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3QIN
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BU of 3qin by Molmil
Crystal Structure of HIV-1 RNase H p15 with engineered E. coli loop and pyrimidinol carboxylic acid inhibitor
Descriptor: 2-(3-bromo-4-methoxybenzyl)-5,6-dihydroxypyrimidine-4-carboxylic acid, Fusion protein of HIV-1 RNase H p15 with engineered E. coli loop, MANGANESE (II) ION, ...
Authors:Lansdon, E.B, Kirschberg, T.A.
Deposit date:2011-01-27
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6967 Å)
Cite:Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors.
Antimicrob.Agents Chemother., 55, 2011
1HT4
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BU of 1ht4 by Molmil
SOLUTION STRUCTURE OF A BISTRAND ABASIC SITE LESION STAGGERED IN A 3'-ORIENTATION.
Descriptor: 5'-D(*CP*GP*CP*AP*TP*GP*(3DR)P*GP*TP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*AP*CP*AP*(3DR)P*AP*TP*GP*CP*G)-3'
Authors:Lin, Z, de los Santos, C.
Deposit date:2000-12-28
Release date:2001-05-02
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR characterization of clustered bistrand abasic site lesions: effect of orientation on their solution structure.
J.Mol.Biol., 308, 2001
3WQO
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BU of 3wqo by Molmil
Crystal structure of D-tagatose 3-epimerase-like protein
Descriptor: MANGANESE (II) ION, Uncharacterized protein MJ1311
Authors:Uechi, K, Takata, G, Yoneda, K, Ohshima, T, Sakuraba, H.
Deposit date:2014-01-28
Release date:2014-07-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structure of D-tagatose 3-epimerase-like protein from Methanocaldococcus jannaschii
Acta Crystallogr.,Sect.F, 70, 2014
5B7I
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BU of 5b7i by Molmil
Cas3-AcrF3 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST, ...
Authors:Wang, X, Zhu, Y.
Deposit date:2016-06-07
Release date:2016-07-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of Cas3 inhibition by the bacteriophage protein AcrF3
Nat.Struct.Mol.Biol., 23, 2016
3OKG
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BU of 3okg by Molmil
Crystal structure of HsdS subunit from Thermoanaerobacter tengcongensis
Descriptor: Restriction endonuclease S subunits, SULFATE ION
Authors:Liang, D, Gao, P, Tang, Q, An, X, Yan, X.
Deposit date:2010-08-24
Release date:2011-05-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of HsdS subunit from Thermoanaerobacter tengcongensis sheds lights on mechanism of dynamic opening and closing of type I methyltransferase
Plos One, 6, 2011
1V65
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BU of 1v65 by Molmil
Solution structure of the Kruppel-associated box (KRAB) domain
Descriptor: RIKEN cDNA 2610044O15
Authors:Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-11-27
Release date:2004-06-01
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the Kruppel-associated box (KRAB) domain
To be Published
1K2K
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BU of 1k2k by Molmil
NMR MINIMIZED AVERAGE STRUCTURE OF d(CGTACG)2
Descriptor: 5'-D(*CP*GP*TP*AP*CP*G)-3'
Authors:Lam, S.L, Ip, L.N.
Deposit date:2001-09-28
Release date:2002-04-10
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Low temperature solution structures and base pair stacking of double helical d(CGTACG)(2).
J.Biomol.Struct.Dyn., 19, 2002
2A93
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BU of 2a93 by Molmil
NMR SOLUTION STRUCTURE OF THE C-MYC-MAX HETERODIMERIC LEUCINE ZIPPER, 40 STRUCTURES
Descriptor: C-MYC-MAX HETERODIMERIC LEUCINE ZIPPER
Authors:Lavigne, P, Crump, M.P, Gagne, S.M, Hodges, R.S, Kay, C.M, Sykes, B.D.
Deposit date:1998-06-09
Release date:1999-01-27
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Insights into the mechanism of heterodimerization from the 1H-NMR solution structure of the c-Myc-Max heterodimeric leucine zipper.
