8XMZ
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7O4D
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![BU of 7o4d by Molmil](/molmil-images/mine/7o4d) | QR2 inhibitor from a novel sulfanamide series to tackle age related oxidative stress and cognitive decline | Descriptor: | 8-methyl-2-(4-methyl-3-piperazin-1-ylsulfonyl-phenyl)imidazo[1,2-a]pyridine, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | Authors: | Gould, N.L, Scherer, G.R, Carvalh, S, Shurrush, K, Edry, E, Elkobi, A, David, O, Dym, O, Albeck, S, Peleg, Y, Germain, N, Babaev, I, Sharir, H, Lefker, B, Subramanyam, C, Barr, H, Rosenblum, K. | Deposit date: | 2021-04-06 | Release date: | 2022-08-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.249 Å) | Cite: | Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice. J.Clin.Invest., 133, 2023
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6THD
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![BU of 6thd by Molmil](/molmil-images/mine/6thd) | Multiple Genomic RNA-Coat Protein Contacts Play Vital Roles in the Assembly of Infectious Enterovirus-E | Descriptor: | Genome polyprotein, MYRISTIC ACID, SULFATE ION | Authors: | Chandler-Bostock, R, Mata, C.P, Bingham, R, Dykeman, E.J, Meng, B, Tuthill, T.J, Rowlands, D.J, Ranson, N.A, Twarock, R, Stockley, P.G. | Deposit date: | 2019-11-19 | Release date: | 2020-12-09 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.23 Å) | Cite: | Assembly of infectious enteroviruses depends on multiple, conserved genomic RNA-coat protein contacts. Plos Pathog., 16, 2020
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4YM8
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8Y0W
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8XXA
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8Y1R
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![BU of 8y1r by Molmil](/molmil-images/mine/8y1r) | in situ room temperature Laue crystallography | Descriptor: | Lysozyme C | Authors: | Wang, Z.J, Wang, S.S, Pan, Q.Y, Yu, L, Su, Z.H, Yang, T.Y, Wang, Y.Z, Zhang, W.Z, Hao, Q, Gao, X.Y. | Deposit date: | 2024-01-25 | Release date: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | BL03HB: Laue crystallography beamline at SSRF To Be Published
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8Y0X
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![BU of 8y0x by Molmil](/molmil-images/mine/8y0x) | Dormant ribosome with SERBP1 | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Du, M, Zeng, F. | Deposit date: | 2024-01-23 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The global structure of dormant ribosome To Be Published
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4YOQ
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![BU of 4yoq by Molmil](/molmil-images/mine/4yoq) | Crystal Structure of MutY bound to its anti-substrate | Descriptor: | A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(*T*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ... | Authors: | Wang, L, Lee, S, Verdine, G.L. | Deposit date: | 2015-03-11 | Release date: | 2015-05-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase. J.Biol.Chem., 290, 2015
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8XX9
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![BU of 8xx9 by Molmil](/molmil-images/mine/8xx9) | Rhodothermus marinus alpha-amylase RmGH13_47A CBM48-A-B-C domains | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Tonozuka, T. | Deposit date: | 2024-01-18 | Release date: | 2024-02-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural basis for the recognition of alpha-1,6-branched alpha-glucan by GH13_47 alpha-amylase from Rhodothermus marinus. Proteins, 2024
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4YNU
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![BU of 4ynu by Molmil](/molmil-images/mine/4ynu) | Crystal structure of Aspergillus flavus FADGDH in complex with D-glucono-1,5-lactone | Descriptor: | D-glucono-1,5-lactone, FLAVIN-ADENINE DINUCLEOTIDE, Glucose oxidase, ... | Authors: | Yoshida, H, Sakai, G, Kojima, K, Kamitori, S, Sode, K. | Deposit date: | 2015-03-11 | Release date: | 2015-09-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structural analysis of fungus-derived FAD glucose dehydrogenase Sci Rep, 5, 2015
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8YA1
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![BU of 8ya1 by Molmil](/molmil-images/mine/8ya1) | HEN EGG WHITE LYSOZYME | Descriptor: | Lysozyme C | Authors: | Zhang, C.Y, Xu, Q, Wang, W.W, Zhou, H. | Deposit date: | 2024-02-07 | Release date: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Crystallographic data collection using a multilayer monochromator on an undulator beamline at SSRF To Be Published
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8YBG
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3JC9
