRT-III helical polymers.
Science, 350, 2015
5VO5
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BU of 5vo5 by Molmil
Crystal structure of Lgd-Shrub complex, single chain fusion
Descriptor: Coiled-coil and C2 domain-containing protein 1-like,GH13992p
Authors:McMillan, B.J, Seegar, T.C.M, Blacklow, S.C.
Deposit date:2017-05-02
Release date:2017-06-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural Basis for Regulation of ESCRT-III Complexes by Lgd.
Cell Rep, 19, 2017
2LUH
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BU of 2luh by Molmil
NMR structure of the Vta1-Vps60 complex
Descriptor: Vacuolar protein sorting-associated protein VTA1, Vacuolar protein-sorting-associated protein 60
Authors:Yang, Z, Vild, C, Ju, J, Zhang, X, Liu, J, Shen, J, Zhao, B, Lan, W, Gong, F, Liu, M, Cao, C, Xu, Z.
Deposit date:2012-06-13
Release date:2012-11-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis of Molecular Recognition between ESCRT-III-like Protein Vps60 and AAA-ATPase Regulator Vta1 in the Multivesicular Body Pathway.
J.Biol.Chem., 287, 2012
2LXM
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BU of 2lxm by Molmil
Lip5-chmp5
Descriptor: Charged multivesicular body protein 5, Vacuolar protein sorting-associated protein VTA1 homolog
Authors:Skalicky, J.J, Sundquist, W.I.
Deposit date:2012-08-29
Release date:2012-11-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Interactions of the Human LIP5 Regulatory Protein with Endosomal Sorting Complexes Required for Transport.
J.Biol.Chem., 287, 2012
6TZ4
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BU of 6tz4 by Molmil
CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B+IST1 (right-handed)
Descriptor: Charged multivesicular body protein 1b, IST1 homolog
Authors:Nguyen, H.C, Frost, A.
Deposit date:2019-08-10
Release date:2020-04-08
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
6TZ5
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BU of 6tz5 by Molmil
CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B+IST1 (left-handed)
Descriptor: Charged multivesicular body protein 1b, IST1 homolog
Authors:Nguyen, H.C, Frost, A.
Deposit date:2019-08-10
Release date:2020-04-08
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
3UM3
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BU of 3um3 by Molmil
Crystal structure of the Brox Bro1 domain in complex with the C-terminal tail of CHMP4B
Descriptor: BRO1 domain-containing protein BROX, Charged multivesicular body protein 4b
Authors:Jiang, J.S, Mu, R.L, Xiao, T.
Deposit date:2011-11-12
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B.
Structure, 20, 2012

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