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7A5K
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BU of 7a5k by Molmil
Structure of the human mitoribosome in the post translocation state bound to mtEF-G1
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ...
Authors:Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V.
Deposit date:2020-08-21
Release date:2020-12-23
Last modified:2022-12-07
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Elongational stalling activates mitoribosome-associated quality control.
Science, 370, 2020
6ZSA
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BU of 6zsa by Molmil
Human mitochondrial ribosome bound to mRNA, A-site tRNA and P-site tRNA
Descriptor: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ...
Authors:Aibara, S, Singh, V, Modelska, A, Amunts, A.
Deposit date:2020-07-15
Release date:2020-10-21
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of mitochondrial translation.
Elife, 9, 2020
6ZM5
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BU of 6zm5 by Molmil
Human mitochondrial ribosome in complex with OXA1L, mRNA, A/A tRNA, P/P tRNA and nascent polypeptide
Descriptor: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ...
Authors:Itoh, Y, Andrell, J, Amunts, A.
Deposit date:2020-07-01
Release date:2021-01-13
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Mechanism of membrane-tethered mitochondrial protein synthesis.
Science, 371, 2021
6ZSE
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BU of 6zse by Molmil
Human mitochondrial ribosome in complex with mRNA, A/P-tRNA and P/E-tRNA
Descriptor: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ...
Authors:Aibara, S, Singh, V, Modelska, A, Amunts, A.
Deposit date:2020-07-15
Release date:2020-09-16
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural basis of mitochondrial translation.
Elife, 9, 2020
6ZSB
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BU of 6zsb by Molmil
Human mitochondrial ribosome in complex with mRNA and P-site tRNA
Descriptor: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ...
Authors:Aibara, S, Singh, V, Modelska, A, Amunts, A.
Deposit date:2020-07-15
Release date:2020-09-16
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural basis of mitochondrial translation.
Elife, 9, 2020
1XP8
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BU of 1xp8 by Molmil
Deinococcus radiodurans RecA in complex with ATP-gamma-S
Descriptor: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, RecA protein
Authors:Bell, C.E, Rajan, R.
Deposit date:2004-10-08
Release date:2004-12-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of RecA from Deinococcus radiodurans: insights into the structural basis of extreme radioresistance.
J.Mol.Biol., 344, 2004
4B8X
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BU of 4b8x by Molmil
Near atomic resolution crystal structure of Sco5413, a MarR family transcriptional regulator from Streptomyces coelicolor
Descriptor: CHLORIDE ION, POSSIBLE MARR-TRANSCRIPTIONAL REGULATOR
Authors:Holley, T.A, Stevenson, C.E.M, Bibb, M.J, Lawson, D.M.
Deposit date:2012-08-31
Release date:2012-10-17
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:High Resolution Crystal Structure of Sco5413, a Widespread Actinomycete Marr Family Transcriptional Regulator of Unknown Function.
Proteins, 81, 2013
4WT8
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BU of 4wt8 by Molmil
Crystal Structure of bactobolin A bound to 70S ribosome-tRNA complex
Descriptor: 23S rRNA (2899-MER), 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Amunts, A, Fiedorczuk, K, Ramakrishnan, V.
Deposit date:2014-10-29
Release date:2015-01-21
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics.
J.Mol.Biol., 427, 2015
7A5H
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BU of 7a5h by Molmil
Structure of the split human mitoribosomal large subunit with rescue factors mtRF-R and MTRES1
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V.
Deposit date:2020-08-21
Release date:2020-12-23
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Elongational stalling activates mitoribosome-associated quality control.
Science, 370, 2020
8OVX
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BU of 8ovx by Molmil
Cryo-EM structure of yeast CENP-OPQU+ bound to the CENP-A N-terminus
Descriptor: Inner kinetochore subunit AME1, Inner kinetochore subunit CTF19, Inner kinetochore subunit MCM21, ...
Authors:Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S.
Deposit date:2023-04-26
Release date:2023-08-09
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
6K5S
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BU of 6k5s by Molmil
Crystal structure of the Helical domain of S. pombe Tbf1
Descriptor: Telomeric DNA-binding factor trf1
Authors:Zhou, Y.Z, Wang, N.N, Zhao, Y.C, Zeng, Z.X.
Deposit date:2019-05-31
Release date:2020-06-03
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:Crystal structure of the Helical domain of S. pombe Tbf1
To Be Published
2BE2
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BU of 2be2 by Molmil
Crystal structure of HIV-1 reverse transcriptase (RT) in complex with R221239
Descriptor: 4-(3,5-DIMETHYLPHENOXY)-5-(FURAN-2-YLMETHYLSULFANYLMETHYL)-3-IODO-6-METHYLPYRIDIN-2(1H)-ONE, GLYCEROL, MANGANESE (II) ION, ...
Authors:Himmel, D.M, Das, K, Clark Jr, A.D, Hughes, S.H, Benjahad, A, Oumouch, S, Guillemont, J, Coupa, S, Poncelet, A, Csoka, I, Meyer, C, Andries, K, Nguyen, C.H, Grierson, D.S, Arnold, E.
Deposit date:2005-10-21
Release date:2005-12-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains.
J.Med.Chem., 48, 2005
2HDE
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BU of 2hde by Molmil
Solution Structure of Human SAP18
Descriptor: Histone deacetylase complex subunit SAP18
Authors:McCallum, S.A, Yin, J.P, Pan, B, Fairbrother, W.J.
Deposit date:2006-06-20
Release date:2007-04-24
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of SAP18: a ubiquitin fold in histone deacetylase complex assembly.
