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8AR3
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BU of 8ar3 by Molmil
Solution structure of TLR9 transmembrane and cytoplasmic juxtamembrane regions
Descriptor: Toll-like receptor 9
Authors:Kornilov, F.D, Shabalkina, A.V, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S.
Deposit date:2022-08-15
Release date:2023-03-22
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors.
Nat Commun, 14, 2023
8AR1
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BU of 8ar1 by Molmil
Solution structure of TLR3 transmembrane and cytoplasmic juxtamembrane regions
Descriptor: Toll-like receptor 3
Authors:Kornilov, F.D, Shabalkina, A.V, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S.
Deposit date:2022-08-15
Release date:2023-03-22
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors.
Nat Commun, 14, 2023
8AR2
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BU of 8ar2 by Molmil
Solution structure of TLR5 transmembrane and cytoplasmic juxtamembrane regions
Descriptor: Toll-like receptor 5
Authors:Shabalkina, A.V, Kornilov, F.D, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S.
Deposit date:2022-08-15
Release date:2023-03-22
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors.
Nat Commun, 14, 2023
7LOH
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BU of 7loh by Molmil
Structure of the HIV-1 gp41 transmembrane domain and cytoplasmic tail
Descriptor: Transmembrane protein gp41
Authors:Piai, A, Fu, Q, Sharp, A.K, Bighi, B, Brown, A.M, Chou, J.J.
Deposit date:2021-02-10
Release date:2021-04-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Model of the Entire Membrane-Interacting Region of the HIV-1 Fusion Protein and Its Perturbation of Membrane Morphology.
J.Am.Chem.Soc., 143, 2021
8EBT
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BU of 8ebt by Molmil
XPA repositioning Core7 of TFIIH relative to XPC-DNA lesion (Cy5)
Descriptor: CALCIUM ION, Centrin-2, DNA, ...
Authors:Kim, J, Yang, W.
Deposit date:2022-08-31
Release date:2023-04-19
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
8J26
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BU of 8j26 by Molmil
CryoEM structure of SARS CoV-2 RBD and Aptamer complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AM032-4, AM047-6, ...
Authors:Rahman, M.S, Jang, S.K, Lee, J.O.
Deposit date:2023-04-14
Release date:2023-06-21
Last modified:2023-07-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure-Guided Development of Bivalent Aptamers Blocking SARS-CoV-2 Infection.
Molecules, 28, 2023
8J1Q
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BU of 8j1q by Molmil
CryoEM structure of SARS CoV-2 RBD and Aptamer complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AM032-0, AM047-0, ...
Authors:Rahman, M.S, Jang, S.K, Lee, J.O.
Deposit date:2023-04-13
Release date:2023-06-21
Last modified:2023-07-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure-Guided Development of Bivalent Aptamers Blocking SARS-CoV-2 Infection.
Molecules, 28, 2023
7LHC
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BU of 7lhc by Molmil
NMR Solution Structure of [T20K]kalata B1
Descriptor: Kalata-B1
Authors:Harvey, P.J, Craik, D.J, Gruber, C.W.
Deposit date:2021-01-22
Release date:2021-10-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Importance of the Cyclic Cystine Knot Structural Motif for Immunosuppressive Effects of Cyclotides.
Acs Chem.Biol., 16, 2021
8AP5
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BU of 8ap5 by Molmil
Cadmium-loaded form of Caenorhabditis elegans MTL-2
Descriptor: CADMIUM ION, Metallothionein-2
Authors:Leszczyszyn, O.I, Sturzenbaum, S.R, Blindauer, C.A.
Deposit date:2022-08-09
Release date:2024-01-17
Method:SOLUTION NMR
Cite:Juggling cadmium detoxification and zinc homeostasis: A division of labour between the two C. elegans metallothioneins.
Chemosphere, 350, 2023
7L8V
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BU of 7l8v by Molmil
NMR Structure of half-calcified calmodulin mutant (CaMEF12) bound to the IQ-motif of CaV1.2
Descriptor: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
Authors:Ames, J.B.
Deposit date:2021-01-01
Release date:2022-07-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Half-calcified calmodulin promotes basal activity and inactivation of the L-type calcium channel Ca V 1.2.
J.Biol.Chem., 298, 2022
7LOI
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BU of 7loi by Molmil
Model of the HIV-1 gp41 membrane-proximal external region, transmembrane domain and cytoplasmic tail
Descriptor: Transmembrane protein gp41
Authors:Piai, A, Fu, Q, Sharp, A.K, Bighi, B, Brown, A.M, Chou, J.J.
Deposit date:2021-02-10
Release date:2021-04-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Model of the Entire Membrane-Interacting Region of the HIV-1 Fusion Protein and Its Perturbation of Membrane Morphology.
J.Am.Chem.Soc., 143, 2021
7LHQ
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BU of 7lhq by Molmil
Solution structure of SARS-CoV-2 nonstructural protein 7 at pH 7.0
Descriptor: Non-structural protein 7
Authors:Lee, Y, Tonelli, M, Anderson, T.K, Kirchdoerfer, R.N, Henzler-Wildman, K, Lee, W.
