6NON
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![BU of 6non by Molmil](/molmil-images/mine/6non) | Structure of Cyanthece apo McdA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cobyrinic acid ac-diamide synthase, MAGNESIUM ION | Authors: | Schumacher, M.A. | Deposit date: | 2019-01-16 | Release date: | 2019-04-24 | Last modified: | 2019-06-26 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs. Nucleic Acids Res., 47, 2019
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6NOP
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![BU of 6nop by Molmil](/molmil-images/mine/6nop) | Structure of Cyanothece McdA(D38A)-ATP complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cobyrinic acid ac-diamide synthase, MAGNESIUM ION | Authors: | Schumacher, M.A. | Deposit date: | 2019-01-16 | Release date: | 2019-04-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs. Nucleic Acids Res., 47, 2019
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7U8F
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![BU of 7u8f by Molmil](/molmil-images/mine/7u8f) | Ternary complex structure of Cereblon-DDB1 bound to IKZF2(ZF2) and the molecular glue DKY709 | Descriptor: | (3S)-3-[5-(1-benzylpiperidin-4-yl)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA damage-binding protein 1, ... | Authors: | Ma, X, Ornelas, E, Clifton, M.C. | Deposit date: | 2022-03-08 | Release date: | 2023-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy. Cell Chem Biol, 30, 2023
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8GA8
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![BU of 8ga8 by Molmil](/molmil-images/mine/8ga8) | Structure of the yeast (HDAC) Rpd3L complex | Descriptor: | Histone deacetylase RPD3, Transcriptional regulatory protein DEP1, Transcriptional regulatory protein PHO23, ... | Authors: | Patel, A.B, Radhakrishnan, I, He, Y. | Deposit date: | 2023-02-22 | Release date: | 2023-07-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex. Nat Commun, 14, 2023
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6FTS
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![BU of 6fts by Molmil](/molmil-images/mine/6fts) | TETR(D) N82A MUTANT IN COMPLEX WITH PEG4 | Descriptor: | CHLORIDE ION, TETRAETHYLENE GLYCOL, Tetracycline repressor protein class D | Authors: | Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B. | Deposit date: | 2018-02-23 | Release date: | 2019-02-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding. Biochim Biophys Acta Proteins Proteom, 1868, 2020
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6FPL
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![BU of 6fpl by Molmil](/molmil-images/mine/6fpl) | TETR(D) E147A MUTANT IN COMPLEX WITH TETRACYCLINE AND MAGNESIUM | Descriptor: | CHLORIDE ION, MAGNESIUM ION, TETRACYCLINE, ... | Authors: | Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B. | Deposit date: | 2018-02-11 | Release date: | 2019-03-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.602 Å) | Cite: | Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding. Biochim Biophys Acta Proteins Proteom, 1868, 2020
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5CYV
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![BU of 5cyv by Molmil](/molmil-images/mine/5cyv) | Crystal structure of CouR from Rhodococcus jostii RHA1 bound to p-coumaroyl-CoA | Descriptor: | ACETATE ION, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Stogios, P.J, Xu, X, Dong, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-07-30 | Release date: | 2015-08-12 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | The activity of CouR, a MarR family transcriptional regulator, is modulated through a novel molecular mechanism. Nucleic Acids Res., 44, 2016
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2OEN
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![BU of 2oen by Molmil](/molmil-images/mine/2oen) | Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors glucose-6-phosphate and fructose-1,6-bisphosphate | Descriptor: | Catabolite control protein, Phosphocarrier protein HPr | Authors: | Schumacher, M.A, Seidel, G, Hillen, W, Brennan, R.G. | Deposit date: | 2006-12-30 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Structural Mechanism for the Fine-tuning of CcpA Function by The Small Molecule Effectors Glucose 6-Phosphate and Fructose 1,6-Bisphosphate. J.Mol.Biol., 368, 2007
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6WPA
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![BU of 6wpa by Molmil](/molmil-images/mine/6wpa) | |
4A0X
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![BU of 4a0x by Molmil](/molmil-images/mine/4a0x) | Structure of the global transcription regulator FapR from Staphylococcus aureus | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, TRANSCRIPTION FACTOR FAPR, ... | Authors: | Albanesi, D, Guerin, M.E, Buschiazzo, A, de Mendoza, D, Alzari, P.M. | Deposit date: | 2011-09-13 | Release date: | 2012-09-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus Aureus. Plos Pathog., 9, 2013
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7EGP
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![BU of 7egp by Molmil](/molmil-images/mine/7egp) | The structure of SWI/SNF-nucleosome complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP9, Actin-related protein 7, ... | Authors: | Chen, Z.C, Chen, K.J, He, Z.Y, Ye, Y.P. | Deposit date: | 2021-03-24 | Release date: | 2022-01-12 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularity. Cell Discov, 7, 2021
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4ZIA
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![BU of 4zia by Molmil](/molmil-images/mine/4zia) | Crystal Structure of STAT3 N-terminal domain | Descriptor: | FORMIC ACID, MAGNESIUM ION, NICKEL (II) ION, ... | Authors: | Hu, T, Chopra, R. | Deposit date: | 2015-04-28 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Impact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional Activity. Mol.Cell.Biol., 35, 2015
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4A0Z
