2IK1
 
 | | Yeast inorganic pyrophosphatase variant Y93F with magnesium and phosphate | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Inorganic pyrophosphatase, MAGNESIUM ION | | Authors: | Oksanen, E, Ahonen, A.K, Tuominen, H, Tuominen, V, Lahti, R, Goldman, A, Heikinheimo, P. | | Deposit date: | 2006-10-02 | | Release date: | 2007-02-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
Biochemistry, 46, 2007
|
|
2IK9
 | | Yeast inorganic pyrophosphatase variant D152E with magnesium and phosphate | | Descriptor: | Inorganic pyrophosphatase, MAGNESIUM ION, PHOSPHATE ION | | Authors: | Oksanen, E, Ahonen, A.K, Tuominen, H, Tuominen, V, Lahti, R, Goldman, A, Heikinheimo, P. | | Deposit date: | 2006-10-02 | | Release date: | 2007-02-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
Biochemistry, 46, 2007
|
|
2IPJ
 | | Crystal structure of h3alpha-hydroxysteroid dehydrogenase type 3 mutant Y24A in complex with NADP+ and epi-testosterone | | Descriptor: | (10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE, 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member C2, ... | | Authors: | Faucher, F, Cantin, L, Pereira de Jesus-Tran, K, Luu-the, V, Labrie, F, Breton, R. | | Deposit date: | 2006-10-12 | | Release date: | 2007-06-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Mouse 17alpha-Hydroxysteroid Dehydrogenase (AKR1C21) Binds Steroids Differently from other Aldo-keto Reductases: Identification and Characterization of Amino Acid Residues Critical for Substrate Binding.
J.Mol.Biol., 369, 2007
|
|
7FJM
 | | Cryo EM structure of lysosomal ATPase | | Descriptor: | Polyamine-transporting ATPase 13A2 | | Authors: | Zhang, S.S. | | Deposit date: | 2021-08-04 | | Release date: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structures and transport mechanism of human P5B type ATPase ATP13A2.
Cell Discov, 7, 2021
|
|
2IPW
 | | Crystal Structure of C298A W219Y Aldose Reductase complexed with Dichlorophenylacetic acid | | Descriptor: | (2,6-DICHLOROPHENYL)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Harrison, D.H.T, Pape, E, Brownlee, J.M. | | Deposit date: | 2006-10-12 | | Release date: | 2006-11-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.
Bioorg.Chem., 34, 2006
|
|
2J2F
 | | The T199D Mutant of Stearoyl Acyl Carrier Protein Desaturase from Ricinus Communis (Castor Bean) | | Descriptor: | ACYL-[ACYL-CARRIER-PROTEIN] DESATURASE, FE (III) ION | | Authors: | Guy, J.E, Abreu, I.A, Moche, M, Lindqvist, Y, Whittle, E, Shanklin, J. | | Deposit date: | 2006-08-16 | | Release date: | 2006-10-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | A Single Mutation in the Castor {Delta}9-18:0- Desaturase Changes Reaction Partitioning from Desaturation to Oxidase Chemistry.
Proc.Natl.Acad.Sci.USA, 103, 2006
|
|
2IQD
 | | Crystal Structure of Aldose Reductase complexed with Lipoic Acid | | Descriptor: | Aldose reductase, LIPOIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Harrison, D.H.T, Carlson, E, Pape, E, Brownlee, J.M. | | Deposit date: | 2006-10-13 | | Release date: | 2006-11-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.
Bioorg.Chem., 34, 2006
|
|
2ISF
 | |
2J83
 | | Ulilysin metalloprotease in complex with batimastat. | | Descriptor: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, CALCIUM ION, GLYCEROL, ... | | Authors: | Garcia-Castellanos, R, Tallant, C, Marrero, A, Sola, M, Baumann, U, Gomis-Ruth, F.X. | | Deposit date: | 2006-10-18 | | Release date: | 2006-12-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Substrate Specificity of a Metalloprotease of the Pappalysin Family Revealed by an Inhibitor and a Product Complex.
Arch.Biochem.Biophys., 457, 2007
|
|
7EPC
 | | Cryo-EM structure of inactive mGlu7 homodimer | | Descriptor: | Isoform 3 of Metabotropic glutamate receptor 7 | | Authors: | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | | Deposit date: | 2021-04-26 | | Release date: | 2021-06-23 | | Last modified: | 2021-07-07 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structures of human mGlu2 and mGlu7 homo- and heterodimers.
Nature, 594, 2021
|
|
7EPA
 | | Cryo-EM structure of inactive mGlu2 homodimer | | Descriptor: | Metabotropic glutamate receptor 2 | | Authors: | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | | Deposit date: | 2021-04-26 | | Release date: | 2021-06-23 | | Last modified: | 2021-07-07 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structures of human mGlu2 and mGlu7 homo- and heterodimers.
