5D1Y

Low resolution crystal structure of human ribonucleotide reductase alpha6 hexamer in complex with dATP

Summary for 5D1Y

Entry DOI	10.2210/pdb5d1y/pdb
Descriptor	Ribonucleoside-diphosphate reductase large subunit (1 entity in total)
Functional Keywords	deoxyribonucleotide, oligomerization, atp cone, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	184700.78
Authors	Ando, N.,Li, H.,Brignole, E.J.,Thompson, S.,McLaughlin, M.I.,Page, J.,Asturias, F.,Stubbe, J.,Drennan, C.L. (deposition date: 2015-08-04, release date: 2016-01-20, Last modification date: 2023-09-27)
Primary citation	Ando, N.,Li, H.,Brignole, E.J.,Thompson, S.,McLaughlin, M.I.,Page, J.E.,Asturias, F.J.,Stubbe, J.,Drennan, C.L. Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer. Biochemistry, 55:373-381, 2016 Cited by PubMed: 26727048 DOI: 10.1021/acs.biochem.5b01207 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (9.005 Å)

Structure validation