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5V9X
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BU of 5v9x by Molmil
Structure of Mycobacterium smegmatis helicase Lhr bound to ssDNA and AMP-PNP
Descriptor: ATP-dependent DNA helicase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Ordonez, H, Jacewicz, A, Ferrao, R, Shuman, S.
Deposit date:2017-03-23
Release date:2017-12-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.797 Å)
Cite:Structure of mycobacterial 3'-to-5' RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases.
Nucleic Acids Res., 46, 2018
5VWO
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BU of 5vwo by Molmil
Ornithine aminotransferase inactivated by (1R,3S,4S)-3-amino-4-fluorocyclopentane-1-carboxylic acid (FCP)
Descriptor: (1S,3S,4E)-3-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-4-iminocyclopentane-1-carboxylic acid, Ornithine aminotransferase, mitochondrial
Authors:Mascarenhas, R, Liu, D, Le, H, Silverman, R.
Deposit date:2017-05-22
Release date:2017-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.773 Å)
Cite:Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5'-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover.
Biochemistry, 56, 2017
4FQG
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BU of 4fqg by Molmil
Crystal structure of the TCERG1 FF4-6 tandem repeat domain
Descriptor: CHLORIDE ION, NICKEL (II) ION, Transcription elongation regulator 1
Authors:Liu, J, Fan, S, Lee, C.J, Greenleaf, A.L, Zhou, P.
Deposit date:2012-06-25
Release date:2013-02-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7 within the Carboxyl-terminal Domain Repeat.
J.Biol.Chem., 288, 2013
7Z11
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BU of 7z11 by Molmil
Structure of substrate bound DRG1 (AFG2)
Descriptor: ATPase family gene 2 protein, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, peptide substrate
Authors:Prattes, M, Grishkovskaya, I, Bergler, H, Haselbach, D.
Deposit date:2022-02-24
Release date:2022-09-21
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1.
Nat.Struct.Mol.Biol., 29, 2022
3HCU
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BU of 3hcu by Molmil
Crystal structure of TRAF6 in complex with Ubc13 in the C2 space group
Descriptor: TNF receptor-associated factor 6, Ubiquitin-conjugating enzyme E2 N, ZINC ION
Authors:Yin, Q, Lin, S.-C, Lamothe, B, Lu, M, Lo, Y.-C, Hura, G, Zheng, L, Rich, R.L, Campos, A.D, Myszka, D.G, Lenardo, M.J, Darnay, B.G, Wu, H.
Deposit date:2009-05-06
Release date:2009-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:E2 interaction and dimerization in the crystal structure of TRAF6.
Nat.Struct.Mol.Biol., 16, 2009
3HCT
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BU of 3hct by Molmil
Crystal structure of TRAF6 in complex with Ubc13 in the P1 space group
Descriptor: TNF receptor-associated factor 6, Ubiquitin-conjugating enzyme E2 N, ZINC ION
Authors:Yin, Q, Lin, S.-C, Lamothe, B, Lu, M, Lo, Y.-C, Hura, G, Zheng, L, Rich, R.L, Campos, A.D, Myszka, D.G, Lenardo, M.J, Darnay, B.G, Wu, H.
Deposit date:2009-05-06
Release date:2009-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:E2 interaction and dimerization in the crystal structure of TRAF6.
Nat.Struct.Mol.Biol., 16, 2009
4G0Y
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BU of 4g0y by Molmil
Crystal structure of Arabidopsis AGO1 in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Protein argonaute 1
Authors:Frank, F, Hauver, J, Sonenberg, N, Nagar, B.
Deposit date:2012-07-10
Release date:2012-07-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs.
Embo J., 31, 2012
4G0Z
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BU of 4g0z by Molmil
Crystal structure of Arabidopsis thaliana AGO1 MID domain in complex with GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, Protein argonaute 1
Authors:Frank, F, Hauver, J, Sonenberg, N, Nagar, B.
Deposit date:2012-07-10
Release date:2012-07-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs.
Embo J., 31, 2012
2N78
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BU of 2n78 by Molmil
NMR structure of IF1 from Pseudomonas aeruginosa
Descriptor: Translation initiation factor IF-1
Authors:Zhang, Y.