J.Mol.Biol., 281, 1998
1J7D
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BU of 1j7d by Molmil
Crystal Structure of hMms2-hUbc13
Descriptor: MMS2, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA
Authors:Moraes, T.F, Edwards, R.A, McKenna, S, Pashushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J.
Deposit date:2001-05-16
Release date:2001-08-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.
Nat.Struct.Biol., 8, 2001
1T7B
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BU of 1t7b by Molmil
Crystal structure of mutant Lys8Gln of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch
Descriptor: Alpha-like neurotoxin BmK-I
Authors:Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C.
Deposit date:2004-05-09
Release date:2004-09-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins
J.Mol.Biol., 341, 2004
2REU
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BU of 2reu by Molmil
Crystal Structure of the C-terminal of Sau3AI fragment
Descriptor: MAGNESIUM ION, Type II restriction enzyme Sau3AI
Authors:Hu, X, Yu, F, Xu, C, He, J.
Deposit date:2007-09-27
Release date:2008-09-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and function of C-terminal Sau3AI domain
Biochim.Biophys.Acta, 1794, 2009
6EG3
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BU of 6eg3 by Molmil
Crystal structure of human BRM in complex with compound 15
Descriptor: 3-[(4-{[(2-chloropyridin-4-yl)carbamoyl]amino}pyridin-2-yl)ethynyl]benzoic acid, ETHANOL, Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2
Authors:Zhu, X, Kulathila, R, Hu, T, Xie, X.
Deposit date:2018-08-17
Release date:2018-10-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers.
J. Med. Chem., 61, 2018
6EG2
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BU of 6eg2 by Molmil
Crystal structure of human BRM in complex with compound 16
Descriptor: ISOPROPYL ALCOHOL, Maltose/maltodextrin-binding periplasmic protein,Probable global transcription activator SNF2L2, N-(5-amino-2-chloropyridin-4-yl)-N'-(4-bromo-3-{[3-(hydroxymethyl)phenyl]ethynyl}-1,2-thiazol-5-yl)urea
Authors:Zhu, X, Kulathila, R, Hu, T, Xie, X.
Deposit date:2018-08-17
Release date:2018-10-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers.
J. Med. Chem., 61, 2018
3HI8
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BU of 3hi8 by Molmil
Crystal structure of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii
Descriptor: Proliferating cell nuclear antigen PcnA
Authors:Morgunova, E, Gray, F.C, MacNeill, S.A, Ladenstein, R.
Deposit date:2009-05-19
Release date:2009-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.202 Å)
Cite:Structural insights into the adaptation of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii to a high-salt environment.
Acta Crystallogr.,Sect.D, 65, 2009
1WLJ
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BU of 1wlj by Molmil
human ISG20
Descriptor: ACETATE ION, MANGANESE (II) ION, URIDINE-5'-MONOPHOSPHATE, ...
Authors:Horio, T, Murai, M, Inoue, T, Hamasaki, T, Tanaka, T, Ohgi, T.
Deposit date:2004-06-28
Release date:2004-12-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human ISG20, an interferon-induced antiviral ribonuclease
Febs Lett., 577, 2004
6J90
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BU of 6j90 by Molmil
Crystal Structure of GyraseB N-Terminal Domain complex with ATP from Salmonella Typhi at 2.2A Resolution
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Kaur, G, Sachdeva, E, Tiwari, P, Gupta, D, Ethayathulla, A.S, Kaur, P.
Deposit date:2019-01-21
Release date:2020-01-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of GyraseB N-Terminal Domain complex with ATP from Salmonella Typhi at 2.2A Resolution
To Be Published
1THC
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BU of 1thc by Molmil
CRYSTAL STRUCTURE DETERMINATION AT 2.3A OF HUMAN TRANSTHYRETIN-3',5'-DIBROMO-2',4,4',6-TETRA-HYDROXYAURONE COMPLEX
Descriptor: 3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE, TRANSTHYRETIN
Authors:Ciszak, E, Cody, V, Luft, J.R.
Deposit date:1992-04-20
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure determination at 2.3-A resolution of human transthyretin-3',5'-dibromo-2',4,4',6-tetrahydroxyaurone complex.