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![BU of 4a0z by Molmil](/molmil-images/mine/4a0z) | Structure of the global transcription regulator FapR from Staphylococcus aureus in complex with malonyl-CoA | Descriptor: | MALONYL-COENZYME A, TRANSCRIPTION FACTOR FAPR | Authors: | Albanesi, D, Guerin, M.E, Buschiazzo, A, de Mendoza, D, Alzari, P.M. | Deposit date: | 2011-09-13 | Release date: | 2012-09-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus Aureus. Plos Pathog., 9, 2013
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4A0Y
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![BU of 4a0y by Molmil](/molmil-images/mine/4a0y) | Structure of the global transcription regulator FapR from Staphylococcus aureus | Descriptor: | CHLORIDE ION, TRANSCRIPTION FACTOR FAPR | Authors: | Albanesi, D, Guerin, M.E, Buschiazzo, A, de Mendoza, D, Alzari, P.M. | Deposit date: | 2011-09-13 | Release date: | 2012-09-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus Aureus. Plos Pathog., 9, 2013
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3KEO
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![BU of 3keo by Molmil](/molmil-images/mine/3keo) | Crystal Structure of a Rex-family transcriptional regulatory protein from Streptococcus agalactiae complexed with NAD+ | Descriptor: | CHLORIDE ION, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Thiyagarajan, S, Logan, D, von Wachenfeldt, C. | Deposit date: | 2009-10-26 | Release date: | 2010-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | NAD+ pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence. Plos Pathog., 17, 2021
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5HYZ
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![BU of 5hyz by Molmil](/molmil-images/mine/5hyz) | Crystal Structure of SCL7 in Oryza sativa | Descriptor: | GRAS family transcription factor containing protein, expressed | Authors: | Wu, Y, Li, S, Zhao, Y, Sun, L. | Deposit date: | 2016-02-02 | Release date: | 2016-04-27 | Last modified: | 2016-06-29 | Method: | X-RAY DIFFRACTION (1.822 Å) | Cite: | Crystal Structure of the GRAS Domain of SCARECROW-LIKE7 in Oryza sativa. Plant Cell, 28, 2016
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3HHG
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![BU of 3hhg by Molmil](/molmil-images/mine/3hhg) | Structure of CrgA, a LysR-type transcriptional regulator from Neisseria meningitidis. | Descriptor: | Transcriptional regulator, LysR family | Authors: | Sainsbury, S, Ren, J, Owens, R.J, Stuart, D.I, Oxford Protein Production Facility (OPPF) | Deposit date: | 2009-05-15 | Release date: | 2009-07-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators Nucleic Acids Res., 37, 2009
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3KEQ
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4RNP
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![BU of 4rnp by Molmil](/molmil-images/mine/4rnp) | BACTERIOPHAGE T7 RNA POLYMERASE, HIGH SALT CRYSTAL FORM, LOW TEMPERATURE DATA, ALPHA-CARBONS ONLY | Descriptor: | RNA POLYMERASE | Authors: | Liu, Z.J, Sousa, R, Rose, J.P, Wang, B.C. | Deposit date: | 1997-09-11 | Release date: | 1997-12-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of bacteriophage T7 RNA polymerase at 3.3 A resolution. Nature, 364, 1993
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6A2T
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![BU of 6a2t by Molmil](/molmil-images/mine/6a2t) | Mycobacterium tuberculosis LexA C-domain K197A | Descriptor: | ACRYLIC ACID, LexA repressor | Authors: | Chandran, A.V, Srikalaivani, R, Paul, A, Vijayan, M. | Deposit date: | 2018-06-12 | Release date: | 2019-01-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Biochemical characterization of Mycobacterium tuberculosis LexA and structural studies of its C-terminal segment. Acta Crystallogr D Struct Biol, 75, 2019
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6SDG
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![BU of 6sdg by Molmil](/molmil-images/mine/6sdg) | |
2ZOZ
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![BU of 2zoz by Molmil](/molmil-images/mine/2zoz) | Crystal structure of the ethidium-bound form of the multi-drug binding transcriptional repressor CgmR | Descriptor: | ETHIDIUM, GLYCEROL, SULFATE ION, ... | Authors: | Itou, H, Shirakihara, Y, Tanaka, I. | Deposit date: | 2008-06-20 | Release date: | 2008-07-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structures of the Multidrug Binding Repressor Corynebacteriumglutamicum CgmR in Complex with Inducers and with an Operator J.Mol.Biol., 403, 2010
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7KTR
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![BU of 7ktr by Molmil](/molmil-images/mine/7ktr) | Cryo-EM structure of the human SAGA coactivator complex (TRRAP, core) | Descriptor: | Ataxin-7, INOSITOL HEXAKISPHOSPHATE, Isoform 3 of Transcription factor SPT20 homolog, ... | Authors: | Herbst, D.A, Esbin, M.N, Nogales, E. | Deposit date: | 2020-11-24 | Release date: | 2021-11-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structure of the human SAGA coactivator complex. Nat.Struct.Mol.Biol., 28, 2021
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7KTS
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![BU of 7kts by Molmil](/molmil-images/mine/7kts) | Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module) | Descriptor: | Ataxin-7, Isoform 3 of Transcription factor SPT20 homolog, STAGA complex 65 subunit gamma, ... | Authors: | Herbst, D.A, Esbin, M.N, Nogales, E. | Deposit date: | 2020-11-24 | Release date: | 2021-11-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (19.09 Å) | Cite: | Structure of the human SAGA coactivator complex. Nat.Struct.Mol.Biol., 28, 2021
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7SVW
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![BU of 7svw by Molmil](/molmil-images/mine/7svw) | Strand-transfer complex of TnsB from ShCAST | Descriptor: | MAGNESIUM ION, STC_LE_For, STC_LE_Rev1, ... | Authors: | Park, J, Tsai, A.W.T, Kellogg, E.H. | Deposit date: | 2021-11-19 | Release date: | 2022-08-10 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM. Proc.Natl.Acad.Sci.USA, 119, 2022
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