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1IQ1
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BU of 1iq1 by Molmil
CRYSTAL STRUCTURE OF THE IMPORTIN-ALPHA(44-54)-IMPORTIN-ALPHA(70-529) COMPLEX
Descriptor: IMPORTIN ALPHA-2 SUBUNIT
Authors:Catimel, B, Teh, T, Fontes, M.R.M, Jennings, I.G, Kobe, B.
Deposit date:2001-05-28
Release date:2001-11-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Biophysical characterization of interactions involving importin-alpha during nuclear import.
J.Biol.Chem., 276, 2001
4BQK
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BU of 4bqk by Molmil
rice importin_alpha : VirD2NLS complex
Descriptor: DI(HYDROXYETHYL)ETHER, IMPORTIN SUBUNIT ALPHA-1A, T-DNA BORDER ENDONUCLEASE VIRD2
Authors:Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
Deposit date:2013-05-31
Release date:2014-02-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium Vird2 with Rice Importin-Alpha
Mol.Plant, 7, 2014
4BPL
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BU of 4bpl by Molmil
rice importin_alpha in complex with nucleoplasmin NLS
Descriptor: IMPORTIN SUBUNIT ALPHA-1A, NUCLEOPLASMIN NLS
Authors:Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
Deposit date:2013-05-27
Release date:2014-02-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium Vird2 with Rice Importin-Alpha
Mol.Plant, 7, 2014
8HKW
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BU of 8hkw by Molmil
Crystal structure of importin-alpha3 bound to the 53BP1 nuclear localization signal
Descriptor: Importin subunit alpha-3, Peptide from TP53-binding protein 1
Authors:Matsuura, Y.
Deposit date:2022-11-28
Release date:2022-12-21
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic data of an importin-alpha 3 dimer in which the two protomers are bridged by a bipartite nuclear localization signal.
Data Brief, 47, 2023
8HE3
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BU of 8he3 by Molmil
Crystal structure of importin-alpha1 bound to the HIF-1alpha nuclear localization signal (delta 724-751)
Descriptor: Hypoxia-inducible factor 1-alpha, Importin subunit alpha-1, SULFATE ION
Authors:Matsuura, Y.
Deposit date:2022-11-07
Release date:2023-02-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of importin-alpha bound to the wild-type and an internal deletion mutant of the bipartite nuclear localization signal of HIF-1 alpha.
Biochem.Biophys.Res.Commun., 652, 2023
8HE0
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BU of 8he0 by Molmil
Crystal structure of importin-alpha1 bound to the HIF-1alpha nuclear localization signal (wild-type)
Descriptor: Hypoxia-inducible factor 1-alpha, Importin subunit alpha-1
Authors:Matsuura, Y.
Deposit date:2022-11-07
Release date:2023-02-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of importin-alpha bound to the wild-type and an internal deletion mutant of the bipartite nuclear localization signal of HIF-1 alpha.
Biochem.Biophys.Res.Commun., 652, 2023
7N8J
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BU of 7n8j by Molmil
Human importin alpha 1 in complex with Bimax2 peptide
Descriptor: BIMAX2, Importin subunit alpha-1
Authors:Donnelly, C.M, Cross, E.M, Tsimbalyuk, S, Forwood, J.K.
Deposit date:2021-06-15
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Human importin alpha 1:Bimax2 peptide complex
To Be Published
1IAL
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BU of 1ial by Molmil
IMPORTIN ALPHA, MOUSE
Descriptor: IMPORTIN ALPHA
Authors:Kobe, B.
Deposit date:1999-01-12
Release date:1999-06-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alpha.
Nat.Struct.Biol., 6, 1999
1I7X
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BU of 1i7x by Molmil
BETA-CATENIN/E-CADHERIN COMPLEX
Descriptor: BETA-CATENIN, EPITHELIAL-CADHERIN
Authors:Huber, A.H, Weis, W.I.
Deposit date:2001-03-10
Release date:2001-05-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin.
Cell(Cambridge,Mass.), 105, 2001
7N9H
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BU of 7n9h by Molmil
Structure of the mammalian importin a1 bound to the TDP-43 NLS
Descriptor: Importin subunit alpha-1, TAR DNA-binding protein 43
Authors:Doll, S.G, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta.
