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6R8N
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BU of 6r8n by Molmil
STRUCTURE DETERMINATION OF THE TETRAHEDRAL AMINOPEPTIDASE TET2 FROM P. HORIKOSHII BY USE OF COMBINED SOLID-STATE NMR, SOLUTION-STATE NMR AND EM DATA 4.1 A, FOLLOWED BY REAL_SPACE_REFINEMENT AT 4.1 A
Descriptor: Tetrahedral aminopeptidase, ZINC ION
Authors:Colletier, J.-P, Gauto, D, Estrozi, L, Favier, A, Effantin, G, Schoehn, G, Boisbouvier, J, Schanda, P.
Deposit date:2019-04-02
Release date:2019-08-14
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (4.1 Å), SOLUTION NMR
Cite:Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex.
Nat Commun, 10, 2019
6R92
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BU of 6r92 by Molmil
Cryo-EM structure of NCP-THF2(+1)-UV-DDB class B
Descriptor: DNA damage-binding protein 1,DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ...
Authors:Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H.
Deposit date:2019-04-02
Release date:2019-06-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
6R9Z
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BU of 6r9z by Molmil
3D NMR solution structure of ligand peptide (Ac)EVNPPVP of Pro-Pro endopeptidase-1
Descriptor: ACE-GLU-VAL-ASN-PRO-PRO-VAL-PRO-NH2
Authors:Diaz, D.
Deposit date:2019-04-04
Release date:2019-06-19
Last modified:2019-08-07
Method:SOLUTION NMR
Cite:Molecular determinants of the mechanism and substrate specificity ofClostridium difficileproline-proline endopeptidase-1.
J.Biol.Chem., 294, 2019
6UVS
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BU of 6uvs by Molmil
Human Connexin-26 (Low pH open conformation)
Descriptor: Gap junction beta-2 protein
Authors:Khan, A.K, Jagielnicki, M, Purdy, M.D, Yeager, M.
Deposit date:2019-11-04
Release date:2020-04-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:A Steric "Ball-and-Chain" Mechanism for pH-Mediated Regulation of Gap Junction Channels.
Cell Rep, 31, 2020
6R93
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BU of 6r93 by Molmil
Cryo-EM structure of NCP-6-4PP
Descriptor: Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ...
Authors:Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H.
Deposit date:2019-04-02
Release date:2019-06-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
6QTF
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BU of 6qtf by Molmil
Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring B, major conformer
Descriptor: DCY-LEU-GLY-ALA-THR
Authors:Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B.
Deposit date:2019-02-25
Release date:2019-09-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B.
J.Org.Chem., 84, 2019
6QYU
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BU of 6qyu by Molmil
Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring A
Descriptor: PHE-DHA-DAL-LEU-DHA-LEU-CYS-ALA
Authors:Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B.
Deposit date:2019-03-09
Release date:2019-09-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B.
J.Org.Chem., 84, 2019
6QM1
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BU of 6qm1 by Molmil
Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Nisin Ring B (Lan8,11) analogue
Descriptor: DAL-PRO-GLY-CYS-LYS
Authors:Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B.
Deposit date:2019-02-01
Release date:2019-09-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B.
J.Org.Chem., 84, 2019
6R1V
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BU of 6r1v by Molmil
Solution structure of sortase A from S. aureus in complex with 2-(aminomethyl)-3-hydroxy-4H-pyran-4-one based prodrug
Descriptor: 6-(hydroxymethyl)-3-oxidanyl-2-(thiophen-3-ylmethyl)pyran-4-one, Sortase A
Authors:Jaudzems, K, Leonchiks, A.
Deposit date:2019-03-15
Release date:2020-01-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Targeting Bacterial Sortase A with Covalent Inhibitors: 27 New Starting Points for Structure-Based Hit-to-Lead Optimization.
Acs Infect Dis., 6, 2020
6QYR
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BU of 6qyr by Molmil
Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring B, minor conformer
Descriptor: DAL-LEU-GLY-CYS-THR
Authors:Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B.
Deposit date:2019-03-09
Release date:2019-09-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B.
J.Org.Chem., 84, 2019
6R95
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BU of 6r95 by Molmil
The solution NMR structure of cis-dicarba-brevinin-1BYa in 33% trifluoroethanol
Descriptor: Brevinin-1BYa
Authors:Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M.
Deposit date:2019-04-02
Release date:2019-09-25
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides.
Eur.Biophys.J., 48, 2019
6R5G
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BU of 6r5g by Molmil
C-SH2 domain of SHP-2 in complex with phospho-ITSM of PD-1
Descriptor: ITSM, Tyrosine-protein phosphatase non-receptor type 11
Authors:Marasco, M.
Deposit date:2019-03-25
Release date:2020-02-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Molecular mechanism of SHP2 activation by PD-1 stimulation.
