6WX6
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2AJA
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![BU of 2aja by Molmil](/molmil-images/mine/2aja) | X-Ray structure of an ankyrin repeat family protein Q5ZSV0 from Legionella pneumophila. Northeast Structural Genomics Consortium target LgR21. | Descriptor: | ankyrin repeat family protein | Authors: | Kuzin, A.P, Chen, Y, Acton, T, Xiao, R, Conover, K, Ma, C, Kellie, R, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-08-01 | Release date: | 2005-08-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | X-Ray structure of an ankyrin repeat family protein Q5ZSV0 from Legionella pneumophila. To be Published
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6WU9
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2AXK
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![BU of 2axk by Molmil](/molmil-images/mine/2axk) | Solution structure of discrepin, a scorpion venom toxin blocking K+ channels. | Descriptor: | discrepin | Authors: | Prochnicka-Chalufour, A, Corzo, G, Satake, H, Martin-Eauclaire, M.-F, Murgia, A.R, Prestipino, G, D'Suze, G, Possani, L.D, Delepierre, M. | Deposit date: | 2005-09-05 | Release date: | 2006-06-20 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily. Biochemistry, 45, 2006
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2B7M
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2B8K
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![BU of 2b8k by Molmil](/molmil-images/mine/2b8k) | 12-subunit RNA Polymerase II | Descriptor: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... | Authors: | Meyer, P.A, Ye, P, Zhang, M, Suh, M.H, Fu, J. | Deposit date: | 2005-10-07 | Release date: | 2006-06-20 | Last modified: | 2012-06-13 | Method: | X-RAY DIFFRACTION (4.15 Å) | Cite: | Phasing RNA Polymerase II Using Intrinsically Bound Zn Atoms: An Updated Structural Model. Structure, 14, 2006
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2BB3
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![BU of 2bb3 by Molmil](/molmil-images/mine/2bb3) | Crystal Structure of Cobalamin Biosynthesis Precorrin-6Y Methylase (cbiE) from Archaeoglobus fulgidus | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, cobalamin biosynthesis precorrin-6Y methylase (cbiE) | Authors: | Kim, Y, Joachimiak, A, Xu, X, Savchenko, A, Edwards, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-10-17 | Release date: | 2005-11-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal Structure of Cobalamin Biosynthesis Precorrin-6Y Methylase (cbiE) from Archaeoglobus fulgidus To be Published
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6X2K
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2AJ2
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![BU of 2aj2 by Molmil](/molmil-images/mine/2aj2) | X-Ray Crystal Structure of Protein VC0467 from Vibrio cholerae. Northeast Structural Genomics Consortium Target VcR8. | Descriptor: | Hypothetical UPF0301 protein VC0467 | Authors: | Kuzin, A.P, Abashidze, M, Vorobiev, S.M, Acton, T, Xiao, R, Conover, K, Ma, L.-C, Kellie, R, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-08-01 | Release date: | 2005-09-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | X-Ray structure of hypothetical protein VC0467 from Vibrio cholerae: new fold. Northeast Structural Genomics Consortium target VcR8. To be Published
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6WQX
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![BU of 6wqx by Molmil](/molmil-images/mine/6wqx) | Human PRPK-TPRKB complex | Descriptor: | EKC/KEOPS complex subunit TP53RK, EKC/KEOPS complex subunit TPRKB, MAGNESIUM ION, ... | Authors: | Li, J, Ma, X.L, Banerjee, S, Dong, Z.G. | Deposit date: | 2020-04-29 | Release date: | 2021-02-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Crystal structure of the human PRPK-TPRKB complex. Commun Biol, 4, 2021
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6WDP
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![BU of 6wdp by Molmil](/molmil-images/mine/6wdp) | Interleukin 12 receptor subunit beta-1 | Descriptor: | GLYCEROL, Interleukin-12 receptor subunit beta-1, SULFATE ION | Authors: | Spangler, J.B, Thomas, C, Jude, K.M, Garcia, K.C. | Deposit date: | 2020-04-01 | Release date: | 2021-02-24 | Last modified: | 2021-12-01 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells. Cell, 184, 2021
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2AMP
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![BU of 2amp by Molmil](/molmil-images/mine/2amp) | Crystal Structure Of Porcine Transmissible Gastroenteritis Virus Mpro in Complex with an Inhibitor N1 | Descriptor: | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | Authors: | Yang, H, Xue, X, Yang, K, Zhao, Q, Bartlam, M, Rao, Z. | Deposit date: | 2005-08-10 | Release date: | 2005-09-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases. Plos Biol., 3, 2005
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6WLE
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![BU of 6wle by Molmil](/molmil-images/mine/6wle) | Crystal structure of the Zeitlupe light-state mimic G46A | Descriptor: | 1,2-ETHANEDIOL, Adagio protein 1, FLAVIN MONONUCLEOTIDE | Authors: | Zoltowski, B, Green, R. | Deposit date: | 2020-04-20 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Steric and Electronic Interactions at Gln154 in ZEITLUPE Induce Reorganization of the LOV Domain Dimer Interface. Biochemistry, 60, 2021
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6WLP
