8Y93
| Structure of NET-Amitriptyline in outward-open state | Descriptor: | Amitriptyline, CHLORIDE ION, SODIUM ION, ... | Authors: | Zhang, H, Xu, E.H, Jiang, Y. | Deposit date: | 2024-02-06 | Release date: | 2024-05-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Dimerization and antidepressant recognition at noradrenaline transporter. Nature, 630, 2024
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8XOB
| VMAT2 protonated state | Descriptor: | Synaptic vesicular amine transporter,transporter B | Authors: | Jiang, D.H, Wu, D. | Deposit date: | 2023-12-31 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | VMAT2 protonated state To Be Published
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8YLZ
| Structure of a cis-Geranylfarnesyl Diphosphate Synthase from Streptomyces clavuligerus | Descriptor: | Isoprenyl transferase | Authors: | Li, F.R, Wang, Q.L, Pan, X.M, Dong, L.B. | Deposit date: | 2024-03-07 | Release date: | 2024-05-08 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Discovery, Structure, and Engineering of a cis-Geranylfarnesyl Diphosphate Synthase. Angew.Chem.Int.Ed.Engl., 63, 2024
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7WLW
| X-ray structure of thermostabilized Drosophila dopamine transporter with GABA transporter1-like substitutions in the binding site, in complex with SKF89976a | Descriptor: | (3S)-1-(4,4-diphenylbut-3-enyl)piperidine-3-carboxylic acid, Antibody Fragment heavy chain, Antibody fragment light chain, ... | Authors: | Penmatsa, A, Joseph, D. | Deposit date: | 2022-01-13 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter. Embo J., 41, 2022
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8Y95
| Structure of NET-NE in Occluded state | Descriptor: | CHLORIDE ION, Noradrenaline, SODIUM ION, ... | Authors: | Zhang, H, Xu, H.E, Jiang, Y. | Deposit date: | 2024-02-06 | Release date: | 2024-05-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Dimerization and antidepressant recognition at noradrenaline transporter. Nature, 630, 2024
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7WGD
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7W6Z
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8Y8Z
| Structure of NET-Maprotiline in outward-open state | Descriptor: | CHLORIDE ION, SODIUM ION, Sodium-dependent noradrenaline transporter, ... | Authors: | Zhang, H, Xu, E.H, Jiang, Y. | Deposit date: | 2024-02-06 | Release date: | 2024-05-29 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Dimerization and antidepressant recognition at noradrenaline transporter. Nature, 630, 2024
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8Y94
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8WU7
| Structure of a cis-Geranylfarnesyl Diphosphate Synthase from Streptomyces clavuligerus | Descriptor: | Isoprenyl transferase | Authors: | Li, F.R, Wang, Q.L, Pan, X.M, Dong, L.B. | Deposit date: | 2023-10-20 | Release date: | 2024-05-08 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Discovery, Structure, and Engineering of a cis-Geranylfarnesyl Diphosphate Synthase. Angew.Chem.Int.Ed.Engl., 63, 2024
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8XO9
| VMAT2 complex with noradrenaline in cytosol-facing state | Descriptor: | Noradrenaline, Synaptic vesicular amine transporter,Synaptic vesicular amine transporter,transporter A | Authors: | Jiang, D.H, Wu, D. | Deposit date: | 2023-12-31 | Release date: | 2024-05-08 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | VMAT2 complex with noradrenaline in cytosol-facing state To Be Published
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7WGT
| X-ray structure of thermostabilized Drosophila dopamine transporter with GABA transporter1-like substitutions in the binding site, in complex with NO711. | Descriptor: | 1-(2-{[(diphenylmethylidene)amino]oxy}ethyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid, Antibody fragment (9D5) heavy chain, Antibody fragment (9D5) light chain, ... | Authors: | Joseph, D, Penmatsa, A. | Deposit date: | 2021-12-28 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter. Embo J., 41, 2022
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7W6X
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7WHG
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7W6Y
| Crystal structure of Kangiella koreensis RseP orthologue in complex with batimastat in space group P1 | Descriptor: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, Anti sigma-E protein, RseA, ... | Authors: | Imaizumi, Y, Takanuki, K, Nogi, T. | Deposit date: | 2021-12-02 | Release date: | 2022-09-07 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP. Sci Adv, 8, 2022
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8YF0
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8YF1
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8XH7
| Structure of EBV LMP1 oligomer | Descriptor: | Latent membrane protein 1 | Authors: | Gao, P, Huang, J.F. | Deposit date: | 2023-12-17 | Release date: | 2024-06-26 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Assembly and activation of EBV latent membrane protein 1. Cell, 187, 2024
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8X55
| BA.2.86 Spike Trimer with T356K mutation (3 RBD down) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Yue, C, Liu, P. | Deposit date: | 2023-11-16 | Release date: | 2024-06-26 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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7UX1
| EcMscK in an Open Conformation | Descriptor: | Mechanosensitive channel MscK | Authors: | Mount, J.W, Yuan, P. | Deposit date: | 2022-05-04 | Release date: | 2022-11-23 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structural basis for mechanotransduction in a potassium-dependent mechanosensitive ion channel. Nat Commun, 13, 2022
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8XB4
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8XH6
| Structure of EBV LMP1 dimer | Descriptor: | Latent membrane protein 1 | Authors: | Gao, P, Huang, J.F. | Deposit date: | 2023-12-17 | Release date: | 2024-06-26 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Assembly and activation of EBV latent membrane protein 1. Cell, 187, 2024
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8X4Z
| BA.2.86 Spike Trimer with ins483V mutation (3 RBD down) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Yue, C, Liu, P. | Deposit date: | 2023-11-16 | Release date: | 2024-06-26 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8X56
| BA.2.86 Spike Trimer with T356K mutation (1 RBD up) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Yue, C, Liu, P. | Deposit date: | 2023-11-16 | Release date: | 2024-06-26 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.93 Å) | Cite: | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8Y66
| Cryo-EM structure of human urate transporter GLUT9 bound to inhibitor apigenin | Descriptor: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Solute carrier family 2, facilitated glucose transporter member 9 | Authors: | Pan, X.J, Shen, Z.L, Xu, L, Huang, G.X.Y. | Deposit date: | 2024-02-01 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Structural basis for urate recognition and apigenin inhibition of human GLUT9. Nat Commun, 15, 2024
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