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3B6S
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Crystal Structure of hla-b*2705 Complexed with the Citrullinated Vasoactive Intestinal Peptide Type 1 Receptor (vipr) Peptide (residues 400-408)
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ...
Authors:Beltrami, A, Rossmann, M, Fiorillo, M.T, Sorrentino, R, Saenger, W, Ziegler, A, Uchanska-Ziegler, A.
Deposit date:2007-10-29
Release date:2008-07-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Citrullination-dependent Differential Presentation of a Self-peptide by HLA-B27 Subtypes.
J.Biol.Chem., 283, 2008
3MYJ
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BU of 3myj by Molmil
Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) (R1Y) peptide variant.
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-05-10
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: Implications for WT1-based cancer therapeutics.
Mol.Immunol., 47, 2010
3MV8
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BU of 3mv8 by Molmil
Crystal Structure of the TK3-Gln55His TCR in complex with HLA-B*3501/HPVG
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
Authors:Gras, S, Chen, Z, Miles, J.J, Liu, Y.C, Bell, M.J, Sullivan, L.C, Kjer-Nielsen, L, Brennan, R.M, Burrows, J.M, Neller, M.A, Khanna, R, Purcell, A.W, Brooks, A.G, McCluskey, J, Rossjohn, J, Burrows, S.R.
Deposit date:2010-05-03
Release date:2010-06-09
Last modified:2011-07-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Allelic polymorphism in the T cell receptor and its impact on immune responses
J.Exp.Med., 207, 2010
3C6L
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Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR 2W20
Descriptor: 3K peptide, Linker,and H-2 class II histocompatibility antigen (A beta chain), CALCIUM ION, ...
Authors:Dai, S.
Deposit date:2008-02-04
Release date:2008-04-29
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules.
Immunity, 28, 2008
3C5Z
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Crystal structure of mouse MHC class II I-Ab/3K peptide complexed with mouse TCR B3K506
Descriptor: 3K peptide, Linker, and H-2 class II histocompatibility antigen (A beta chain), ...
Authors:Dai, S, Kappler, J.
Deposit date:2008-02-01
Release date:2008-04-29
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules.
Immunity, 28, 2008
3BZF
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BU of 3bzf by Molmil
The human non-classical major histocompatibility complex molecule HLA-E
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
Authors:Hoare, H.L, Sullivan, L.C, Ely, L.K, Beddoe, T, Henderson, K.N, Lin, J, Clements, C.S, Reid, H.H, Brooks, A.G, Rossjohn, J.
Deposit date:2008-01-17
Release date:2008-04-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors
J.Mol.Biol., 377, 2008
3CC5
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BU of 3cc5 by Molmil
H-2Db complex with human gp100
Descriptor: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
Authors:Badia-Martinez, D, Achour, A.
Deposit date:2008-02-24
Release date:2009-03-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.
Cancer Res., 69, 2009
3BP7
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BU of 3bp7 by Molmil
The high resolution crystal structure of HLA-B*2709 in complex with a Cathepsin A signal sequence peptide, pCatA
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Kumar, P, Vahedi-Faridi, A, Saenger, W, Uchanska-Ziegler, B, Ziegler, A.
Deposit date:2007-12-18
Release date:2008-12-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens
J.Biol.Chem., 284, 2009
3BH9
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Crystal Structure of RTY Phosphopeptide Bound to Human Class I MHC HLA-A2
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Mohammed, F, Cobbold, M, Zarling, A.L, Salim, M, Barrett-Wilt, G.A, Shabanowitz, J, Hunt, D.F, Engelhard, V.H, Willcox, B.E.
Deposit date:2007-11-28
Release date:2008-10-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self
Nat.Immunol., 9, 2008
3PWJ
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Human Class I MHC HLA-A2 in complex with the HuD (G2L,I9V) peptide variant
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-12-08
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3PGC
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BU of 3pgc by Molmil
Crystal Structure of HLA-DR1 with CLIP106-120, flipped peptide orientation
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, HLA class II histocompatibility antigen gamma chain, ...
Authors:Gunther, S, Schlundt, A, Sticht, J, Roske, Y, Heinemann, U, Wiesmuller, K.-H, Jung, G, Falk, K, Rotzschke, O, Freund, C.
Deposit date:2010-11-01
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PGD
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Crystal Structure of HLA-DR1 with CLIP106-120, canonical peptide orientation
Descriptor: HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, ...
Authors:Gunther, S, Schlundt, A, Sticht, J, Roske, Y, Heinemann, U, Wiesmuller, K.-H, Jung, G, Falk, K, Rotzschke, O, Freund, C.
Deposit date:2010-11-01
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PGF
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BU of 3pgf by Molmil
Crystal structure of maltose bound MBP with a conformationally specific synthetic antigen binder (sAB)
Descriptor: GLYCEROL, IMIDAZOLE, Maltose-binding periplasmic protein, ...
Authors:Kossiakoff, A.A, Duguid, E.M, Sandstrom, A.
Deposit date:2010-11-01
Release date:2011-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins.