Deposit date:2021-01-26
Release date:2022-02-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:pH-dependent polymorphism of the structure of SARS-CoV-2 nsp7
Biorxiv, 2021
7LXC
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BU of 7lxc by Molmil
Structure and Interactions of DED1 of human cFLIP
Descriptor: DED1ch
Authors:Panaitiu, A.E, Basiashvili, T, Mierke, D.F, Pellegrini, M.
Deposit date:2021-03-03
Release date:2021-12-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:An engineered construct of cFLIP provides insight into DED1 structure and interactions.
Structure, 30, 2022
7LP4
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BU of 7lp4 by Molmil
Structure of Nedd4L WW3 domain
Descriptor: E3 ubiquitin-protein ligase NEDD4-like
Authors:Alam, S.L, Alian, A, Thompson, T, Rheinemann, L, Volkman, B.F, Peterson, F.C, Sundquist, W.I.
Deposit date:2021-02-11
Release date:2021-07-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Interactions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release.
J.Biol.Chem., 297, 2021
8E6R
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BU of 8e6r by Molmil
Human TRPM2 ion channel in 1 mM dADPR
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Transient receptor potential cation channel subfamily M member 2, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Wang, L, Fu, T.M, Xia, S, Wu, H.
Deposit date:2022-08-23
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:A unified mechanism for human TRPM2 activation, desensitization and inhibition
To Be Published
8B6X
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BU of 8b6x by Molmil
NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in DPC micelles
Descriptor: Envelope glycoprotein gp160
Authors:Jimenez, M.A, Partida-Hanon, A, Nieva, J.L.
Deposit date:2022-09-27
Release date:2022-11-30
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope.
Commun Biol, 5, 2022
8B6Y
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BU of 8b6y by Molmil
NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in the presence of hexafluoroisopropanol
Descriptor: Envelope glycoprotein gp160
Authors:Jimenez, M.A, Partida-Hanon, A, Nieva, J.L.
Deposit date:2022-09-27
Release date:2022-12-07
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope.
Commun Biol, 5, 2022
7M2M
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BU of 7m2m by Molmil
NMR Structure of GCAP5
Descriptor: Guanylate cyclase activator 1A, MAGNESIUM ION
Authors:Ames, J.B, Cudia, D.L.
Deposit date:2021-03-17
Release date:2021-10-20
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:NMR and EPR-DEER Structure of a Dimeric Guanylate Cyclase Activator Protein-5 from Zebrafish Photoreceptors.
Biochemistry, 60, 2021
1HR2
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BU of 1hr2 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF A MUTANT P4-P6 DOMAIN (DELC209) OF TETRAHYMENA THEMOPHILA GROUP I INTRON.
Descriptor: MAGNESIUM ION, P4-P6 DELC209 MUTANT RNA RIBOZYME DOMAIN
Authors:Juneau, K, Podell, E.R, Harrington, D.J, Cech, T.R.
Deposit date:2000-12-20
Release date:2001-04-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions.
Structure, 9, 2001
4NVA
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BU of 4nva by Molmil
Predicting protein conformational response in prospective ligand discovery
Descriptor: Cytochrome c peroxidase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Fischer, M, Fraser, J.S.
Deposit date:2013-12-05
Release date:2013-12-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery.
Nat Chem, 6, 2014
4NVL
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BU of 4nvl by Molmil
Predicting protein conformational response in prospective ligand discovery.
Descriptor: 1-(1H-benzimidazol-1-yl)propan-2-one, Cytochrome c peroxidase, PHOSPHATE ION, ...
Authors:Fischer, M, Fraser, J.S.
Deposit date:2013-12-05
Release date:2013-12-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.432 Å)
Cite:Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery.
Nat Chem, 6, 2014
4NVH
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BU of 4nvh by Molmil
Predicting protein conformational response in prospective ligand discovery
Descriptor: 3-nitroquinolin-4-amine, Cytochrome c peroxidase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Fischer, M, Fraser, J.S.
Deposit date:2013-12-05
Release date:2013-12-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery.
Nat Chem, 6, 2014
7CRH
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BU of 7crh by Molmil
Cryo-EM structure of SKF83959 bound dopamine receptor DRD1-Gs signaling complex
Descriptor: (1S)-6-chloranyl-3-methyl-1-(3-methylphenyl)-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol, D(1A) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Yan, W, Shao, Z.H.
Deposit date:2020-08-13
Release date:2021-03-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.
Cell, 184, 2021
7CKW
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BU of 7ckw by Molmil
Cryo-EM structure of Fenoldopam bound dopamine receptor DRD1-Gs signaling complex
Descriptor: (1R)-6-chloranyl-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ...
Authors:Yan, W, Shao, W.
Deposit date:2020-07-20
Release date:2021-03-03
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.
Cell, 184, 2021
7CKY
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BU of 7cky by Molmil
Cryo-EM structure of PW0464 bound dopamine receptor DRD1-Gs signaling complex
Descriptor: 6-[4-[3-[bis(fluoranyl)methoxy]pyridin-2-yl]oxy-2-methyl-phenyl]-1,5-dimethyl-pyrimidine-2,4-dione, CHOLESTEROL, D(1A) dopamine receptor, ...
Authors:Yan, W, Shao, Z.
Deposit date:2020-07-20
Release date:2021-03-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.
Cell, 184, 2021

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