Deposit date:2015-09-04
Release date:2016-09-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:(1)H, (13)C and (15)N resonance assignments and secondary structure analysis of translation initiation factor 1 from Pseudomonas aeruginosa.
Biomol.Nmr Assign., 10, 2016
2IUW
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BU of 2iuw by Molmil
Crystal structure of human ABH3 in complex with iron ion and 2- oxoglutarate
Descriptor: 2-OXOGLUTARIC ACID, ALKYLATED REPAIR PROTEIN ALKB HOMOLOG 3, BETA-MERCAPTOETHANOL, ...
Authors:Sundheim, O, Vagbo, C.B, Bjoras, M, deSousa, M.M.L, Talstad, V, Aas, P.A, Drablos, F, Krokan, H.E, Tainer, J.A, Slupphaug, G.
Deposit date:2006-06-07
Release date:2006-07-26
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Human Abh3 Structure and Key Residues for Oxidative Demethylation to Reverse DNA/RNA Damage.
Embo J., 25, 2006
3A26
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BU of 3a26 by Molmil
Crystal structure of P. horikoshii TYW2 in complex with MeSAdo
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, TETRAETHYLENE GLYCOL, Uncharacterized protein PH0793
Authors:Umitsu, M, Nishimasu, H, Ishitani, R, Nureki, O.
Deposit date:2009-04-28
Release date:2009-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2
Proc.Natl.Acad.Sci.USA, 106, 2009
6Y5U
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BU of 6y5u by Molmil
MenT3 (aka TglT), nucleotidyltransferase toxin Rv1045 from Mycobacterium tuberculosis
Descriptor: Rv1045
Authors:Blower, T.R, Usher, B.
Deposit date:2020-02-25
Release date:2020-09-16
Last modified:2021-01-20
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:A nucleotidyltransferase toxin inhibits growth of Mycobacterium tuberculosis through inactivation of tRNA acceptor stems.
Sci Adv, 6, 2020
6Y56
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BU of 6y56 by Molmil
MenT4, nucleotidyltransferase toxin Rv2826c from Mycobacterium tuberculosis H37Rv
Descriptor: Uncharacterized protein
Authors:Usher, B, Blower, T.R.
Deposit date:2020-02-24
Release date:2020-09-16
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:A nucleotidyltransferase toxin inhibits growth of Mycobacterium tuberculosis through inactivation of tRNA acceptor stems.
Sci Adv, 6, 2020
1K5V
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BU of 1k5v by Molmil
Human acidic fibroblast growth factor. 141 amino acid form with amino terminal His tag with Asn106 replaced by Gly (N106G).
Descriptor: Acidic fibroblast growth factor, SULFATE ION
Authors:Kim, J, Blaber, S.I, Blaber, M.
Deposit date:2001-10-12
Release date:2002-02-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Alternative type I and I' turn conformations in the beta8/beta9 beta-hairpin of human acidic fibroblast growth factor.
Protein Sci., 11, 2002
3A25
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BU of 3a25 by Molmil
Crystal structure of P. horikoshii TYW2 in complex with AdoMet
Descriptor: S-ADENOSYLMETHIONINE, Uncharacterized protein PH0793
Authors:Umitsu, M, Nishimasu, H, Ishitani, R, Nureki, O.
Deposit date:2009-04-28
Release date:2009-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2
Proc.Natl.Acad.Sci.USA, 106, 2009
4CRU
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BU of 4cru by Molmil
Complex of human CNOT9 and CNOT1 including one tryptophan
Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, GLYCEROL
Authors:Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O.
Deposit date:2014-03-01
Release date:2014-05-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing
Mol.Cell, 54, 2014
3WY9
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BU of 3wy9 by Molmil
Crystal structure of a complex of the archaeal ribosomal stalk protein aP1 and the GDP-bound archaeal elongation factor aEF1alpha
Descriptor: 50S ribosomal protein L12, Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE
Authors:Ito, K, Honda, T, Suzuki, T, Miyoshi, T, Murakami, R, Yao, M, Uchiumi, T.