Nature, 594, 2021
|
|
2IRF
 | | CRYSTAL STRUCTURE OF AN IRF-2/DNA COMPLEX. | | Descriptor: | DNA (5'-D(*TP*TP*CP*AP*CP*TP*TP*TP*CP*AP*CP*(5IU)P*T)-3'), DNA (5'-D(P*AP*AP*GP*TP*GP*AP*AP*AP*GP*(5IU)P*GP*A)-3'), INTERFERON REGULATORY FACTOR 2, ... | | Authors: | Fujii, Y, Shimizu, T, Kusumoto, M, Kyogoku, Y, Taniguchi, T, Hakoshima, T. | | Deposit date: | 1999-05-30 | | Release date: | 1999-10-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences.
EMBO J., 18, 1999
|
|
7EPB
 | | Cryo-EM structure of LY354740-bound mGlu2 homodimer | | Descriptor: | (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid, Anti-RON nanobody, Metabotropic glutamate receptor 2 | | Authors: | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | | Deposit date: | 2021-04-26 | | Release date: | 2021-06-23 | | Last modified: | 2021-07-07 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structures of human mGlu2 and mGlu7 homo- and heterodimers.
Nature, 594, 2021
|
|
2ISI
 | |
7ETW
 | | Cryo-EM structure of Scap/Insig complex in the present of digitonin. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Digitonin, Insulin-induced gene 2 protein, ... | | Authors: | Yan, R, Cao, P, Song, W, Li, Y, Wang, T, Qian, H, Yan, C, Yan, N. | | Deposit date: | 2021-05-14 | | Release date: | 2021-06-23 | | Last modified: | 2022-03-02 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis for sterol sensing by Scap and Insig
Cell Rep, 35, 2021
|
|
7EZZ
 | | Crystal structure of Salmonella typhi outer membrane phospholipase (OMPLA) dimer with bound calcium | | Descriptor: | CALCIUM ION, DODECANE, Phospholipase A1, ... | | Authors: | Perumal, P, Raina, R, Sreeshma, N.S, Arockiasamy, A, Sundarabaalaji, N. | | Deposit date: | 2021-06-02 | | Release date: | 2021-06-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.76 Å) | | Cite: | Crystal structure of Salmonella typhi outer membrane phospholipase (OMPLA) dimer with bound calcium
To Be Published
|
|
7F3U
 | | Cryo-EM structure of human TMEM120A in the CoASH-free state | | Descriptor: | Transmembrane protein 120A | | Authors: | Rong, Y, Gao, Y.W, Song, D.F, Zhao, Y, Liu, Z.F. | | Deposit date: | 2021-06-17 | | Release date: | 2021-06-30 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells.
Elife, 10, 2021
|
|
7F3T
 | |
7F4G
 | | Structure of RPAP2-bound RNA polymerase II | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Chen, X, Qi, Y, Wang, X, Li, J, Zhao, D, Xu, Y. | | Deposit date: | 2021-06-18 | | Release date: | 2021-07-07 | | Last modified: | 2022-07-20 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex.
Cell Rep, 39, 2022
|
|
7EV7
 | | Bovine heart cytochrome c oxidase in the carbon monoxide-bound fully reduced state at a 50 K | | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | | Authors: | Shimada, A, Yoshikawa, S, Tsukihara, T. | | Deposit date: | 2021-05-20 | | Release date: | 2021-07-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of CO-bound fully reduced state of bovine heart cytochrome c oxidase
To Be Published
|
|
2IJG
 | | Crystal Structure of cryptochrome 3 from Arabidopsis thaliana | | Descriptor: | 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, Cryptochrome DASH, chloroplast/mitochondrial, ... | | Authors: | Huang, Y, Deisenhofer, J. | | Deposit date: | 2006-09-29 | | Release date: | 2006-11-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity
Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2IXK
 | |
7EV9
 | | cryoEM structure of particulate methane monooxygenase associated with Cu(I) | | Descriptor: | Ammonia monooxygenase/methane monooxygenase, subunit C family protein, COPPER (I) ION, ... | | Authors: | Chang, W.H, Lin, H.H, Tsai, I.K, Huang, S.H, Chung, S.C, Tu, I.P, Yu, S.F, Chan, S.I. | | Deposit date: | 2021-05-20 | | Release date: | 2021-07-21 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Copper Centers in the Cryo-EM Structure of Particulate Methane Monooxygenase Reveal the Catalytic Machinery of Methane Oxidation.
J.Am.Chem.Soc., 143, 2021
|
|
2J2P
 | | L-ficolin complexed to N-acetyl-cystein (150mM) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FICOLIN-2, ... | | Authors: | Garlatti, V, Gaboriaud, C. | | Deposit date: | 2006-08-17 | | Release date: | 2007-01-23 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins.
Embo J., 26, 2007
|
|
2IVE
 | | Structure of protoporphyrinogen oxidase from Myxococcus xanthus | | Descriptor: | (3S)-3-[(2S,3S,4R)-3,4-DIMETHYLTETRAHYDROFURAN-2-YL]BUTYL LAURATE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | Authors: | Corradi, H.R, Corrigall, A.V, Boix, E, Mohan, C.G, Sturrock, E.D, Meissner, P.N, Acharya, K.R. | | Deposit date: | 2006-06-13 | | Release date: | 2006-10-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structure of Protoporphyrinogen Oxidase from Myxococcus Xanthus and its Complex with the Inhibitor Acifluorfen.
J.Biol.Chem., 281, 2006
|
|