Sci Adv, 6, 2020
8FG2
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BU of 8fg2 by Molmil
SARS-CoV-2 Nucleocapsid dimer structure determined from COVID-19 patients
Descriptor: Nucleoprotein
Authors:Casasanta, M, Jonaid, G.M, Kaylor, L, Luqiu, W, DiCecco, L, Solares, M, Berry, S, Kelly, D.F.
Deposit date:2022-12-12
Release date:2023-01-11
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structural Insights of the SARS-CoV-2 Nucleocapsid Protein: Implications for the Inner-workings of Rapid Antigen Tests.
Microsc Microanal, 29, 2023
8FD5
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BU of 8fd5 by Molmil
Nucleocapsid monomer structure from SARS-CoV-2
Descriptor: Nucleoprotein
Authors:Casasanta, M, Jonaid, G.M, Kaylor, L, Luqiu, W, DiCecco, L, Solares, M, Berry, S, Kelly, D.F.
Deposit date:2022-12-02
Release date:2023-01-11
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (4.57 Å)
Cite:Structural Insights of the SARS-CoV-2 Nucleocapsid Protein: Implications for the Inner-workings of Rapid Antigen Tests.
Microsc Microanal, 29, 2023
8CPC
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BU of 8cpc by Molmil
3D electron diffraction structure of Hen Egg-White Lysozyme from nano-crystals obtained by high pressure freezing and cryo-sectioning
Descriptor: Lysozyme C
Authors:Moriscot, C, Schoehn, G, Housset, D.
Deposit date:2023-03-02
Release date:2023-09-20
Method:ELECTRON CRYSTALLOGRAPHY (2.91 Å)
Cite:High pressure freezing and cryo-sectioning can be used for protein structure determination by electron diffraction.
Ultramicroscopy, 254, 2023
6Y9B
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BU of 6y9b by Molmil
Cryo-EM structure of trimeric human STEAP1 bound to three Fab120.545 fragments
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, Fab120.545 heavy chain, Fab120.545 light chain, ...
Authors:Oosterheert, W, Gros, P.
Deposit date:2020-03-06
Release date:2020-05-20
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1).
J.Biol.Chem., 295, 2020
8IOG
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BU of 8iog by Molmil
Cryo-EM structure of porcine bc1 complex in isolated state
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, Complex III subunit 9, ...
Authors:Wang, Y.X, Dong, J.Q, Yang, G.F.
Deposit date:2023-03-11
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Cryo-EM structure of porcine bc1 complex in isolated state
To Be Published
6UVR
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BU of 6uvr by Molmil
Human Connexin-26 (Neutral pH open conformation)
Descriptor: Gap junction beta-2 protein
Authors:Khan, A.K, Jagielnicki, M, Purdy, M.D, Yeager, M.
Deposit date:2019-11-04
Release date:2020-04-29
Last modified:2020-05-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:A Steric "Ball-and-Chain" Mechanism for pH-Mediated Regulation of Gap Junction Channels.
Cell Rep, 31, 2020
6V4J
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BU of 6v4j by Molmil
Structure of TrkH-TrkA in complex with ATP
Descriptor: Potassium uptake protein TrkA, Trk system potassium uptake protein TrkH
Authors:Zhou, M, Zhang, H.
Deposit date:2019-11-27
Release date:2020-02-12
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential.
Nat Commun, 11, 2020
6UVT
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BU of 6uvt by Molmil
Human Connexin-26 (Low pH closed conformation)
Descriptor: Gap junction beta-2 protein
Authors:Khan, A.K, Jagielnicki, M, Purdy, M.D, Yeager, M.
Deposit date:2019-11-04
Release date:2020-04-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:A Steric 'Ball-and-Chain' Mechanism for pH-Mediated Regulation of Gap Junction Channels
Cell Rep, 31, 2020
8DK5
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BU of 8dk5 by Molmil
Structure of 187bp LIN28b nucleosome with site 0 mutation
Descriptor: DNA (187-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Lian, T, Guan, R, Bai, Y.
Deposit date:2022-07-02
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
6PQM
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BU of 6pqm by Molmil
Structural Basis for Client Recognition and Activity of Hsp40 Chaperones
Descriptor: Alkaline phosphatase,Chaperone protein DnaJ 2 fusion
Authors:Jiang, Y, Rossi, P, Kalodimos, C.G.
Deposit date:2019-07-09
Release date:2019-09-18
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for client recognition and activity of Hsp40 chaperones.
Science, 365, 2019
8JHF
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BU of 8jhf by Molmil
Native SUV420H1 bound to 167-bp nucleosome
Descriptor: DNA (160-MER), Histone H2A.Z, Histone H2B type 1-K, ...
Authors:Lin, F, Li, W.
Deposit date:2023-05-23
Release date:2023-11-15
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase.
Cell Discov, 9, 2023
8JH2
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BU of 8jh2 by Molmil
RNA polymerase II elongation complex bound with Elf1, Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (218-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JH4
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BU of 8jh4 by Molmil
RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023

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