9BGE
 
 | | Cryo-EM structure of mAb8-24 bound to 426c.WITO.TM.SOSIP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.WITO.TM.SOSIP, ... | | Authors: | Hurlburt, N.K, Pancera, M. | | Deposit date: | 2024-04-18 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Short CDRL1 in intermediate VRC01-like mAbs is not sufficient to overcome key glycan barriers on HIV-1 Env
To Be Published
|
|
9EZY
 | | Vibrio cholerae DdmD-DdmE holo complex | | Descriptor: | 14 nucleotide DNA guide with terminal 5' phosphate, Helicase/UvrB N-terminal domain-containing protein, MAGNESIUM ION, ... | | Authors: | Loeff, L, Jinek, M. | | Deposit date: | 2024-04-14 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (2.56 Å) | | Cite: | Molecular mechanism of plasmid elimination by the DdmDE defense system.
Science, 385, 2024
|
|
9CV9
 | | Bufavirus 1 at pH 4.0 | | Descriptor: | VP1 | | Authors: | Gulkis, M.C, McKenna, R, Bennett, A.D. | | Deposit date: | 2024-07-28 | | Release date: | 2024-08-28 | | Last modified: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes.
Viruses, 16, 2024
|
|
9BWT
 | | human sodium chloride cotransporter NCC S344E in the phosphorylation state and in complex with hydrochlorothiazide | | Descriptor: | 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, ADENOSINE-5'-TRIPHOSPHATE, Solute carrier family 12 member 3 | | Authors: | Cao, E.H, Zhao, Y.X. | | Deposit date: | 2024-05-21 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Structural bases for Na + -Cl - cotransporter inhibition by thiazide diuretic drugs and activation by kinases.
Nat Commun, 15, 2024
|
|
8YAX
 | |
9F1B
 | | Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | Authors: | Yudin, D, Scaiola, A, Ban, N. | | Deposit date: | 2024-04-18 | | Release date: | 2024-08-21 | | Last modified: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | NAC guides a ribosomal multienzyme complex for nascent protein processing.
Nature, 2024
|
|
9FFB
 | | ss-dsDNA-FANCD2-FANCI complex | | Descriptor: | DNA (5'-D(P*CP*GP*AP*TP*GP*TP*CP*TP*CP*TP*AP*GP*AP*CP*AP*GP*CP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*GP*CP*TP*GP*TP*CP*TP*AP*GP*AP*GP*AP*CP*AP*TP*CP*GP*AP*T)-3'), Fanconi anemia complementation group I, ... | | Authors: | Alcon, P, Passmore, L.A. | | Deposit date: | 2024-05-22 | | Release date: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | ss-dsDNA-FANCD2-FANCI complex
To Be Published
|
|
9BAP
 | | CryoEM structure of Apo-DIM2 | | Descriptor: | DNA (cytosine-5-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | Authors: | Song, J, Shao, Z. | | Deposit date: | 2024-04-04 | | Release date: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | CryoEM structure of Apo-DIM2
To Be Published
|
|
9F1C
 | | Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | Authors: | Yudin, D, Scaiola, A, Ban, N. | | Deposit date: | 2024-04-18 | | Release date: | 2024-08-21 | | Last modified: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | NAC guides a ribosomal multienzyme complex for nascent protein processing.
Nature, 2024
|
|
9FOF
 | |
9EQ5
 | |
8Y46
 | | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase bound to L-KDF or L-2,4-DKDF | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, L-2,4-diketo-3-deoxyfuconate, ... | | Authors: | Akagashi, M, Watanabe, S. | | Deposit date: | 2024-01-30 | | Release date: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (1.29 Å) | | Cite: | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase reveals a unique binding mode as a alpha-furanosyl hemiketal of substrates.
Sci Rep, 14, 2024
|
|
9FCJ
 | | USP1 bound to ML323 and ubiquitin conjugated to FANCD2 (ordered subset, focused refinement) | | Descriptor: | 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-[[4-(1,2,3-triazol-1-yl)phenyl]methyl]pyrimidin-4-amine, Polyubiquitin-C, Ubiquitin carboxyl-terminal hydrolase 1, ... | | Authors: | Rennie, M.L, Gundogdu, M, Walden, H. | | Deposit date: | 2024-05-15 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural and Biochemical Insights into the Mechanism of Action of the Clinical USP1 Inhibitor, KSQ-4279.
J.Med.Chem., 2024
|
|
9B71
 | | Cryo-EM structure of MraY in complex with analogue 3 | | Descriptor: | (2~{S},3~{S})-3-[(2~{S},3~{R},4~{S},5~{R})-5-(aminomethyl)-3,4-bis(oxidanyl)oxolan-2-yl]oxy-3-[(2~{S},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]-2-[[4-[[[(2~{S})-5-carbamimidamido-2-(hexadecanoylamino)pentanoyl]amino]methyl]phenyl]methylamino]propanoic acid, MraYAA Nanobody, Phospho-N-acetylmuramoyl-pentapeptide-transferase | | Authors: | Hao, A, Lee, S.-Y. | | Deposit date: | 2024-03-26 | | Release date: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target.
Nat Commun, 15, 2024
|
|
8YEJ
 | | Cryo-EM structure of the channelrhodopsin GtCCR2 focused on the monomer | | Descriptor: | GtCCR2, RETINAL | | Authors: | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | | Deposit date: | 2024-02-22 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4
Mol.Cell, 2024
|
|
9FHP
 | |
9B9R
 | |
9BNI
 | |
8Y6A
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2 and S309 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | Authors: | Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F. | | Deposit date: | 2024-02-02 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
|
|
9EOC
 | |
8Y1L
 | |
9ETU
 | | Archaellum filament from the Halobacterium salinarum deltaAgl27 strain | | Descriptor: | 3-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-beta-D-glucopyranuronic acid-(1-4)-beta-D-glucopyranose, Archaellin | | Authors: | Grossman-Haham, I, Shahar, A. | | Deposit date: | 2024-03-27 | | Release date: | 2024-07-17 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Perturbed N-glycosylation of Halobacterium salinarum archaellum filaments leads to filament bundling and compromised cell motility.
Nat Commun, 15, 2024
|
|
9EUU
 | | Structure of recombinant alpha-synuclein fibrils 1B capable of seeding GCIs in vivo | | Descriptor: | Alpha-synuclein | | Authors: | Burger, D, Kashyrina, M, Lewis, A, De Nuccio, F, Mohammed, I, de La Seigliere, H, van den Heuvel, L, Feuillie, C, Verchere, J, Berbon, M, Arotcarena, M, Retailleau, A, Bezard, E, Laferriere, F, Loquet, A, Bousset, L, Baron, T, Lofrumento, D.D, De Giorgi, F, Stahlberg, H, Ichas, F. | | Deposit date: | 2024-03-28 | | Release date: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (1.93 Å) | | Cite: | Multiple System Atrophy: Insights from aSyn Fibril Structure
To Be Published
|
|
9IIW
 | |
9FBV
 | |
