8RU2
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![BU of 8ru2 by Molmil](/molmil-images/mine/8ru2) | Structure of the F-actin barbed end bound by formin mDia1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | Deposit date: | 2024-01-29 | Release date: | 2024-04-10 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
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8RTY
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![BU of 8rty by Molmil](/molmil-images/mine/8rty) | Structure of the F-actin barbed end bound by Cdc12 and profilin (ring complex) at a resolution of 6.3 Angstrom | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | Deposit date: | 2024-01-29 | Release date: | 2024-04-10 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (6.25 Å) | Cite: | Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
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6KN7
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![BU of 6kn7 by Molmil](/molmil-images/mine/6kn7) | Structure of human cardiac thin filament in the calcium free state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Fujii, T, Yamada, Y, Namba, K. | Deposit date: | 2019-08-03 | Release date: | 2020-01-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Cardiac muscle thin filament structures reveal calcium regulatory mechanism. Nat Commun, 11, 2020
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6KN8
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![BU of 6kn8 by Molmil](/molmil-images/mine/6kn8) | Structure of human cardiac thin filament in the calcium bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Fujii, T, Yamada, Y, Namba, K. | Deposit date: | 2019-08-03 | Release date: | 2020-01-15 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Cardiac muscle thin filament structures reveal calcium regulatory mechanism. Nat Commun, 11, 2020
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6KW3
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![BU of 6kw3 by Molmil](/molmil-images/mine/6kw3) | The ClassA RSC-Nucleosome Complex | Descriptor: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | Authors: | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | Deposit date: | 2019-09-05 | Release date: | 2019-11-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (7.13 Å) | Cite: | Structure of the RSC complex bound to the nucleosome. Science, 366, 2019
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1ESV
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![BU of 1esv by Molmil](/molmil-images/mine/1esv) | COMPLEX BETWEEN LATRUNCULIN A:RABBIT MUSCLE ALPHA ACTIN:HUMAN GELSOLIN DOMAIN 1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ALPHA ACTIN, CALCIUM ION, ... | Authors: | Morton, W.M, Ayscough, K.A, McLaughlin, P.J. | Deposit date: | 2000-04-11 | Release date: | 2000-07-19 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Latrunculin alters the actin-monomer subunit interface to prevent polymerization. Nat.Cell Biol., 2, 2000
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2BTF
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![BU of 2btf by Molmil](/molmil-images/mine/2btf) | THE STRUCTURE OF CRYSTALLINE PROFILIN-BETA-ACTIN | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, BETA-ACTIN, PROFILIN, ... | Authors: | Schutt, C.E, Myslik, J.C, Rozycki, M.D, Goonesekere, N.C.W. | Deposit date: | 1994-01-18 | Release date: | 1994-06-22 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The structure of crystalline profilin-beta-actin. Nature, 365, 1993
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5Y81
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![BU of 5y81 by Molmil](/molmil-images/mine/5y81) | NuA4 TEEAA sub-complex | Descriptor: | Actin, Actin-related protein 4, Chromatin modification-related protein EAF1, ... | Authors: | Wang, X, Cai, G. | Deposit date: | 2017-08-18 | Release date: | 2018-04-18 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex Nat Commun, 9, 2018
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6X5Z
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![BU of 6x5z by Molmil](/molmil-images/mine/6x5z) | Bovine Cardiac Myosin in Complex with Chicken Skeletal Actin and Human Cardiac Tropomyosin in the Rigor State | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Doran, M.H, Lehman, W, Rynkiewicz, M.J, Bullitt, E. | Deposit date: | 2020-05-27 | Release date: | 2020-07-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.24 Å) | Cite: | Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments. Biophys.J., 119, 2020
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6YP9
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![BU of 6yp9 by Molmil](/molmil-images/mine/6yp9) | Rabbit muscle actin in complex with ADF-H and ATP-ATTO-488 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Kogan, K, Kotila, T, Lappalainen, P. | Deposit date: | 2020-04-15 | Release date: | 2020-12-09 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.564 Å) | Cite: | A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics. Nat Commun, 12, 2021
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5YEE
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![BU of 5yee by Molmil](/molmil-images/mine/5yee) | |
5YPU
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![BU of 5ypu by Molmil](/molmil-images/mine/5ypu) | Crystal structure of an actin monomer in complex with the nucleator Cordon-Bleu MET72NLE WH2-motif peptide | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Scipion, C.P.M, Wongsantichon, J, Ferrer, F.J, Yuen, T.Y, Robinson, R.C. | Deposit date: | 2017-11-03 | Release date: | 2018-09-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural evidence for the roles of divalent cations in actin polymerization and activation of ATP hydrolysis Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1DEJ
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![BU of 1dej by Molmil](/molmil-images/mine/1dej) | CRYSTAL STRUCTURE OF A DICTYOSTELIUM/TETRAHYMENA CHIMERA ACTIN (MUTANT 646: Q228K/T229A/A230Y/A231K/S232E/E360H) IN COMPLEX WITH HUMAN GELSOLIN SEGMENT 1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CHIMERIC ACTIN, ... | Authors: | Matsuura, Y, Stewart, M, Kawamoto, M, Kamiya, N, Saeki, K, Yasunaga, T, Wakabayashi, T. | Deposit date: | 1999-11-15 | Release date: | 2000-03-01 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the higher Ca(2+)-activation of the regulated actin-activated myosin ATPase observed with Dictyostelium/Tetrahymena actin chimeras. J.Mol.Biol., 296, 2000