Proc.Natl.Acad.Sci.USA, 89, 1992
4JPO
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BU of 4jpo by Molmil
5A resolution structure of Proteasome Assembly Chaperone Hsm3 in complex with a C-terminal fragment of Rpt1
Descriptor: 26S protease regulatory subunit 7 homolog, DNA mismatch repair protein HSM3
Authors:Lovell, S, Battaile, K.P, Singh, R, Roelofs, J.
Deposit date:2013-03-19
Release date:2013-04-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (5 Å)
Cite:Reconfiguration of the proteasome during chaperone-mediated assembly.
Nature, 497, 2013
4JQF
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BU of 4jqf by Molmil
Structure of the C-terminal domain of human telomeric Stn1
Descriptor: CST complex subunit STN1
Authors:Bryan, C.F, Rice, C.T, Harkisheimer, M, Schultz, D, Skordalakes, E.
Deposit date:2013-03-20
Release date:2013-06-05
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the human telomeric stn1-ten1 capping complex.
Plos One, 8, 2013
1VZK
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BU of 1vzk by Molmil
A Thiophene Based Diamidine Forms a "Super" AT Binding Minor Groove Agent
Descriptor: 2-(5-{4-[AMINO(IMINO)METHYL]PHENYL}-2-THIENYL)-1H-BENZIMIDAZOLE-6- CARBOXIMIDAMIDE DIHYDROCHLORIDE, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP *CP*G)-3', MAGNESIUM ION
Authors:Mallena, S, Lee, M.P.H, Bailly, C, Neidle, S, Kumar, A, Boykin, D.W, Wilson, W.D.
Deposit date:2004-05-20
Release date:2004-10-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Thiophene-Based Diamidine Forms a "Super" at Binding Minor Groove Agent
J.Am.Chem.Soc., 142, 2004
1TYR
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BU of 1tyr by Molmil
TRANSTHYRETIN COMPLEX WITH RETINOIC ACID
Descriptor: (9cis)-retinoic acid, TRANSTHYRETIN
Authors:Zanotti, G, D'Acunto, M.R, Malpeli, G, Folli, C, Berni, R.
Deposit date:1995-05-12
Release date:1995-09-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the transthyretin--retinoic-acid complex
Eur.J.Biochem., 234, 1995
5D1Y
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BU of 5d1y by Molmil
Low resolution crystal structure of human ribonucleotide reductase alpha6 hexamer in complex with dATP
Descriptor: Ribonucleoside-diphosphate reductase large subunit
Authors:Ando, N, Li, H, Brignole, E.J, Thompson, S, McLaughlin, M.I, Page, J, Asturias, F, Stubbe, J, Drennan, C.L.
Deposit date:2015-08-04
Release date:2016-01-20
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (9.005 Å)
Cite:Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer.
Biochemistry, 55, 2016
1T7E
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BU of 1t7e by Molmil
Crystal structure of mutant Pro9Ser of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch
Descriptor: Alpha-like neurotoxin BmK-I, PHOSPHATE ION
Authors:Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C.
Deposit date:2004-05-09
Release date:2004-09-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins
J.Mol.Biol., 341, 2004
1FNN
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BU of 1fnn by Molmil
CRYSTAL STRUCTURE OF CDC6P FROM PYROBACULUM AEROPHILUM
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CELL DIVISION CONTROL PROTEIN 6, MAGNESIUM ION
Authors:Liu, J, Smith, C.L, DeRyckere, D, DeAngelis, K, Martin, G.S, Berger, J.M.
Deposit date:2000-08-22
Release date:2000-10-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control.
Mol.Cell, 6, 2000
5DSA
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BU of 5dsa by Molmil
Crystal structure of Holliday junctions stabilized by 5-methylcytosine in GCC junction core
Descriptor: 5'-D(*CP*CP*GP*GP*CP*GP*5CMP*CP*GP*G)-3', CALCIUM ION
Authors:Vander Zanden, C.M, Ho, P.S.
Deposit date:2015-09-17
Release date:2016-09-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6896 Å)
Cite:Effect of Hydroxymethylcytosine on the Structure and Stability of Holliday Junctions.
Biochemistry, 55, 2016

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