5LSQ
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![BU of 5lsq by Molmil](/molmil-images/mine/5lsq) | Ethylene Forming Enzyme from Pseudomonas syringae pv. phaseolicola - I222 crystal form | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Ethylene Forming Enzyme, ... | Authors: | Zhang, Z, McDonough, M.A, Schofield, C.J. | Deposit date: | 2016-09-05 | Release date: | 2017-04-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5LGT
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![BU of 5lgt by Molmil](/molmil-images/mine/5lgt) | Thieno[3,2-b]pyrrole-5-carboxamides as Novel Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1: Compound 15 | Descriptor: | 4-methyl-~{N}-[2-[[4-(1-methylpiperidin-4-yl)oxyphenoxy]methyl]phenyl]thieno[3,2-b]pyrrole-5-carboxamide, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, ... | Authors: | Mattevi, A, Ciossani, G. | Deposit date: | 2016-07-08 | Release date: | 2017-02-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship. J. Med. Chem., 60, 2017
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8ERF
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5LT0
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8EOY
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8ERH
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8P6I
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![BU of 8p6i by Molmil](/molmil-images/mine/8p6i) | Crystal structure of the 139H2 Fab fragment bound to Muc1 peptide epitope | Descriptor: | 139H2 HC, 139H2 LC, Mucin-1 | Authors: | Beugelink, J.W, Peng, W, Siborova, M, Pronker, M.F, Snijder, J, Janssen, B.J.C. | Deposit date: | 2023-05-26 | Release date: | 2024-04-03 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Reverse-engineering the anti-MUC1 antibody 139H2 by mass spectrometry-based de novo sequencing. Life Sci Alliance, 7, 2024
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6XI1
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![BU of 6xi1 by Molmil](/molmil-images/mine/6xi1) | Crystal structure of tetra-tandem repeat in extending RTX adhesin from Aeromonas hydrophila | Descriptor: | CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Ye, Q, Vance, T.D.R, Conroy, B, Davies, P.L. | Deposit date: | 2020-06-19 | Release date: | 2020-10-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Essential role of calcium in extending RTX adhesins to their target. J Struct Biol X, 4, 2020
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7UAJ
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![BU of 7uaj by Molmil](/molmil-images/mine/7uaj) | Crystal structure of apo HPV16 E6 | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Protein E6, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Shen, Q, Leonard, P.G, Cross, J.B. | Deposit date: | 2022-03-13 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Disorder-to-order transition of the interdomain linker of HPV E6 upon E6AP binding reshapes p53 binding pocket To Be Published
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5LUH
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![BU of 5luh by Molmil](/molmil-images/mine/5luh) | AadA E87Q in complex with ATP, calcium and streptomycin | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | Authors: | Stern, A.L, Van der Verren, S.E, Selmer, M. | Deposit date: | 2016-09-08 | Release date: | 2018-01-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase fromSalmonella enterica. J.Biol.Chem., 293, 2018
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8OLH
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7UW2
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![BU of 7uw2 by Molmil](/molmil-images/mine/7uw2) | Crystal structure of human Retinoid X receptor alpha ligand binding domain complex with UAB116 and coactivator peptide GRIP-1 | Descriptor: | (2E,4E,6Z,8E)-8-{3-[(2S)-butan-2-yl]-2-(3-methylbutyl)cyclohex-2-en-1-ylidene}-3,7-dimethylocta-2,4,6-trienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | Authors: | Chattopadhyay, D, Yang, Z, Atigadda, V. | Deposit date: | 2022-05-02 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Conformationally Defined Rexinoids for the Prevention of Inflammation and Nonmelanoma Skin Cancers. J.Med.Chem., 65, 2022
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5LUV
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8OMC
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7UW4
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![BU of 7uw4 by Molmil](/molmil-images/mine/7uw4) | Crystal structure of human Retinoid X receptor alpha ligand binding domain complex with UAB113 and coactivator peptide GRIP-1 | Descriptor: | (2E,4E,6Z,8E)-3,7-dimethyl-8-[2-(3-methylbutyl)-3-propylcyclohex-2-en-1-ylidene]octa-2,4,6-trienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | Authors: | Chattopadhyay, D, Yang, Z, Atigadda, V. | Deposit date: | 2022-05-02 | Release date: | 2023-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Conformationally Defined Rexinoids for the Prevention of Inflammation and Nonmelanoma Skin Cancers. J.Med.Chem., 65, 2022
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8EI9
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![BU of 8ei9 by Molmil](/molmil-images/mine/8ei9) | Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H332, a Helicon Polypeptide | Descriptor: | Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H332, ... | Authors: | Li, K, Travaline, T.L, Swiecicki, J.-M, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H. | Deposit date: | 2022-09-14 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun, 14, 2023
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8ONR
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8EI8
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![BU of 8ei8 by Molmil](/molmil-images/mine/8ei8) | Crystal structure of the WWP2 HECT domain in complex with H308, a Helicon Polypeptide | Descriptor: | 1,2-ETHANEDIOL, H308, N,N'-(1,4-phenylene)diacetamide, ... | Authors: | Li, K, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H. | Deposit date: | 2022-09-14 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun, 14, 2023
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8ONM
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![BU of 8onm by Molmil](/molmil-images/mine/8onm) | Crystal structure of D-amino acid aminotransferase from Aminobacterium colombiense point mutant E113A complexed with D-glutamate | Descriptor: | (~{Z})-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]pent-2-enedioic acid, 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Matyuta, I.O, Boyko, K.M, Minyaev, M.E, Shilova, S.A, Bezsudnova, E.Y, Popov, V.O. | Deposit date: | 2023-04-03 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Probing of the structural and catalytic roles of the residues in the active site of transaminase from Aminobacterium colombiense To Be Published
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7ULY
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![BU of 7uly by Molmil](/molmil-images/mine/7uly) | MicroED structure of triclinic lysozyme | Descriptor: | Lysozyme C, NITRATE ION | Authors: | Clabbers, M.T.B, Martynowycz, M.W, Hattne, J, Gonen, T. | Deposit date: | 2022-04-05 | Release date: | 2023-03-15 | Method: | ELECTRON CRYSTALLOGRAPHY (0.87 Å) | Cite: | Hydrogens and hydrogen-bond networks in macromolecular MicroED data. J Struct Biol X, 6, 2022
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8ERE
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5LC9
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8EI1
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![BU of 8ei1 by Molmil](/molmil-images/mine/8ei1) | Crystal structure of the N-terminal domain of CUL4B in complex with H316, a Helicon Polypeptide | Descriptor: | Cullin-4B, H316, N,N'-(1,4-phenylene)diacetamide | Authors: | Li, K, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H. | Deposit date: | 2022-09-14 | Release date: | 2023-10-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun, 14, 2023
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8OKF
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![BU of 8okf by Molmil](/molmil-images/mine/8okf) | WD repeat containing protein 5 (WDR5)- PER2 peptide | Descriptor: | CHLORIDE ION, Glutathione S-transferase class-mu 26 kDa isozyme,WD repeat domain 5, PENTAETHYLENE GLYCOL, ... | Authors: | Wolf, E, Boergel, A. | Deposit date: | 2023-03-28 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A structural competition involving WDR5 times circadian oscillations To Be Published
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8ERG
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![BU of 8erg by Molmil](/molmil-images/mine/8erg) | |