PDB: 1811 resultsInfo pagesStatus searchChemie searchBIRD

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8XU5	The Crystal Structure of RORgT from Biortus. Descriptor: Nuclear receptor ROR-gamma Authors: Wang, F, Cheng, W, Yuan, Z, Qi, J, Wu, B. Deposit date: 2024-01-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (3.5 Å) Cite: The Crystal Structure of RORgT from Biortus. To Be Published
5UAN	Crystal structure of multi-domain RAR-beta-RXR-alpha heterodimer on DNA Descriptor: (9cis)-retinoic acid, DNA (5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*AP*G)-3'), ... Authors: Chandra, V, Wu, D, Kim, Y, Rastinejad, F. Deposit date: 2016-12-19 Release date: 2017-10-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.508 Å) Cite: The quaternary architecture of RAR beta-RXR alpha heterodimer facilitates domain-domain signal transmission. Nat Commun, 8, 2017
4S14	Crystal structure of the orphan nuclear receptor RORgamma ligand-binding domain in complex with 4alpha-caboxyl, 4beta-methyl-zymosterol (4ACD8) Descriptor: (3beta,4alpha,5beta,14beta)-3-hydroxy-4-methylcholesta-8,24-diene-4-carboxylic acid, Nuclear receptor ROR-gamma, Nuclear receptor-interacting protein 1 Authors: Huang, P, Santori, F.R, Littman, D.R, Rastinejad, F. Deposit date: 2015-01-07 Release date: 2015-02-11 Last modified: 2015-02-25 Method: X-RAY DIFFRACTION (3.542 Å) Cite: Identification of Natural ROR gamma Ligands that Regulate the Development of Lymphoid Cells. Cell Metab, 21, 2015
4XAJ	Crystal structure of human NR2E1/TLX Descriptor: Atrophin/grunge, Maltose-binding periplasmic protein,Nuclear receptor subfamily 2 group E member 1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose Authors: Zhi, X, Zhou, E, Xu, E. Deposit date: 2014-12-14 Release date: 2015-03-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.551 Å) Cite: Structural basis for corepressor assembly by the orphan nuclear receptor TLX. Genes Dev., 29, 2015
4OH6	Crystal structure of T877A-AR-LBD bound with co-regulator peptide Descriptor: Androgen receptor, HYDROXYFLUTAMIDE, Protein BUD31 homolog, ... Authors: Liu, J.S, Hsu, C.L, Wu, W.G. Deposit date: 2014-01-17 Release date: 2014-08-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.56 Å) Cite: Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
7KW7	Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ... Authors: Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A. Deposit date: 2020-11-30 Release date: 2021-12-08 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism. Nature, 601, 2022
1BSX	STRUCTURE AND SPECIFICITY OF NUCLEAR RECEPTOR-COACTIVATOR INTERACTIONS Descriptor: 3,5,3'TRIIODOTHYRONINE, PROTEIN (GRIP1), PROTEIN (THYROID HORMONE RECEPTOR BETA) Authors: Wagner, R.L, Darimont, B.D, Apriletti, J.W, Stallcup, M.R, Kushner, P.J, Baxter, J.D, Fletterick, R.J, Yamamoto, K.R. Deposit date: 1998-08-31 Release date: 1999-08-26 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Structure and specificity of nuclear receptor-coactivator interactions. Genes Dev., 12, 1998
4B7W	Ligand binding domain human hepatocyte nuclear factor 4alpha: Apo form Descriptor: HEPATOCYTE NUCLEAR FACTOR 4-ALPHA Authors: Dudasova, Z, Okvist, M, Kretova, M, Ondrovicova, G, Skrabana, R, LeGuevel, R, Salbert, G, Leonard, G, McSweeney, S, Barath, P. Deposit date: 2012-08-24 Release date: 2013-09-11 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (4 Å) Cite: Fatty Acids are not Essential Structural Components of Hepatocyte Nuclear Factor 4Alpha To be Published
6KZ5	Crystal Structure Analysis of the Csn-B-bounded NUR77 Ligand binding Domain Descriptor: Nuclear receptor subfamily 4 group A member 1, ethyl 2-[2-octanoyl-3,5-bis(oxidanyl)phenyl]ethanoate Authors: Hong, W, Chen, H, Wu, Q, Lin, T. Deposit date: 2019-09-23 Release date: 2020-10-14 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (4.45 Å) Cite: Blocking PPAR gamma interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression. Proc.Natl.Acad.Sci.USA, 117, 2020
4UMM	The Cryo-EM structure of the palindromic DNA-bound USP-EcR nuclear receptor reveals an asymmetric organization with allosteric domain positioning Descriptor: 2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE, 5'-D(*CP*AP*AP*GP*GP*GP*TP*TP*CP*AP*AP*TP*GP*CP *AP*CP*TP*TP*GP*TP)-3', 5'-D(*DGP*AP*CP*AP*AP*GP*TP*GP*CP*AP*TP*TP*GP*DAP *AP*CP*CP*CP*TP*T)-3', ... Authors: Maletta, M, Orlov, I, Moras, D, Billas, I.M.L, Klaholz, B.P. Deposit date: 2014-05-19 Release date: 2014-06-25 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (11.6 Å) Cite: The Palindromic DNA-Bound Usp-Ecr Nuclear Receptor Adopts an Asymmetric Organization with Allosteric Domain Positioning. Nat.Commun., 5, 2014
2QMV	High Resolution Structure of Peroxisone Proliferation-Activated Receptor gamma and Characterisation of its Interaction with the Co-activator Transcriptional Intermediary Factor 2 Descriptor: Peroxisome proliferator-activated receptor gamma Authors: Hartl, R, Riepl, H, Kauschke, S, Kalbitzer, H.R, Maurer, T. Deposit date: 2007-07-17 Release date: 2008-09-02 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: High Resolution Structure of Peroxisone Proliferation-Activated Receptor gamma and Characterisation of its Interaction with the Co-activator Transcriptional Intermediary Factor 2 To be Published

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