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![BU of 3jc9 by Molmil](/molmil-images/mine/3jc9) | Architectural model of the type IVa pilus machine in a non-piliated state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PilA, ... | Authors: | Chang, Y.-W, Rettberg, L.A, Jensen, G.J. | Deposit date: | 2015-11-24 | Release date: | 2016-03-16 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY | Cite: | Architecture of the type IVa pilus machine. Science, 351, 2016
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4YTM
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![BU of 4ytm by Molmil](/molmil-images/mine/4ytm) | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with N-biphenyl-3-yl-2-(trifluoromethyl)benzamide | Descriptor: | Cytochrome b-large subunit, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | Authors: | Harada, S, Shiba, T, Sato, D, Yamamoto, A, Nagahama, M, Yone, A, Inaoka, D.K, Sakamoto, K, Inoue, M, Honma, T, Kita, K. | Deposit date: | 2015-03-18 | Release date: | 2015-08-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria Int J Mol Sci, 16, 2015
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8YA4
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8YBH
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8Y9W
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4YWO
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![BU of 4ywo by Molmil](/molmil-images/mine/4ywo) | Mercuric reductase from Metallosphaera sedula | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Mercuric reductase | Authors: | Artz, J.H, Zadvornyy, O.A, White, S, Peters, J.W. | Deposit date: | 2015-03-20 | Release date: | 2015-09-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Biochemical and Structural Properties of a Thermostable Mercuric Ion Reductase from Metallosphaera sedula. Front Bioeng Biotechnol, 3, 2015
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8XBU
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![BU of 8xbu by Molmil](/molmil-images/mine/8xbu) | The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome with the linker DNA binding | Descriptor: | DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ... | Authors: | Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | Deposit date: | 2023-12-07 | Release date: | 2024-03-27 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.24 Å) | Cite: | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
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4YWV
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![BU of 4ywv by Molmil](/molmil-images/mine/4ywv) | Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes | Descriptor: | 4-oxobutanoic acid, SULFATE ION, Succinic semialdehyde dehydrogenase | Authors: | Park, S.A, Jang, E.H, Chi, Y.M, Lee, K.S. | Deposit date: | 2015-03-21 | Release date: | 2015-05-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insight into the substrate inhibition mechanism of NADP(+)-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes. Biochem.Biophys.Res.Commun., 461, 2015
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8XBY
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![BU of 8xby by Molmil](/molmil-images/mine/8xby) | The cryo-EM structure of the RAD51 L1 and L2 loops bound to the linker DNA with the blunt end of the nucleosome | Descriptor: | DNA (5'-D(P*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*CP*CP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*CP*GP*TP*T)-3'), DNA repair protein RAD51 homolog 1 | Authors: | Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | Deposit date: | 2023-12-07 | Release date: | 2024-03-27 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
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8XBW
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![BU of 8xbw by Molmil](/molmil-images/mine/8xbw) | The cryo-EM structure of the RAD51 N-terminal lobe domain bound to the histone H4 tail of the nucleosome | Descriptor: | DNA (5'-D(P*AP*CP*CP*GP*CP*TP*TP*AP*AP*AP*CP*GP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*CP*GP*TP*TP*TP*AP*AP*GP*CP*GP*GP*T)-3'), DNA repair protein RAD51 homolog 1, ... | Authors: | Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | Deposit date: | 2023-12-07 | Release date: | 2024-03-27 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
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8PH7
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![BU of 8ph7 by Molmil](/molmil-images/mine/8ph7) | X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(DPhF)(O2CCH3)3] in condition A | Descriptor: | Lysozyme C, SODIUM ION, SUCCINIC ACID, ... | Authors: | Teran, A, Ferraro, G, Merlino, A. | Deposit date: | 2023-06-19 | Release date: | 2023-09-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.406 Å) | Cite: | Steric hindrance and charge influence on the cytotoxic activity and protein binding properties of diruthenium complexes. Int.J.Biol.Macromol., 253, 2023
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4YHA
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