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7U4S
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BU of 7u4s by Molmil
Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from Candida albicans
Descriptor: GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase
Authors:Miranda, R.R, Silva, M, Iulek, J.
Deposit date:2022-02-28
Release date:2022-04-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Expression, purification, crystallization and structure of Glyceraldehyde-3-Phosphate Dehydrogenase from Candida albicans, main causative agent of candidiasis
Chem. Data Coll., 39, 2022
7TVF
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BU of 7tvf by Molmil
Crystal structure of the SHOC2-MRAS-PP1CA (SMP) complex to a resolution of 2.17 Angstrom
Descriptor: CHLORIDE ION, GLYCEROL, Leucine-rich repeat protein SHOC-2, ...
Authors:Bonsor, D.A, Simanshu, D.K.
Deposit date:2022-02-04
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome.
Nat.Struct.Mol.Biol., 29, 2022
7TVG
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BU of 7tvg by Molmil
Crystal Structure of SHOC2 to a resolution of 2.4 Angstrom
Descriptor: CHLORIDE ION, Leucine-rich repeat protein SHOC-2, SULFATE ION
Authors:Bonsor, D.A, Simanshu, D.K.
Deposit date:2022-02-04
Release date:2022-05-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome.
Nat.Struct.Mol.Biol., 29, 2022
8U87
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BU of 8u87 by Molmil
Structural Basis of Human NOX5 Activation
Descriptor: DODECANE, FLAVIN-ADENINE DINUCLEOTIDE, HEME B/C, ...
Authors:Cui, C, Jiang, M, Sun, J.
Deposit date:2023-09-16
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Structural Basis of Human NOX5 Activation
To Be Published
8U85
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BU of 8u85 by Molmil
Structural Basis of Human NOX5 Activation
Descriptor: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Cui, C, Jiang, M, Sun, J.
Deposit date:2023-09-15
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural Basis of Human NOX5 Activation
To Be Published
8UMV
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BU of 8umv by Molmil
Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex with narrow PCNA opening state I (state 5)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, DNA (20-MER), ...
Authors:Wang, F, He, Q, Li, H.
Deposit date:2023-10-18
Release date:2024-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
7TT8
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BU of 7tt8 by Molmil
Human LRH-1 LBD bound to agonist 6N-10CA and fragment of Tif2 coactivator
Descriptor: 10-[(3aR,6S,6aR)-3-phenyl-3a-(1-phenylethenyl)-6-(sulfamoylamino)-1,3a,4,5,6,6a-hexahydropentalen-2-yl]decanoic acid (non-preferred name), Nuclear receptor coactivator 2, Nuclear receptor subfamily 5 group A member 2
Authors:Cato, M.L, Ortlund, E.A.
Deposit date:2022-01-31
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding Pocket.
J.Med.Chem., 65, 2022
8UMT
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BU of 8umt by Molmil
Atomic model of the human CTF18-RFC-PCNA binary complex in the three-subunit binding state (state 2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, MAGNESIUM ION, ...
Authors:Wang, F, He, Q, Li, H.
Deposit date:2023-10-18
Release date:2024-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
8VF3
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BU of 8vf3 by Molmil
The crystal structure of GALQE CYP199A4 bound to 4-methoxybenzoic acid
Descriptor: 4-METHOXYBENZOIC ACID, ACETATE ION, CHLORIDE ION, ...
Authors:Podgorski, M.N, Bell, S.G.
Deposit date:2023-12-21
Release date:2024-05-08
Method:X-RAY DIFFRACTION (1.469 Å)
Cite:Engineering Peroxygenase Activity into Cytochrome P450 Monooxygenases through Modification of the Oxygen Binding Region
Acs Catalysis, 2024
7OH2
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BU of 7oh2 by Molmil
Crystal structure of FMNH2-dependent monooxygenase for oxidative desulfurization of sulfoquinovose
Descriptor: Alkanesulfonate monooxygenase
Authors:Sharma, M, Davies, G.J.
Deposit date:2021-05-08
Release date:2022-01-19
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria.
Proc.Natl.Acad.Sci.USA, 119, 2022
8UJM
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BU of 8ujm by Molmil
Crystal structure of human CTDNEP1-NEP1R1 protein phosphatase complex with magnesium
Descriptor: CTD nuclear envelope phosphatase 1,Nuclear envelope phosphatase-regulatory subunit 1, MAGNESIUM ION
Authors:Gao, S, Airola, M.V.
Deposit date:2023-10-11
Release date:2024-05-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.161 Å)
Cite:Structure and mechanism of the human CTDNEP1-NEP1R1 membrane protein phosphatase complex necessary to maintain ER membrane morphology.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UJL
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BU of 8ujl by Molmil
Crystal structure of human CTDNEP1-NEP1R1 protein phosphatase complex
Descriptor: CTD nuclear envelope phosphatase 1,Nuclear envelope phosphatase-regulatory subunit 1
Authors:Gao, S, Airola, M.V.
Deposit date:2023-10-11
Release date:2024-05-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure and mechanism of the human CTDNEP1-NEP1R1 membrane protein phosphatase complex necessary to maintain ER membrane morphology.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UN0
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BU of 8un0 by Molmil
Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex with cracked and closed PCNA (state 7)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, DNA (20-MER), ...
Authors:Wang, F, He, Q, Li, H.
Deposit date:2023-10-18
