4QWW

Crystal structure of the Fab410-BfAChE complex

Summary for 4QWW

Entry DOI	10.2210/pdb4qww/pdb
Descriptor	Acetylcholinesterase, Fab410 antibody light chain, Fab410 antibody heavy chain, ... (8 entities in total)
Functional Keywords	a/b hydrolase fold, acetylcholinesterase, monoclonal antibody, hydrolase-immune system complex, hydrolase/immune system
Biological source	Bungarus fasciatus (Banded krait) More
Total number of polymer chains	6
Total formula weight	222193.03
Authors	Bourne, Y.,Renault, L.,Marchot, P. (deposition date: 2014-07-17, release date: 2014-11-26, Last modification date: 2023-09-20)
Primary citation	Bourne, Y.,Renault, L.,Marchot, P. Crystal Structure of Snake Venom Acetylcholinesterase in Complex with Inhibitory Antibody Fragment Fab410 Bound at the Peripheral Site: EVIDENCE FOR OPEN AND CLOSED STATES OF A BACK DOOR CHANNEL. J.Biol.Chem., 290:1522-1535, 2015 Cited by PubMed: 25411244 DOI: 10.1074/jbc.M114.603902 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation