8E6R
Human TRPM2 ion channel in 1 mM dADPR
Summary for 8E6R
| Entry DOI | 10.2210/pdb8e6r/pdb |
| Related | 6MIZ |
| EMDB information | 27923 |
| Descriptor | Transient receptor potential cation channel subfamily M member 2, ADENOSINE-5-DIPHOSPHORIBOSE, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE (3 entities in total) |
| Functional Keywords | trpm2, trp, adpr, adp-ribose, nudt9h, nudt9, calcium, ion channel, membrane protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 4 |
| Total formula weight | 690139.28 |
| Authors | |
| Primary citation | Wang, L.,Fu, T.-M. A unified mechanism for human TRPM2 activation, desensitization and inhibition To Be Published, |
| Experimental method |
Structure validation
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