Deposit date:2014-08-22
Release date:2014-12-24
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular insights into the interaction of the ribosomal stalk protein with elongation factor 1 alpha.
Nucleic Acids Res., 42, 2014
4NIH
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BU of 4nih by Molmil
Crystal structure of AlkB E136L mutant protein with cofactors bound to dsDNA containing m6A/A
Descriptor: 2-OXOGLUTARIC ACID, 5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3', 5'-D(*TP*AP*GP*GP*TP*AP*AP*(6MA)P*AP*CP*CP*GP*T)-3', ...
Authors:Yi, C.Q, Zhu, C.X.
Deposit date:2013-11-06
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.374 Å)
Cite:Switching Demethylation Activities between AlkB Family RNA/DNA Demethylases through Exchange of Active-Site Residues.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NII
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BU of 4nii by Molmil
Crystal structure of AlkB D135I mutant protein with cofactors bound to dsDNA containing m6A/A
Descriptor: 2-OXOGLUTARIC ACID, 5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3', 5'-D(*TP*AP*GP*GP*TP*AP*AP*(6MA)P*AP*CP*CP*GP*T)-3', ...
Authors:Yi, C.Q, Zhu, C.X.
Deposit date:2013-11-06
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.622 Å)
Cite:Switching Demethylation Activities between AlkB Family RNA/DNA Demethylases through Exchange of Active-Site Residues.
Angew.Chem.Int.Ed.Engl., 53, 2014
3S65
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BU of 3s65 by Molmil
Structures and oxygen affinities of crystalline human hemoglobin C (beta6 Lys) in the R2 quaternary structures
Descriptor: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:Shibayama, N, Sugiyama, K, Park, S.Y.
Deposit date:2011-05-25
Release date:2011-08-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures and oxygen affinities of crystalline human hemoglobin C (beta6 Glu->Lys) in the R and R2 quaternary structure
To be Published
3B4C
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BU of 3b4c by Molmil
T. tengcongensis glmS ribozyme bound to glucosamine-6-phosphate and a substrate RNA with a 2'5'-phosphodiester linkage
Descriptor: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, 3'-DEOXYADENOSINE, MAGNESIUM ION, ...
Authors:Klein, D.J, Ferre-D'Amare, A.R.
Deposit date:2007-10-23
Release date:2007-12-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Essential Role of an Active-Site Guanine in glmS Ribozyme Catalysis.
J.Am.Chem.Soc., 129, 2007
1K5U
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BU of 1k5u by Molmil
Human acidic fibroblast growth factor. 141 amino acid form with amino terminal His tag with His93 replaced by Gly (H93G).
Descriptor: Acidic fibroblast growth factor, SULFATE ION
Authors:Kim, J, Blaber, S.I, Blaber, M.
Deposit date:2001-10-12
Release date:2002-02-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alternative type I and I' turn conformations in the beta8/beta9 beta-hairpin of human acidic fibroblast growth factor.
Protein Sci., 11, 2002
8F19
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BU of 8f19 by Molmil
Cryo-EM structure of Kap114 bound to Gsp1 (RanGTP)
Descriptor: GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Importin subunit beta-5, ...
Authors:Jiou, J, Chook, Y.M.
Deposit date:2022-11-04
Release date:2023-07-26
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
3S66
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BU of 3s66 by Molmil
Structures and oxygen affinities of crystalline human hemoglobin C (beta6 Lys) in the R quaternary structures
Descriptor: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:Shibayama, N, Sugiyama, K, Park, S.Y.
Deposit date:2011-05-25
Release date:2011-08-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Structures and oxygen affinities of crystalline human hemoglobin C (beta6 Glu->Lys) in the R and R2 quaternary structure
To be Published
4CRV
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BU of 4crv by Molmil
Complex of human CNOT9 and CNOT1 including two tryptophans
Descriptor: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, GLYCEROL, ...
Authors:Boland, A, Chen, Y, Izaurralde, E, Weichenrieder, O.
Deposit date:2014-03-01
Release date:2014-05-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing
Mol.Cell, 54, 2014

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