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2SKC
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BU of 2skc by Molmil
PYRIDOXAL PHOSPHORYLASE B IN COMPLEX WITH FLUOROPHOSPHATE, GLUCOSE AND INOSINE-5'-MONOPHOSPHATE
Descriptor: FLUORO-PHOSPHITE ION, INOSINIC ACID, PYRIDOXAL PHOSPHORYLASE B, ...
Authors:Oikonomakos, N.G, Zographos, S.E, Tsitsanou, K.E, Johnson, L.N, Acharya, K.R.
Deposit date:1998-12-11
Release date:1998-12-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Activator anion binding site in pyridoxal phosphorylase b: the binding of phosphite, phosphate, and fluorophosphate in the crystal.
Protein Sci., 5, 1996
5OX1
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BU of 5ox1 by Molmil
Glycogen Phosphorylase in complex with JLH270
Descriptor: (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-(4-methoxyphenyl)-1~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ...
Authors:Kyriakis, E, Stravodimos, G.A, Kantsadi, A.L, Chatzileontiadou, D.S.M, Leonidas, D.D.
Deposit date:2017-09-05
Release date:2018-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Bioorg. Chem., 77, 2018
5OWY
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BU of 5owy by Molmil
Glycogen Phosphorylase in complex with KS252
Descriptor: 4-[5-[(2~{S},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-4~{H}-1,2,4-triazol-3-yl]benzoic acid, Glycogen phosphorylase, muscle form, ...
Authors:Kyriakis, E, Stravodimos, G, Kantsadi, A, Chatzileontiadou, D, Leonidas, D.
Deposit date:2017-09-05
Release date:2018-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Bioorg. Chem., 77, 2018
2SKD
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BU of 2skd by Molmil
PYRIDOXAL PHOSPHORYLASE B IN COMPLEX WITH PHOSPHATE, GLUCOSE AND INOSINE-5'-MONOPHOSPHATE
Descriptor: INOSINIC ACID, PHOSPHATE ION, PYRIDOXAL PHOSPHORYLASE B, ...
Authors:Oikonomakos, N.G, Zographos, S.E, Tsitsanou, K.E, Johnson, L.N, Acharya, K.R.
Deposit date:1998-12-11
Release date:1998-12-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Activator anion binding site in pyridoxal phosphorylase b: the binding of phosphite, phosphate, and fluorophosphate in the crystal.
Protein Sci., 5, 1996
5ON2
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BU of 5on2 by Molmil
Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation
Descriptor: 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ...
Authors:Palencia, A, Cusack, S.
Deposit date:2017-08-02
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase.
J. Mol. Biol., 430, 2018
6SHK
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BU of 6shk by Molmil
High resolution structure of the antimicrobial peptide Dermcidin from human
Descriptor: Dermcidin, ZINC ION
Authors:Zeth, K.
Deposit date:2019-08-07
Release date:2019-09-25
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.992 Å)
Cite:Crystal Structure and Functional Mechanism of a Human Antimicrobial Membrane Channel
To be published
3OEH
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BU of 3oeh by Molmil
Structure of four mutant forms of yeast F1 ATPase: beta-V279F
Descriptor: ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase subunit delta, ...
Authors:Arsenieva, D, Symersky, J, Wang, Y, Pagadala, V, Mueller, D.M.
Deposit date:2010-08-12
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of mutant forms of the yeast f1 ATPase reveal two modes of uncoupling.
J.Biol.Chem., 285, 2010
3NP9
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BU of 3np9 by Molmil
Glycogen phosphorylase complexed with 3-(beta-D-glucopyranosyl)-2-hydroxy-5-methoxy-chlorobenzene
Descriptor: (1S)-1,5-anhydro-1-(3-chloro-2-hydroxy-5-methoxyphenyl)-D-glucitol, Glycogen phosphorylase, muscle form
Authors:Alexacou, K.-M.
Deposit date:2010-06-28
Release date:2011-06-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Halogen-substituted (C-beta-D-glucopyranosyl)-hydroquinone regioisomers: synthesis, enzymatic evaluation and their binding to glycogen phosphorylase.
Bioorg.Med.Chem., 19, 2011
4HX6
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BU of 4hx6 by Molmil
Streptomyces globisporus C-1027 NADH:FAD oxidoreductase SgcE6
Descriptor: ACETATE ION, Oxidoreductase, SULFATE ION
Authors:Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2012-11-09
Release date:2012-11-28
Last modified:2016-12-07
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.
Biochemistry, 55, 2016
4I7E
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BU of 4i7e by Molmil
Crystal Structure of the Bacillus stearothermophilus Phosphofructokinase Mutant D12A in Complex with PEP
Descriptor: 6-phosphofructokinase, PHOSPHOENOLPYRUVATE
Authors:Mosser, R, Reddy, M, Bruning, J.B, Sacchettini, J.C, Reinhart, G.D.
Deposit date:2012-11-30
Release date:2013-07-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Redefining the Role of the Quaternary Shift in Bacillus stearothermophilus Phosphofructokinase.
Biochemistry, 52, 2013
4I36
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BU of 4i36 by Molmil
Crystal Structure of the Bacillus stearothermophilus Phosphofructokinase Mutant D12A
Descriptor: 6-phosphofructokinase
Authors:Mosser, R, Reddy, M, Bruning, J.B, Sacchettini, J.C, Reinhart, G.D.
Deposit date:2012-11-25
Release date:2013-07-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Redefining the Role of the Quaternary Shift in Bacillus stearothermophilus Phosphofructokinase.
Biochemistry, 52, 2013
3MS2
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BU of 3ms2 by Molmil
Glycogen phosphorylase complexed with 4-methylbenzaldehyde-4-(beta-D-glucopyranosyl) thiosemicarbazone
Descriptor: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-methylphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine
Authors:Alexacou, K.-M.
