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7SG2
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BU of 7sg2 by Molmil
XPA5 TCR in complex with HLA-DQ2-omega1
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Ciacchi, L, Farenc, C, Petersen, J, Reid, H.H, Rossjohn, J.
Deposit date:2021-10-04
Release date:2022-02-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease.
J.Biol.Chem., 298, 2022
2VLR
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BU of 2vlr by Molmil
The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain
Descriptor: BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Ishizuka, J, Stewart-Jones, G, van der Merwe, A, Bell, J, McMichael, A, Jones, Y.
Deposit date:2008-01-15
Release date:2008-01-22
Last modified:2019-09-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28, 2008
2VLJ
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BU of 2vlj by Molmil
The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain
Descriptor: BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Ishizuka, J, Stewart-Jones, G, Van Der Merwe, A, Bell, J, Mcmichael, A, Jones, Y.
Deposit date:2008-01-15
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28, 2008
2VIS
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BU of 2vis by Molmil
INFLUENZA VIRUS HEMAGGLUTININ, (ESCAPE) MUTANT WITH THR 131 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, ...
Authors:Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
Deposit date:1997-12-22
Release date:1998-04-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
2VLL
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BU of 2vll by Molmil
The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain
Descriptor: BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Ishizuka, J, Stewart-Jones, G, Van Der Merwe, A, Bell, J, Mcmichael, A, Jones, Y.
Deposit date:2008-01-15
Release date:2008-01-22
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain
Immunity, 28, 2008
2VAB
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BU of 2vab by Molmil
MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND SENDAI VIRUS NUCLEOPROTEIN
Descriptor: BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, SENDAI VIRUS NUCLEOPROTEIN
Authors:Fremont, D.H, Wilson, I.A.
Deposit date:1994-11-01
Release date:1996-06-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb.
Science, 257, 1992
2XPG
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BU of 2xpg by Molmil
Crystal structure of a MHC class I-peptide complex
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-3 ALPHA CHAIN, ...
Authors:McMahon, R.M, Friis, L, Siebold, C, Friese, M.A, Fugger, L, Jones, E.Y.
Deposit date:2010-08-26
Release date:2011-04-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of Hla-A0301 in Complex with a Peptide of Proteolipid Protein: Insights Into the Role of Hla-A Alleles in Susceptibility to Multiple Sclerosis
Acta Crystallogr.,Sect.D, 67, 2011
2HT4
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BU of 2ht4 by Molmil
Structure of the Escherichia coli ClC chloride channel Y445W mutant and Fab complex
Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-25
Release date:2006-09-19
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger.
J.Mol.Biol., 362, 2006
2HN7
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BU of 2hn7 by Molmil
HLA-A*1101 in complex with HBV peptide homologue
Descriptor: Beta-2-microglobulin, DNA polymerase PEPTIDE HOMOLOGUE, HLA class I histocompatibility antigen, ...
Authors:Blicher, T.
Deposit date:2006-07-12
Release date:2006-11-28
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue.
Acta Crystallogr.,Sect.F, 62, 2006
2HLA
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BU of 2hla by Molmil
SPECIFICITY POCKETS FOR THE SIDE CHAINS OF PEPTIDE ANTIGENS IN HLA-AW68
Descriptor: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-Aw68)
Authors:Garrett, T.P.J, Saper, M.A, Wiley, D.C.
Deposit date:1989-10-05
Release date:1990-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Specificity pockets for the side chains of peptide antigens in HLA-Aw68.
Nature, 342, 1989
8VZ8
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BU of 8vz8 by Molmil
Crystal structure of mouse MAIT M2B TCR-MR1-5-OP-RU complex
Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
Authors:Ciacchi, L, Rossjohn, J, Awad, W.
Deposit date:2024-02-11
Release date:2024-04-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Mouse mucosal-associated invariant T cell receptor recognition of MR1 presenting the vitamin B metabolite, 5-(2-oxopropylideneamino)-6-d-ribitylaminouracil.
J.Biol.Chem., 300, 2024
8VZ9
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BU of 8vz9 by Molmil
Crystal structure of mouse MAIT M2A TCR-MR1-5-OP-RU complex
Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
Authors:Ciacchi, L, Rossjohn, J, Awad, W.
Deposit date:2024-02-11
Release date:2024-04-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Mouse mucosal-associated invariant T cell receptor recognition of MR1 presenting the vitamin B metabolite, 5-(2-oxopropylideneamino)-6-d-ribitylaminouracil.
J.Biol.Chem., 300, 2024
2I5Y
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BU of 2i5y by Molmil
Crystal structure of CD4M47, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 GP120 envelope glycoprotein and anti-HIV-1 antibody 17B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 17B Heavy chain, Antibody 17B Light chain, ...
Authors:Huang, C.-C, Kwong, P.D.
Deposit date:2006-08-26
Release date:2006-10-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein.
J.Mol.Biol., 382, 2008
2IAD
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BU of 2iad by Molmil
CLASS II MHC I-AD IN COMPLEX WITH AN INFLUENZA HEMAGGLUTININ PEPTIDE 126-138
Descriptor: MHC CLASS II I-AD
Authors:Scott, C.A, Peterson, P.A, Teyton, L, Wilson, I.A.