Cell Rep, 39, 2022
6BVV
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BU of 6bvv by Molmil
Nipah virus W protein C-terminus in complex with Importin alpha 3
Descriptor: Importin subunit alpha-3, Protein W
Authors:Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-13
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
8GCN
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BU of 8gcn by Molmil
CRYO-EM STRUCTURE OF IMPORTIN ALPHA1/BETA HETERODIMER
Descriptor: Importin subunit alpha-1, Importin subunit beta-1
Authors:Ko, Y, Cingolani, G.
Deposit date:2023-03-02
Release date:2024-03-06
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core.
Sci Adv, 10, 2024
1I7W
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BU of 1i7w by Molmil
BETA-CATENIN/PHOSPHORYLATED E-CADHERIN COMPLEX
Descriptor: BETA-CATENIN, CHLORIDE ION, EPITHELIAL-CADHERIN, ...
Authors:Huber, A.H, Weis, W.I.
Deposit date:2001-03-10
Release date:2001-05-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin.
Cell(Cambridge,Mass.), 105, 2001
4B18
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BU of 4b18 by Molmil
The crystal structure of human Importin alpha 5 with TERT NLS peptide
Descriptor: IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE TRANSCRIPTASE
Authors:Kim, K.L, Yoo, J.H, Cho, H.S.
Deposit date:2012-07-08
Release date:2013-09-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Akt-Mediated Phosphorylation Increases the Binding Affinity of Htert for Importin Alpha to Promote Nuclear Translocation.
J.Cell.Sci., 128, 2015
8G4J
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BU of 8g4j by Molmil
Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in cargo-free state
Descriptor: Importin subunit alpha
Authors:Hawker, J.E, Roby, J.A, Stewart, M, Forwood, J.K.
Deposit date:2023-02-09
Release date:2023-02-22
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in cargo-free state
To Be Published
8GAI
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BU of 8gai by Molmil
Cavia porcellus (guinea pig) importin-alpha 1 in complex with Bimax2 peptide
Descriptor: Bimax2, Importin subunit alpha
Authors:Hawker, J.E, Forwood, J.K, Donnelly, C.M, Stewart, M.
Deposit date:2023-02-22
Release date:2023-04-05
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in complex with bimax2 peptide
To Be Published
8GSJ
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BU of 8gsj by Molmil
APC-Asef tripeptide inhibitor
Descriptor: (1R,2S)-2-phenylcyclopropanamine, 2-methylsulfanylpyrimidine-4-carbaldehyde, Adenomatous polyposis coli protein, ...
Authors:Zhang, J, Wang, X.F, Song, K.
Deposit date:2022-09-06
Release date:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:APC-Asef tripeptide inhibitor
To Be Published
6BVT
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BU of 6bvt by Molmil
Importin alpha 1 in cargo free state
Descriptor: Importin subunit alpha-1
Authors:Smith, K.M, Tsimablyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-13
Release date:2018-07-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BW1
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BU of 6bw1 by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 1
Descriptor: Importin subunit alpha-1, Protein W
Authors:Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
7NSC
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BU of 7nsc by Molmil
Substrate receptor scaffolding module of human CTLH E3 ubiquitin ligase
Descriptor: Glucose-induced degradation protein 4 homolog, Glucose-induced degradation protein 8 homolog, Isoform 2 of Armadillo repeat-containing protein 8, ...
Authors:Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A.
Deposit date:2021-03-05
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
6BW0
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BU of 6bw0 by Molmil
Nipah virus W protein C-terminus in complex with Importin alpha 1
Descriptor: Importin subunit alpha-1, Protein W
Authors:Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BWB
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BU of 6bwb by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3
Descriptor: Importin subunit alpha-3, Protein W
Authors:Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
3ZIO
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BU of 3zio by Molmil
minor-site specific NLS (A28)
Descriptor: A28NLS, IMPORTIN SUBUNIT ALPHA-2
Authors:Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
Deposit date:2013-01-10
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
6BW9
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BU of 6bw9 by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 1
Descriptor: Importin subunit alpha-3, Protein W
Authors:Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
8G8Q
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BU of 8g8q by Molmil
RelB NLS in complex with Importin alpha 2
Descriptor: Importin subunit alpha-1, bacterial peptide, monopartite p52 NLS
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:p52 monopartite NLS in complex with Importin alpha 2
To Be Published

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