Nat.Struct.Mol.Biol., 18, 2011
3BAE
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BU of 3bae by Molmil
Crystal structure of Fab WO2 bound to the N terminal domain of Amyloid beta peptide (1-28)
Descriptor: Amyloid Beta Peptide, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa
Authors:Miles, L.A, Wun, K.S, Crespi, G.A, Parker, M.W.
Deposit date:2007-11-07
Release date:2008-04-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.593 Å)
Cite:Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
J.Mol.Biol., 377, 2008
3PWU
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BU of 3pwu by Molmil
An immmunodominant CTL epitope from rinderpest virus presented by cattle MHC class I molecule N*01801(BoLA-A11)
Descriptor: Beta-2-microglobulin, IPA from Hemagglutinin glycoprotein, MHC class I antigen
Authors:Li, X, Liu, J, Qi, J, Gao, F, Li, Q, Li, X, Zhang, N, Xia, C, Gao, G.F.
Deposit date:2010-12-09
Release date:2011-08-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides
J.Virol., 85, 2011
3BH8
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BU of 3bh8 by Molmil
Crystal Structure of RQA_M Phosphopeptide Bound to HUMAN Class I MHC HLA-A2
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Mohammed, F, Cobbold, M, Zarling, A.L, Salim, M, Barrett-Wilt, G.A, Shabanowitz, J, Hunt, D.F, Engelhard, V.H, Willcox, B.E.
Deposit date:2007-11-28
Release date:2008-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self
Nat.Immunol., 9, 2008
3BHB
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BU of 3bhb by Molmil
Crystal Structure of KMD Phosphopeptide Bound to Human Class I MHC HLA-A2
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Mohammed, F, Cobbold, M, Zarling, A.L, Salim, M, Barrett-Wilt, G.A, Shabanowitz, J, Hunt, D.F, Engelhard, V.H, Willcox, B.E.
Deposit date:2007-11-28
Release date:2008-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self
Nat.Immunol., 9, 2008
3BO8
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BU of 3bo8 by Molmil
The High Resolution Crystal Structure of HLA-A1 Complexed with the MAGE-A1 Peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Kumar, P, Vahedi-Faridi, A, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
Deposit date:2007-12-17
Release date:2008-12-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificity
Protein Sci., 18, 2009
3PWL
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BU of 3pwl by Molmil
Human Class I MHC HLA-A2 in complex with the HuD peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-12-08
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3C5J
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BU of 3c5j by Molmil
Crystal structure of HLA DR52c
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Elongation factor 1-alpha 2, HLA class II histocompatibility antigen, ...
Authors:Dai, S, Kappler, J.W.
Deposit date:2008-01-31
Release date:2008-08-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles.
Proc.Natl.Acad.Sci.USA, 105, 2008
3BVN
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BU of 3bvn by Molmil
High resolution crystal structure of HLA-B*1402 in complex with the latent membrane protein 2 peptide (LMP2) of Epstein-Barr virus
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B*1402 alpha chain, ...
Authors:Kumar, P, Vahedi-Faridi, A, Saenger, W, Uchanska-Ziegler, B, Ziegler, A.
Deposit date:2008-01-07
Release date:2009-02-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens
J.Biol.Chem., 284, 2009
3M1B
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BU of 3m1b by Molmil
Crystal structure of human FcRn with a dimeric peptide inhibitor
Descriptor: Beta-2-microglobulin, DIMERIC PEPTIDE INHIBITOR, IgG receptor FcRn large subunit p51
Authors:Mezo, A.R, Sridhar, V, Badger, J, Sakorafas, P, Nienaber, V.
Deposit date:2010-03-04
Release date:2010-06-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:X-ray crystal structures of monomeric and dimeric peptide inhibitors in complex with the human neonatal Fc receptor, FcRn.
J.Biol.Chem., 285, 2010
3MRK
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BU of 3mrk by Molmil
Crystal Structure of MHC class I HLA-A2 molecule complexed with AFP137 nonapeptide
Descriptor: 9-meric peptide from Alpha-fetoprotein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Gras, S, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D.
Deposit date:2010-04-29
Release date:2011-05-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of MHC class I HLA-A2 molecule complexed with AFP137 nonapeptide
To be Published
3M17
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BU of 3m17 by Molmil
Crystal structure of human FcRn with a monomeric peptide inhibitor
Descriptor: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, monomeric peptide inhibitor
Authors:Mezo, A.R, Sridhar, V, Badger, J, Sakorafas, P, Nienaber, V.
Deposit date:2010-03-04
Release date:2010-06-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:X-ray crystal structures of monomeric and dimeric peptide inhibitors in complex with the human neonatal Fc receptor, FcRn.
J.Biol.Chem., 285, 2010
3O4L
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Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BSLF2/BMLF1 protein, Beta-2-microglobulin, ...
Authors:Miles, J.J, Bulek, A.M, Cole, D.K, Gostick, E, Schauenburg, J.A, Dolton, G, Venturi, V, Davenport, M.P, Tan, M.P, Burrows, S.R, Wooldridge, L, Price, D.A, Rizkallah, P.J, Sewell, A.K.
Deposit date:2010-07-27
Release date:2011-01-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection.
Plos Pathog., 6, 2010

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