3KEO

Crystal Structure of a Rex-family transcriptional regulatory protein from Streptococcus agalactiae complexed with NAD+

Summary for 3KEO

• Entry DOI: 10.2210/pdb3keo/pdb
• Related: 2dt5 2vt3 3KEQ 3KET
• Descriptor: Redox-sensing transcriptional repressor rex, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: dna binding protein, winged helix, rossmann fold, nad+, repressor, transcription, transcription regulation, redox sensing
• Biological source: Streptococcus agalactiae serogroup III
• Cellular location: Cytoplasm : Q8E565
• Total number of polymer chains: 2
• Total formula weight: 49233.16

Authors

Thiyagarajan, S.,Logan, D.,von Wachenfeldt, C. (deposition date: 2009-10-26, release date: 2010-11-10, Last modification date: 2023-11-01)

• Primary citation: Franza, T.,Rogstam, A.,Thiyagarajan, S.,Sullivan, M.J.,Derre-Bobillot, A.,Bauer, M.C.,Goh, K.G.K.,Da Cunha, V.,Glaser, P.,Logan, D.T.,Ulett, G.C.,von Wachenfeldt, C.,Gaudu, P.; NAD+ pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence.; Plos Pathog., 17:e1009791-e1009791, 2021; PubMed: 34370789; DOI: 10.1371/journal.ppat.1009791

Experimental method

X-RAY DIFFRACTION (1.5 Å)