PDB: 9760 resultsInfo pagesStatus searchChemie searchBIRD

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2ADI	Crystal structure of monoclonal anti-CD4 antibody Q425 in complex with Barium Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BARIUM ION, Q425 Fab Heavy chain, ... Authors: Zhou, T, Hamer, D.H, Hendrickson, W.A, Sattentau, Q.J, Kwong, P.D. Deposit date: 2005-07-20 Release date: 2005-09-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Interfacial metal and antibody recognition. Proc.Natl.Acad.Sci.Usa, 102, 2005
3V7A	Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle Descriptor: 5B18 heavy chain, 5B18 kappa chain, Capsid Authors: Hansman, G.S, Mclellan, J.S, Kwong, P.D. Deposit date: 2011-12-20 Release date: 2012-02-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.297 Å) Cite: Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle. J.Virol., 86, 2012
3TYG	Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with a glycosylated engineered gp120 outer domain with miniV3 (eODmV3) Descriptor: Envelope glycoprotein gp160, PGT128 heavy chain, Ig gamma-1 chain C region, ... Authors: Pejchal, R, Huang, P.S, Schief, W.R, Stanfield, R.L, Wilson, I.A. Deposit date: 2011-09-25 Release date: 2011-10-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.25 Å) Cite: A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science, 334, 2011
4JO2	Crystal structure of rabbit mAb R56 Fab in complex with V3 crown of HIV-1 Consensus A gp120 Descriptor: CALCIUM ION, gp120, monoclonal anti-HIV-1 gp120 V3 antibody R56 heavy chain, ... Authors: Pan, R.M, Kong, X.P. Deposit date: 2013-03-16 Release date: 2013-07-31 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans. J.Virol., 87, 2013
7M1C	Crystal structure of the HCMV pentamer-specific antibody 1-32 Descriptor: 1-32 Fab Heavy Chain, 1-32 Fab Light Chain Authors: Wrapp, D, McLellan, J.S. Deposit date: 2021-03-12 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Sci Adv, 8, 2022
7LYV	Crystal structure of the HCMV pentamer-specific antibody 1-103 Descriptor: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain Authors: Wrapp, D, Jones, H.G, McLellan, J.S. Deposit date: 2021-03-08 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Sci Adv, 8, 2022
7LYW	Crystal structure of the HCMV pentamer-specific antibody 2-25 Descriptor: 2-25 Fab Heavy Chain, 2-25 Fab Light Chain Authors: Wrapp, D, Mishra, A.K, McLellan, J.S. Deposit date: 2021-03-08 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Sci Adv, 8, 2022
8FE4	Structure of dengue virus (DENV2) in complex with prM13, an anti-PrM monoclonal antibody Descriptor: Envelope protein E, prM protein, prM13 Fab Heavy Chain, ... Authors: Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C. Deposit date: 2022-12-05 Release date: 2023-02-01 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (9.8 Å) Cite: prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proc.Natl.Acad.Sci.USA, 120, 2023
8FE3	Structure of dengue virus (DENV2) in complex with prM12, an anti-PrM monoclonal antibody Descriptor: Envelope protein E, prM protein, prM12 Fab Heavy Chain, ... Authors: Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C. Deposit date: 2022-12-05 Release date: 2023-02-01 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (10.2 Å) Cite: prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proc.Natl.Acad.Sci.USA, 120, 2023
3TWC	Crystal structure of broad and potent HIV-1 neutralizing antibody PGT127 in complex with Man9 Descriptor: AMYLAMINE, PGT127 heavy chain, Ig gamma-1 chain C region, ... Authors: Pejchal, R, Wilson, I.A. Deposit date: 2011-09-21 Release date: 2011-10-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.65 Å) Cite: A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science, 334, 2011
1IVL	THE DE NOVO DESIGN OF AN ANTIBODY COMBINING SITE: CRYSTALLOGRAPHIC ANALYSIS OF THE VL DOMAIN CONFIRMS THE STRUCTURAL MODEL Descriptor: IGG-KAPPA M29B FV (LIGHT CHAIN), ISOPROPYL ALCOHOL Authors: Essen, L.-O, Skerra, A. Deposit date: 1994-05-04 Release date: 1994-08-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.17 Å) Cite: The de novo design of an antibody combining site. Crystallographic analysis of the VL domain confirms the structural model. J.Mol.Biol., 238, 1994
2ADJ	Crystal structure of monoclonal anti-CD4 antibody Q425 in complex with Calcium Descriptor: CALCIUM ION, Q425 Fab Heavy chain, Q425 Fab Light chain Authors: Zhou, T, Hamer, D.H, Hendrickson, W.A, Sattentau, Q.J, Kwong, P.D. Deposit date: 2005-07-20 Release date: 2005-09-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Interfacial metal and antibody recognition. Proc.Natl.Acad.Sci.Usa, 102, 2005
5ZUD	Fit R10 Fab coordinates into the cryo-EM of EV71 in complex with D6 Descriptor: Capsid protein VP1, R10 ANTIBODY HEAVY CHAIN, R10 ANTIBODY LIGHT CHAIN, ... Authors: Wang, X, Zhu, L, Wang, N. Deposit date: 2018-05-07 Release date: 2019-12-25 Last modified: 2021-01-06 Method: ELECTRON MICROSCOPY (4.9 Å) Cite: Neutralization Mechanisms of Two Highly Potent Antibodies against Human Enterovirus 71. Mbio, 9, 2018
