7ETW
Cryo-EM structure of Scap/Insig complex in the present of digitonin.
Summary for 7ETW
Entry DOI | 10.2210/pdb7etw/pdb |
EMDB information | 31303 |
Descriptor | Insulin-induced gene 2 protein, Sterol regulatory element-binding protein cleavage-activating protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | sterol sensing, srebp, scap, insig, cholestrol, digitonin, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 111954.84 |
Authors | |
Primary citation | Yan, R.,Cao, P.,Song, W.,Li, Y.,Wang, T.,Qian, H.,Yan, C.,Yan, N. Structural basis for sterol sensing by Scap and Insig Cell Rep, 35:109299-, 2021 Cited by DOI: 10.1016/j.celrep.2021.109299PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.1 Å) |
Structure validation
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