Biochemistry, 45, 2006
2B5J
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BU of 2b5j by Molmil
Crystal structure of HIV-1 reverse transcriptase (RT) in complex with JANSSEN-R165481
Descriptor: (2E)-3-{3-[(5-ETHYL-3-IODO-6-METHYL-2-OXO-1,2-DIHYDROPYRIDIN-4-YL)OXY]PHENYL}ACRYLONITRILE, MANGANESE (II) ION, Reverse transcriptase P51 SUBUNIT, ...
Authors:Himmel, D.H, Das, K, Clark Jr, A.D, Hughes, S.H, Benjahad, A, Oumouch, S, Guillemont, J, Coupa, S, Poncelet, A, Csoka, I, Meyer, C, Andries, K, Mguyen, C.H, Grierson, D.S, Arnold, E.
Deposit date:2005-09-28
Release date:2005-12-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains.
J.Med.Chem., 48, 2005
5B32
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BU of 5b32 by Molmil
The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.3.
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
Authors:Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H.
Deposit date:2016-02-08
Release date:2016-08-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A.
Open Biology, 6, 2016
7Y56
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BU of 7y56 by Molmil
Crystal structure of NS1 nuclease domain in P41212 space group
Descriptor: GLYCEROL, NS1 protein
Authors:Zhang, X.Y, Gan, J.H.
Deposit date:2022-06-16
Release date:2023-07-05
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein.
Comput Struct Biotechnol J, 20, 2022
7Y57
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BU of 7y57 by Molmil
Crystal structure of NS1 nuclease domain in P21 space group
Descriptor: NS1 protein, PHOSPHATE ION
Authors:Zhang, X.Y, Gan, J.H.
Deposit date:2022-06-16
Release date:2023-07-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.183 Å)
Cite:Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein.
Comput Struct Biotechnol J, 20, 2022
485D
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BU of 485d by Molmil
A SULFATE POCKET FORMED BY THREE GOU PAIRS IN THE STRUCTURE OF A NONAMERIC RNA
Descriptor: RNA/DNA(5'-R(*CP*GP*UP*GP*AP*UP*CP*GP)-D(*C)-3'), SULFATE ION
Authors:Masquida, B, Sauter, C, Westhof, E.
Deposit date:1999-08-13
Release date:1999-12-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:A sulfate pocket formed by three GoU pairs in the 0.97 A resolution X-ray structure of a nonameric RNA.
RNA, 5, 1999
6TUU
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BU of 6tuu by Molmil
Leishmania infantum Rad51 surrogate LiRadA10 in complex with 5,6,7,8-tetrahydro-2-naphthoic acid
Descriptor: 5,6,7,8-tetrahydronaphthalene-2-carboxylic acid, CHLORIDE ION, DNA repair and recombination protein RadA, ...
Authors:Pantelejevs, T, Hyvonen, M.
Deposit date:2020-01-08
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Development of dedicated crystallographic systems for structure-guided drug discovery
To Be Published
3SZ5
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BU of 3sz5 by Molmil
Crystal Structure of LHK-Exo in complex with 5-phosphorylated oligothymidine (dT)4
Descriptor: 5'-D(P*TP*TP*TP*T)-3', Exonuclease, MAGNESIUM ION
Authors:Yang, W, Chen, W.Y, Wang, H, Zhang, Q, Zhou, W, Bartlam, M, Watt, R.M, Rao, Z.
Deposit date:2011-07-18
Release date:2012-02-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis.
Nucleic Acids Res., 39, 2011
5B31
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BU of 5b31 by Molmil
The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.1.
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
Authors:Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H.
Deposit date:2016-02-08
Release date:2016-08-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A.
Open Biology, 6, 2016
2WAL
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BU of 2wal by Molmil
Crystal Structure of human GADD45gamma
Descriptor: GROWTH ARREST AND DNA-DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA, MALONIC ACID
Authors:Bhattacharya, S, Mueller, J.J, Roske, Y, Turnbull, A.P, Quedenau, C, Goetz, F, Buessow, K, Heinemann, U.
Deposit date:2009-02-09
Release date:2009-03-03
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of Human Gadd45Gamma
To be Published
2BAN
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BU of 2ban by Molmil
Crystal structure of HIV-1 reverse transcriptase (RT) in complex with JANSSEN-R157208
Descriptor: 5-ETHYL-3-[(2-METHOXYETHYL)METHYLAMINO]-6-METHYL-4-(3-METHYLBENZYL)PYRIDIN-2(1H)-ONE, MANGANESE (II) ION, Reverse transcriptase P51 subunit, ...
Authors:Das, K, Arnold, E.
Deposit date:2005-10-14
Release date:2005-12-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains.
J.Med.Chem., 48, 2005
6GYG
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BU of 6gyg by Molmil
X-ray structure of the apo form of the establishement gene regulator Reg576 of the G+ plasmid p576
Descriptor: Transcription regulator Reg576
Authors:Crespo, I, Meijer, W.J.J, Boer, D.R.
Deposit date:2018-06-29
Release date:2018-10-17
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Novel regulatory mechanism of establishment genes of conjugative plasmids.
Nucleic Acids Res., 46, 2018
6J8V
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BU of 6j8v by Molmil
Structure of MOEN5-SSO7D fusion protein in complex with ligand 2
Descriptor: FARNESYL, MoeN5,DNA-binding protein 7d
Authors:Ko, T.P, Zhang, L.L, Chen, C.C, Guo, R.T.
Deposit date:2019-01-21
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism.
Biochem. Biophys. Res. Commun., 511, 2019

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