8K0D	Cryo-EM structure of conformation 2 of complex of Nipah virus attachment G with 1E5 neutralizing antibody Descriptor: Glycoprotein G, The heavy chain of 1E5, The light chain of 1E5 Authors: Sun, M. Deposit date: 2023-07-08 Release date: 2024-05-01 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (2.94 Å) Cite: A potent Henipavirus cross-neutralizing antibody reveals a dynamic fusion-triggering pattern of the G-tetramer. Nat Commun, 15, 2024
8K0C	Cryo-EM structure of conformation 1 of complex of Nipah virus attachment glycoprotein G with 1E5 neutralizing antibody Descriptor: Glycoprotein G, Heavy chain of 1E5 Fab fragments, Light chain of 1E5 Fab fragments Authors: Sun, M.M. Deposit date: 2023-07-08 Release date: 2024-05-01 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: A potent Henipavirus cross-neutralizing antibody reveals a dynamic fusion-triggering pattern of the G-tetramer. Nat Commun, 15, 2024
6RCQ	PfRH5-binding monoclonal antibody R5.011 Descriptor: ACETATE ION, CACODYLATE ION, R5.011 heavy chain, ... Authors: Alanine, D.W.G, Draper, S.J, Higgins, M.K. Deposit date: 2019-04-11 Release date: 2019-06-26 Last modified: 2019-07-10 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019
6RCS	PfRH5-binding monoclonal antibody R5.016 Descriptor: ACETATE ION, R5.016 heavy chain, R5.016 light chain, ... Authors: Alanine, D.W.G, Jamwal, A, Draper, S.J, Higgins, M.K. Deposit date: 2019-04-11 Release date: 2019-06-26 Last modified: 2019-08-21 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019
4GQP	Structure based design of sub-nanomolar affinity anti-methamphetamine single chain antibodies. Descriptor: (2S)-N-methyl-1-phenylpropan-2-amine, Anti-METH scFv Authors: Thakkar, S, Varughese, K.I. Deposit date: 2012-08-23 Release date: 2013-10-02 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Affinity improvement of a therapeutic antibody to methamphetamine and amphetamine through structure-based antibody engineering. Sci Rep, 4, 2014
2AGJ	Crystal Structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Yvo Fab, Heavy Chain, ... Authors: Ramsland, P.A, Terzyan, S.S, Cloud, G, Bourne, C.R, Farrugia, W, Tribbick, G, Geysen, H.M, Moomaw, C.R, Slaughter, C.A, Edmundson, A.B. Deposit date: 2005-07-27 Release date: 2006-05-02 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody Biochem.J., 395, 2006
1NLD	FAB FRAGMENT OF A NEUTRALIZING ANTIBODY DIRECTED AGAINST AN EPITOPE OF GP41 FROM HIV-1 Descriptor: FAB1583 Authors: Davies, C, Beauchamp, J.C, Emery, D, Rawas, A, Muirhead, H. Deposit date: 1996-07-02 Release date: 1996-12-23 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of the Fab fragment from a neutralizing monoclonal antibody directed against an epitope of gp41 from HIV-1. Acta Crystallogr.,Sect.D, 53, 1997
4QWW	Crystal structure of the Fab410-BfAChE complex Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... Authors: Bourne, Y, Renault, L, Marchot, P. Deposit date: 2014-07-17 Release date: 2014-11-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal Structure of Snake Venom Acetylcholinesterase in Complex with Inhibitory Antibody Fragment Fab410 Bound at the Peripheral Site: EVIDENCE FOR OPEN AND CLOSED STATES OF A BACK DOOR CHANNEL. J.Biol.Chem., 290, 2015
3NTC	Crystal structure of KD-247 Fab, an anti-V3 antibody that inhibits HIV-1 Entry Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Fab heavy chain, ... Authors: Sarafianos, S.G, Kirby, K.A. Deposit date: 2010-07-03 Release date: 2010-08-25 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structural basis of clade-specific HIV-1 neutralization by humanized anti-V3 monoclonal antibody KD-247. Faseb J., 29, 2015
6Z3K	Structure of protective antibody 38-1-10A Fab Descriptor: 1,2-ETHANEDIOL, Heavy chain, Light Chain Authors: Zhou, D, Fry, E.E, Ren, J, Stuart, D.I. Deposit date: 2020-05-20 Release date: 2020-09-02 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71. Nat Commun, 11, 2020
3OJD	Anti-Indolicidin monoclonal antibody V2D2 (Fab fragment) Descriptor: Fab V2D2 Authors: Lomash, S, Salunke, D.M. Deposit date: 2010-08-22 Release date: 2010-09-01 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: An antibody as surrogate receptor reveals determinants of activity of an innate immune peptide antibiotic J.Biol.Chem., 285, 2010
7R6X	SARS-CoV-2 spike receptor-binding domain (RBD) in complex with S2E12 Fab, S309 Fab, and S304 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Monoclonal antibody S2E12 Fab heavy chain, ... Authors: Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M. Deposit date: 2021-06-23 Release date: 2021-07-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.95 Å) Cite: SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape. Nature, 597, 2021

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