Deposit date:2010-04-29
Release date:2011-01-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors
Bioorg.Med.Chem., 18, 2010
3MT9
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BU of 3mt9 by Molmil
Glycogen phosphorylase complexed with 4-nitrobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone
Descriptor: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-nitrophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine
Authors:Alexacou, K.-M.
Deposit date:2010-04-30
Release date:2011-01-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors
Bioorg.Med.Chem., 18, 2010
3MRX
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BU of 3mrx by Molmil
Glycogen phosphorylase complexed with 4-methoxybenzaldehyde-4-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-thiosemicarbazone
Descriptor: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-methoxyphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine
Authors:Alexacou, K.-M.
Deposit date:2010-04-29
Release date:2011-01-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors
Bioorg.Med.Chem., 18, 2010
3MF1
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BU of 3mf1 by Molmil
Crystal structure of class II aaRS homologue (Bll0957) complexed with an analogue of glycyl adenylate
Descriptor: 5'-O-(glycylsulfamoyl)adenosine, Bll0957 protein, ZINC ION
Authors:Weygand-Durasevic, I, Mocibob, M, Ivic, N, Bilokapic, S, Maier, T, Luic, M, Ban, N.
Deposit date:2010-04-01
Release date:2010-07-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
2VC4
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BU of 2vc4 by Molmil
Ricin A-Chain (Recombinant) E177D Mutant
Descriptor: GLYCEROL, RICIN A CHAIN, SULFATE ION
Authors:Marsden, C.J, Fulop, V.
Deposit date:2007-09-18
Release date:2007-10-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:The Isolation and Characterisation of Temperature-Dependent Ricin a Chain Molecules in Saccharomyces Cerevisiae
FEBS J., 274, 2007
3MQF
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BU of 3mqf by Molmil
Glycogen phosphorylase complexed with 4-fluorobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone
Descriptor: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-fluorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine
Authors:Alexacou, K.-M.
Deposit date:2010-04-28
Release date:2011-01-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors
Bioorg.Med.Chem., 18, 2010
3MRT
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BU of 3mrt by Molmil
Glycogen phosphorylase complexed with 4-pyridinecarboxaldehyde-4-(beta-D-glucopyranosyl) thiosemicarbazone
Descriptor: Glycogen phosphorylase, muscle form, N-{[(2E)-2-(pyridin-4-ylmethylidene)hydrazino]carbonothioyl}-beta-D-glucopyranosylamine
Authors:Alexacou, K.-M.
Deposit date:2010-04-29
Release date:2011-01-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors
Bioorg.Med.Chem., 18, 2010
3MSC
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BU of 3msc by Molmil
Glycogen phosphorylase complexed with 2-nitrobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone
Descriptor: Glycogen phosphorylase, muscle form, N-({(2Z)-2-[(2-nitrophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine
Authors:Alexacou, K.-M.
Deposit date:2010-04-29
Release date:2011-03-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:The binding of beta-d-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors.
Bioorg.Med.Chem., 18, 2010
2VC3
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BU of 2vc3 by Molmil
Ricin A-Chain (Recombinant) E177D Mutant with a bound acetate
Descriptor: ACETATE ION, RICIN A CHAIN, SULFATE ION
Authors:Marsden, C.J, Fulop, V.
Deposit date:2007-09-18
Release date:2007-10-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Isolation and Characterisation of Temperature-Dependent Ricin a Chain Molecules in Saccharomyces Cerevisiae
FEBS J., 274, 2007
2W5G
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BU of 2w5g by Molmil
RNASE A-5'-ATP COMPLEX
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RIBONUCLEASE PANCREATIC
Authors:Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R.
Deposit date:2008-12-10
Release date:2009-02-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Influence of Naturally-Occurring 5'-Pyrophosphate- Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study.
Biopolymers, 91, 2009
3MRV
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BU of 3mrv by Molmil
Glycogen phosphorylase complexed with 3-hydroxybenzaldehyde-4-(beta-D-glucopyranosyl) thiosemicarbazone
Descriptor: DIMETHYL SULFOXIDE, Glycogen phosphorylase, muscle form, ...
Authors:Alexacou, K.-M.
Deposit date:2010-04-29
Release date:2011-01-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors
Bioorg.Med.Chem., 18, 2010
3MT8
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BU of 3mt8 by Molmil
Glycogen phosphorylase complexed with 4-chlorobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone
Descriptor: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-chlorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine
Authors:Alexacou, K.-M.
Deposit date:2010-04-30
Release date:2011-01-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors
Bioorg.Med.Chem., 18, 2010
8J4I
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BU of 8j4i by Molmil
Unveiling the Role of Human Prohibitin 2 as a Mitochondrial Calcium Channel in Parkinson's Disease
Descriptor: Prohibitin-2
Authors:Li, Y.Y, Fang, Y, Gao, Y.X, Ding, W, Yang, J, Liu, Y, Shen, B, Wang, J.F, Zhou, S.
Deposit date:2023-04-20
Release date:2024-06-05
Method:SOLUTION NMR
Cite:Human Prohibitin 2 is a Mitochondrial Ca2+-Selective Channel
To Be Published
4H1S
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BU of 4h1s by Molmil
Crystal Structure of a Truncated Soluble form of Human CD73 with Ecto-5'-Nucleotidase activity
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-nucleotidase, PHOSPHATE ION, ...
Authors:Heuts, D.P, Weissenborn, M.J, Olkhov, R.V, Shaw, A.M, Levy, C.W, Scrutton, N.S.
Deposit date:2012-09-11
Release date:2012-10-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a soluble form of human CD73 with ecto-5'-nucleotidase activity.
Chembiochem, 13, 2012

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