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![BU of 6wlp by Molmil](/molmil-images/mine/6wlp) | Crystal Structure of the ZTL light-state mimic G46S | Descriptor: | 1,2-ETHANEDIOL, Adagio protein 1, FLAVIN MONONUCLEOTIDE | Authors: | Zoltowski, B, Green, R. | Deposit date: | 2020-04-20 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Steric and Electronic Interactions at Gln154 in ZEITLUPE Induce Reorganization of the LOV Domain Dimer Interface. Biochemistry, 60, 2021
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2ANM
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![BU of 2anm by Molmil](/molmil-images/mine/2anm) | Ternary complex of an orally active thrombin inhibitor with human thrombin and a c-terminal hirudin derived exo-sit inhibitor | Descriptor: | 2-((R)-1-((S)-2-(N-(6-CARBAMIMIDOYLPYRIDIN-3-YL)METHYLCARBAMOYL)-2H-PYRROL-1(5H)-YL)-3-CYCLOHEXYL-1-OXOPROPAN-2-YLAMINO)ACETIC ACID, thrombin | Authors: | Lange, U.E.W, Baucke, D, Hornberger, W, Mack, H, Seitz, W, Hoeffken, H.W. | Deposit date: | 2005-08-11 | Release date: | 2006-06-13 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Orally active thrombin inhibitors. Part 2: optimization of the P2-moiety Bioorg.Med.Chem.Lett., 16, 2006
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6WKA
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![BU of 6wka by Molmil](/molmil-images/mine/6wka) | human carbonic anhydrase II bound to an inhibitor modified with azidothymidine | Descriptor: | 3'-deoxy-3'-(4-{[(4-sulfamoylphenyl)amino]methyl}-1H-1,2,3-triazol-1-yl)thymidine, Carbonic anhydrase 2, ZINC ION | Authors: | Peat, T.S. | Deposit date: | 2020-04-15 | Release date: | 2021-02-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Azidothymidine "Clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors. J.Med.Chem., 63, 2020
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6WTG
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![BU of 6wtg by Molmil](/molmil-images/mine/6wtg) | SdeA DUB Domain in complex with Ubiquitin | Descriptor: | Ubiquitin, Ubiquitinating/deubiquitinating enzyme SdeA | Authors: | Kenny, S, Sheedlo, M, Das, C. | Deposit date: | 2020-05-02 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Insights into Ubiquitin Product Release in Hydrolysis Catalyzed by the Bacterial Deubiquitinase SdeA. Biochemistry, 60, 2021
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7CBC
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6WWA
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![BU of 6wwa by Molmil](/molmil-images/mine/6wwa) | Crystal structure of human SHLD2-SHLD3-REV7 complex | Descriptor: | Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2,Shieldin complex subunit 3 chimera | Authors: | Xie, W, Patel, D.J. | Deposit date: | 2020-05-08 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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6X46
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![BU of 6x46 by Molmil](/molmil-images/mine/6x46) | NMR solution structure of Asterix/Gtsf1 from mouse (CHHC zinc finger domains) | Descriptor: | Gametocyte-specific factor 1, ZINC ION | Authors: | Ipsaro, J.J, O'Brien, P.A, Bhattacharya, S, Palmer III, A.G, Joshua-Tor, L. | Deposit date: | 2020-05-22 | Release date: | 2021-03-03 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons. Cell Rep, 34, 2021
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6WW9
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![BU of 6ww9 by Molmil](/molmil-images/mine/6ww9) | Crystal structure of human REV7(R124A)-SHLD3(35-58) complex | Descriptor: | Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 3 | Authors: | Xie, W, Patel, D.J. | Deposit date: | 2020-05-08 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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2AXU
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![BU of 2axu by Molmil](/molmil-images/mine/2axu) | Structure of PrgX | Descriptor: | PrgX | Authors: | Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.K, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A. | Deposit date: | 2005-09-06 | Release date: | 2005-12-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis. Proc.Natl.Acad.Sci.Usa, 102, 2005
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6WO6
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6WY8
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![BU of 6wy8 by Molmil](/molmil-images/mine/6wy8) | Tcur3481-Tcur3483 steroid ACAD | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acyl-CoA dehydrogenase domain protein Tcur3481, Acyl-CoA dehydrogenase domain protein Tcur3483, ... | Authors: | Kimber, M.S, Stirling, A.J, Seah, S.Y.K. | Deposit date: | 2020-05-12 | Release date: | 2021-03-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Key Glycine in Bacterial Steroid-Degrading Acyl-CoA Dehydrogenases Allows Flavin-Ring Repositioning and Modulates Substrate Side Chain Specificity. Biochemistry, 59, 2020
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6WVW
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![BU of 6wvw by Molmil](/molmil-images/mine/6wvw) | Crystal structure of the R59P-SNAP25 containing SNARE complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Synaptosomal-associated protein 25, ... | Authors: | Zhou, Q, White, K.I, Brunger, A.T. | Deposit date: | 2020-05-07 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies. Neuron, 109, 2021
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