Deposit date:1998-03-13
Release date:1998-11-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues.
Immunity, 8, 1998
2X4S
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BU of 2x4s by Molmil
Crystal structure of MHC CLass I HLA-A2.1 bound to a peptide representing the epitope of the H5N1 (Avian Flu) Nucleoprotein
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ...
Authors:Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M.
Deposit date:2010-02-02
Release date:2010-03-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Uv-Induced Ligand Exchange in Mhc Class I Protein Crystals
J.Am.Chem.Soc., 131, 2009
2JIX
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BU of 2jix by Molmil
Crystal structure of ABT-007 FAB fragment with the soluble domain of EPO receptor
Descriptor: ABT-007 FAB FRAGMENT, ERYTHROPOIETIN RECEPTOR
Authors:Liu, Z, Stoll, V.S, DeVries, P, Jakob, C.G, Xie, N, Simmer, R.L, Lacy, S.E, Egan, D.A, Harlan, J.E, Lesniewski, R.R, Reilly, E.B.
Deposit date:2007-07-02
Release date:2007-07-10
Last modified:2020-03-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A Potent Erythropoietin-Mimicking Human Antibody Interacts Through a Novel Binding Site.
Blood, 110, 2007
2XN9
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BU of 2xn9 by Molmil
Crystal structure of the ternary complex between human T cell receptor, staphylococcal enterotoxin H and human major histocompatibility complex class II
Descriptor: ENTEROTOXIN H, GLYCEROL, HEMAGGLUTININ, ...
Authors:Saline, M, Rodstrom, K.E.J, Fischer, G, Orekhov, V.Y, Karlsson, B.G, Lindkvist-Petersson, K.
Deposit date:2010-07-31
Release date:2010-11-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structure of Superantigen Complexed with Tcr and Mhc Reveals Novel Insights Into Superantigenic T Cell Activation.
Nat.Commun., 1, 2010
2YPK
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BU of 2ypk by Molmil
Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN, ...
Authors:Stewart-Jones, G.B, Simpson, P, Van Der Merwe, P.A, Easterbrook, P, Mcmichael, A.J, Rowland-Jones, S.L, Jones, E.Y, Gillespie, G.M.
Deposit date:2012-10-30
Release date:2012-11-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms.
Proc.Natl.Acad.Sci.USA, 109, 2012
2MHA
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BU of 2mha by Molmil
CRYSTAL STRUCTURE OF THE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I H-2KB MOLECULE CONTAINING A SINGLE VIRAL PEPTIDE: IMPLICATIONS FOR PEPTIDE BINDING AND T-CELL RECEPTOR RECOGNITION
Descriptor: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (H-2KB) (ALPHA CHAIN), VIRAL OCTAPEPTIDE ARG-GLY-TYR-VAL-TYR-GLN-GLY-LEU
Authors:Zhang, W, Young, A.C.M, Imarai, M, Nathenson, S.G, Sacchettini, J.C.
Deposit date:1993-07-21
Release date:1993-10-31
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition.
Proc.Natl.Acad.Sci.USA, 89, 1992
5IB4
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BU of 5ib4 by Molmil
Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR and Nickel
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B.
Deposit date:2016-02-22
Release date:2017-02-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
J.Biol.Chem., 2019
8ESB
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BU of 8esb by Molmil
CryoEM structure of HLA-A2 bound to MAGEA8 (232-241) peptide
Descriptor: Beta-2-microglobulin,HLA class I antigen,MAGE-A8 peptide chimera
Authors:Saotome, K, Franklin, M.C.
Deposit date:2022-10-13
Release date:2023-05-03
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.
Nat Commun, 14, 2023
8ES9
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BU of 8es9 by Molmil
CryoEM structure of PN45428 TCR-CD3 in complex with HLA-A2 MAGEA4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
Authors:Saotome, K, Franklin, M.C.
Deposit date:2022-10-13
Release date:2023-05-03
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.
Nat Commun, 14, 2023
8ESA
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BU of 8esa by Molmil
CryoEM structure of HLA-A2 bound to MAGEA4 (230-239) peptide
Descriptor: Beta-2-microglobulin,HLA class I antigen,MAGE-A4 peptide chimera
Authors:Saotome, K, Franklin, M.C.
Deposit date:2022-10-13
Release date:2023-05-03
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.
Nat Commun, 14, 2023
4X5X
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BU of 4x5x by Molmil
HLA-DR1 mutant bN82A with covalently linked CLIP106-120(M107W)
Descriptor: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain
Authors:Guenther, S, Freund, C.
Deposit date:2014-12-06
Release date:2016-03-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.199 Å)
Cite:MHC class II complexes sample intermediate states along the peptide exchange pathway.
Nat Commun, 7, 2016
8ES8
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BU of 8es8 by Molmil
CryoEM structure of PN45545 TCR-CD3 in complex with HLA-A2 MAGEA4 (230-239)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
Authors:Saotome, K, Franklin, M.C.
Deposit date:2022-10-13
Release date:2023-05-03
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.
Nat Commun, 14, 2023

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