Release date:2024-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UMY
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BU of 8umy by Molmil
Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex with narrow PCNA opening state II (state 6)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, DNA (20-MER), ...
Authors:Wang, F, He, Q, Li, H.
Deposit date:2023-10-18
Release date:2024-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
8VFR
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BU of 8vfr by Molmil
The crystal structure of 4-methylbenzoic acid-bound GALQE CYP199A4 after soaking in 10 mM H2O2 for 5 minutes
Descriptor: 4-(hydroxymethyl)benzoic acid, 4-METHYLBENZOIC ACID, CHLORIDE ION, ...
Authors:Podgorski, M.N, Bell, S.G.
Deposit date:2023-12-21
Release date:2024-05-08
Method:X-RAY DIFFRACTION (2.018 Å)
Cite:Engineering Peroxygenase Activity into Cytochrome P450 Monooxygenases through Modification of the Oxygen Binding Region
Acs Catalysis, 2024
7OFX
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BU of 7ofx by Molmil
Crystal structure of a GH31 family sulfoquinovosidase mutant D455N from Agrobacterium tumefaciens in complex with sulfoquinovosyl glycerol (SQGro)
Descriptor: Alpha-glucosidase yihQ, [(2S,3S,4S,5R,6S)-6-[(2R)-2,3-bis(oxidanyl)propoxy]-3,4,5-tris(oxidanyl)oxan-2-yl]methanesulfonic acid
Authors:Sharma, M, Davies, G.J.
Deposit date:2021-05-05
Release date:2022-01-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria.
Proc.Natl.Acad.Sci.USA, 119, 2022
8VF0
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BU of 8vf0 by Molmil
The crystal structure of QE CYP199A4 bound to 4-methoxybenzoic acid
Descriptor: 4-METHOXYBENZOIC ACID, CHLORIDE ION, Cytochrome P450 enzyme (CYP199A4), ...
Authors:Podgorski, M.N, Bell, S.G.
Deposit date:2023-12-21
Release date:2024-05-08
Method:X-RAY DIFFRACTION (2.028 Å)
Cite:Engineering Peroxygenase Activity into Cytochrome P450 Monooxygenases through Modification of the Oxygen Binding Region
Acs Catalysis, 2024
8U47
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BU of 8u47 by Molmil
Crystal structure of Bacteroides thetaiotaomicron VPI-5482 Endoglycosidase BT1285
Descriptor: Endo-beta-N-acetylglucosaminidase, MAGNESIUM ION, PHOSPHATE ION
Authors:Sastre, D.E, Sultana, N, Sundberg, E.J.
Deposit date:2023-09-09
Release date:2024-05-29
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate.
Nat Commun, 15, 2024
7TOD
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BU of 7tod by Molmil
Solution structure of the phosphatidylinositol 3-phosphate binding domain from the Legionella effector SetA
Descriptor: Subversion of eukaryotic traffic protein A
Authors:Beck, W.H.J, Enoki, T.A, Feigenson, G.W, Nicholson, L, Oswald, R, Mao, Y.
Deposit date:2022-01-24
Release date:2023-02-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of the phosphatidylinositol 3-phosphate binding domain from the Legionella effector SetA
To Be Published
7TSW
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BU of 7tsw by Molmil
Crystal Structure Of Human NADH-Cytochrome B5 Reductase T117D Mutant
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3
Authors:Zheng, A, Thibodeau, P.H.
Deposit date:2022-01-31
Release date:2023-02-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure Of wild-type Human NADH-Cytochrome B5 Reductase and mutants
To be published
8VZ7
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BU of 8vz7 by Molmil
Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan
Descriptor: Cytochrome P450 2C9, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Shah, M.B.
Deposit date:2024-02-11
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan.
J.Inorg.Biochem., 258, 2024
7TTK
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BU of 7ttk by Molmil
Stable-5-LOX
Descriptor: Arachidonate 5-lipoxygenase, FE (II) ION
Authors:Gilbert, N.C, Newcomer, M.E.
Deposit date:2022-02-01
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Stable-5-LOX "closed"
To Be Published
7OY2
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BU of 7oy2 by Molmil
High resolution structure of cytochrome bd-II oxidase from E. coli
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(2~{E},6~{E},10~{Z},14~{E},18~{E},22~{E},26~{E})-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaenyl]naphthalene-1,4-dione, CARDIOLIPIN, ...
Authors:Grund, T.N, Wu, D, Bald, D, Michel, H, Safarian, S.
Deposit date:2021-06-23
Release date:2021-12-15
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.06 Å)
Cite:Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli .
Proc.Natl.Acad.Sci.USA, 118, 2021
7P0R
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BU of 7p0r by Molmil
Crystal structure of L-Trp/Indoleamine 2,3-dioxygenase (hIDO1) complex with the JK-loop refined in the intermediate conformation
Descriptor: GLYCEROL, Indoleamine 2,3-dioxygenase 1, N'-Formylkynurenine, ...
Authors:Mirgaux, M, Wouters, J.
Deposit date:2021-06-30
Release date:2021-12-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site.
Int J Tryptophan Res, 14, 2021
7U4W
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BU of 7u4w by Molmil
The ubiquitin-associated domain of human thirty-eight negative kinase-1 flexibly fused to the 1TEL crystallization chaperone via a 2-glycine linker and crystallized at traditional protein concentration
Descriptor: Transcription factor ETV6,Non-receptor tyrosine-protein kinase TNK1
Authors:Nawarathnage, S, Pedroza Romo, M.J, Smith, T, Bunn, D, Stewart, C, Doukov, T, Moody, J.D.
Deposit date:2022-03-01
Release date:2023-03-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1 UBA domain.
Structure, 31, 2023

223790

건을2024-08-14부터공개중

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