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6YW6
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![BU of 6yw6 by Molmil](/molmil-images/mine/6yw6) | Cryo-EM structure of the ARP2/3 1B5CL isoform complex. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ARPC1B, Actin-related protein 2, ... | Authors: | von Loeffelholz, O, Moores, C, Purkiss, A. | Deposit date: | 2020-04-29 | Release date: | 2020-07-22 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms. Biol Open, 9, 2020
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6YW7
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![BU of 6yw7 by Molmil](/molmil-images/mine/6yw7) | Cryo-EM structure of the ARP2/3 1A5C isoform complex. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ... | Authors: | von Loeffelholz, O, Moores, C, Purkiss, A. | Deposit date: | 2020-04-29 | Release date: | 2020-07-22 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms. Biol Open, 9, 2020
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5WFN
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![BU of 5wfn by Molmil](/molmil-images/mine/5wfn) | Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT) | Descriptor: | Actin-5C, Leiomodin-2, MAGNESIUM ION, ... | Authors: | Yurtsever, Z, Eck, M.J, Dominguez, R. | Deposit date: | 2017-07-12 | Release date: | 2017-08-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of leiomodin 2 in complex with actin: a structural and functional reexamination Biophys.J., 113, 2017
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2D1K
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![BU of 2d1k by Molmil](/molmil-images/mine/2d1k) | Ternary complex of the WH2 domain of mim with actin-dnase I | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Chereau, D, Kerff, F, Dominguez, R. | Deposit date: | 2005-08-26 | Release date: | 2006-09-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the actin-binding function of missing-in-metastasis Structure, 15, 2007
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5YU8
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![BU of 5yu8 by Molmil](/molmil-images/mine/5yu8) | Cofilin decorated actin filament | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Tanaka, K, Narita, A. | Deposit date: | 2017-11-21 | Release date: | 2018-05-23 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis for cofilin binding and actin filament disassembly Nat Commun, 9, 2018
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2FF3
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![BU of 2ff3 by Molmil](/molmil-images/mine/2ff3) | Crystal structure of Gelsolin domain 1:N-wasp V2 motif hybrid in complex with actin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Xue, B, Aguda, A.H, Robinson, R.C. | Deposit date: | 2005-12-19 | Release date: | 2006-03-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Structural Basis of Actin Interaction with Multiple WH2/beta-Thymosin Motif-Containing Proteins Structure, 14, 2006
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2FF6
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![BU of 2ff6 by Molmil](/molmil-images/mine/2ff6) | Crystal structure of Gelsolin domain 1:ciboulot domain 2 hybrid in complex with actin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Aguda, A.H, Xue, B, Robinson, R.C. | Deposit date: | 2005-12-19 | Release date: | 2006-03-21 | Last modified: | 2018-05-23 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The Structural Basis of Actin Interaction with Multiple WH2/beta-Thymosin Motif-Containing Proteins Structure, 14, 2006
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1EQY
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![BU of 1eqy by Molmil](/molmil-images/mine/1eqy) | COMPLEX BETWEEN RABBIT MUSCLE ALPHA-ACTIN: HUMAN GELSOLIN DOMAIN 1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ALPHA ACTIN, CALCIUM ION, ... | Authors: | McLaughlin, P.J, Gooch, J.T, Mannherz, H.G, Weeds, A.G. | Deposit date: | 2000-04-06 | Release date: | 2000-05-03 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of gelsolin segment 1-actin complex and the mechanism of filament severing. Nature, 364, 1993
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1H1V
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![BU of 1h1v by Molmil](/molmil-images/mine/1h1v) | gelsolin G4-G6/actin complex | Descriptor: | ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | Authors: | Choe, H, Burtnick, L.D, Mejillano, M, Yin, H.L, Robinson, R.C, Choe, S. | Deposit date: | 2002-07-23 | Release date: | 2003-01-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | The Calcium Activation of Gelsolin:Insights from the 3A Structure of the G4-G6/Actin Complex J.Mol.Biol., 324, 2002
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1HLU
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![BU of 1hlu by Molmil](/molmil-images/mine/1hlu) | STRUCTURE OF BOVINE BETA-ACTIN-PROFILIN COMPLEX WITH ACTIN BOUND ATP PHOSPHATES SOLVENT ACCESSIBLE | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, BETA-ACTIN, CALCIUM ION, ... | Authors: | Chik, J.K, Lindberg, U, Schutt, C.E. | Deposit date: | 1997-05-30 | Release date: | 1997-10-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | The structure of an open state of beta-actin at 2.65 A resolution. J.Mol.Biol., 263, 1996
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7C2G
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![BU of 7c2g by Molmil](/molmil-images/mine/7c2g) | |
7R94
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![BU of 7r94 by Molmil](/molmil-images/mine/7r94) | T-Plastin-F-actin complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Mei, L, Alushin, G.M. | Deposit date: | 2021-06-28 | Release date: | 2022-07-06 | Last modified: | 2022-09-21 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural mechanism for bidirectional actin cross-linking by T-plastin. Proc.Natl.Acad.Sci.USA, 119, 2022
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