3KEQ
Crystal structure of a Rex-family transcriptional regulatory protein from Streptococcus agalactiae complexed with NAD+
Summary for 3KEQ
Entry DOI | 10.2210/pdb3keq/pdb |
Related | 2dt5 2vt3 3KEO |
Descriptor | Redox-sensing transcriptional repressor rex, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total) |
Functional Keywords | dna binding protein, winged helix, rossmann fold, nad+, repressor, transcription, transcription regulation, redox sensing |
Biological source | Streptococcus agalactiae serogroup III |
Cellular location | Cytoplasm : Q8E565 |
Total number of polymer chains | 2 |
Total formula weight | 48364.14 |
Authors | Thiyagarajan, S.,Logan, D.,von Wachenfeldt, C. (deposition date: 2009-10-26, release date: 2010-11-10, Last modification date: 2023-11-01) |
Primary citation | Franza, T.,Rogstam, A.,Thiyagarajan, S.,Sullivan, M.J.,Derre-Bobillot, A.,Bauer, M.C.,Goh, K.G.K.,Da Cunha, V.,Glaser, P.,Logan, D.T.,Ulett, G.C.,von Wachenfeldt, C.,Gaudu, P. NAD+ pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence. Plos Pathog., 17:e1009791-e1009791, 2021 Cited by PubMed: 34370789DOI: 10.1371/journal.ppat.1009791 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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